2026 ICD-10-CM Diagnosis Code E16Other disorders of pancreatic internal secretion

ICD-10-CM Codes›E00–E89›E15-E16›E16

ICD-10-CM E16
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

E16 is a non-billable ICD-10-CM category code for other disorders of pancreatic internal secretion, so it cannot be submitted on claims. Use a more specific code from this category instead, such as E16.0, E16.1, E16.2, and E16.3.

Code Identity

ICD-10-CM Code
E16
Billable Status
No — Non-Billable Category
Code Describes
Other disorders of pancreatic internal secretion
Chapter
E15-E16
Other disorders of glucose regulation and pancreatic internal secretion

Code Classification

ChapterE00–E89Endocrine, nutritional and metabolic diseases
SectionE15-E16Other disorders of glucose regulation and pancreatic internal secretion
CategoryE16Other disorders of pancreatic internal secretion
This CodeE16Other disorders of pancreatic internal secretion

Specific Coding for Other disorders of pancreatic internal secretionOverview

Non-specific codes like E16 require more characters. Use one of these billable codes instead:

  • Use E16.0 for Drug-induced hypoglycemia without coma

  • Use E16.1 for Other hypoglycemia

  • Use E16.2 for Hypoglycemia, unspecified

  • Use E16.3 for Increased secretion of glucagon

  • Use E16.4 for Increased secretion of gastrin

  • Use E16.8 for Other specified disorders of pancreatic internal secretion

  • Use E16.9 for Disorder of pancreatic internal secretion, unspecified

  • E16.A for Hypoglycemia level

  • Use E16.A1 for Hypoglycemia level 1

  • Use E16.A2 for Hypoglycemia level 2

  • Use E16.A3 for Hypoglycemia level 3

Patient EducationClinical

Pancreatic Diseases

The pancreas is a gland behind your stomach and in front of your spine. It produces juices that help break down food and hormones that help control blood sugar levels. Problems with the pancreas can lead to many health problems. These include:

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About E16Overview

Is E16 (Other disorders of pancreatic internal secretion) a billable code?

No. This is a category header that groups the codes for other disorders of pancreatic internal secretion, and headers cannot be submitted on claims. Claims for other disorders of pancreatic internal secretion need a more specific code from this category, such as E16.0, E16.1, and E16.2.