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Neoplasms (C00–D49)

Browse all the diagnosis codes used for neoplasms (c00–d49). For easy navigation, the diagnosis codes are sorted in alphabetical order and grouped by sections. Each section is clearly marked with its description, and the corresponding three-digit code range. This format makes it simple to browse diagnosis codes in this chapter or section and find what you're looking for. We've also added green checkmark icons to label billable codes, and red warning icons for non-billable ones. This makes it easy to identify which codes can be billed.

  • Neoplasms (C00–D49)

    Note: Functional activity
    All neoplasms are classified in this chapter, whether they are functionally active or not. An additional code from Chapter 4 may be used, to identify functional activity associated with any neoplasm.

    Morphology [Histology]
    Chapter 2 classifies neoplasms primarily by site (topography), with broad groupings for behavior, malignant, in situ, benign, etc. The Table of Neoplasms should be used to identify the correct topography code. In a few cases, such as for malignant melanoma and certain neuroendocrine tumors, the morphology (histologic type) is included in the category and codes.

    Primary malignant neoplasms overlapping site boundaries
    A primary malignant neoplasm that overlaps two or more contiguous (next to each other) sites should be classified to the subcategory/code .8 ('overlapping lesion'), unless the combination is specifically indexed elsewhere. For multiple neoplasms of the same site that are not contiguous, such as tumors in different quadrants of the same breast, codes for each site should be assigned.

    Malignant neoplasm of ectopic tissue
    Malignant neoplasms of ectopic tissue are to be coded to the site mentioned, e.g., ectopic pancreatic malignant neoplasms are coded to pancreas, unspecified (C25.9).

    • Malignant neoplasms of lip, oral cavity and pharynx (C00-C14)

      • Malignant neoplasm of lip (C00)
      • Malignant neoplasm of base of tongue (C01)
      • Malignant neoplasm of other and unspecified parts of tongue (C02)
      • Malignant neoplasm of gum (C03)
      • Malignant neoplasm of floor of mouth (C04)
      • Malignant neoplasm of palate (C05)
      • Malignant neoplasm of other and unspecified parts of mouth (C06)
      • Malignant neoplasm of parotid gland (C07)
      • Malignant neoplasm of other and unsp major salivary glands (C08)
      • Malignant neoplasm of tonsil (C09)
      • Malignant neoplasm of oropharynx (C10)
      • Malignant neoplasm of nasopharynx (C11)
      • Malignant neoplasm of pyriform sinus (C12)
      • Malignant neoplasm of hypopharynx (C13)
      • Malig neoplasm of sites in the lip, oral cavity and pharynx (C14)

    • Malignant neoplasms of digestive organs (C15-C26)

      • Malignant neoplasm of esophagus (C15)
      • Malignant neoplasm of stomach (C16)
      • Malignant neoplasm of small intestine (C17)
      • Malignant neoplasm of colon (C18)
      • Malignant neoplasm of rectosigmoid junction (C19)
      • Malignant neoplasm of rectum (C20)
      • Malignant neoplasm of anus and anal canal (C21)
      • Malignant neoplasm of liver and intrahepatic bile ducts (C22)
      • Malignant neoplasm of gallbladder (C23)
      • Malignant neoplasm of other and unsp parts of biliary tract (C24)
      • Malignant neoplasm of pancreas (C25)
      • Malignant neoplasm of other and ill-defined digestive organs (C26)

    • Malignant neoplasms of respiratory and intrathoracic organs (C30-C39)

      • Malignant neoplasm of nasal cavity and middle ear (C30)
      • Malignant neoplasm of accessory sinuses (C31)
      • Malignant neoplasm of larynx (C32)
      • Malignant neoplasm of trachea (C33)
      • Malignant neoplasm of bronchus and lung (C34)
      • Malignant neoplasm of thymus (C37)
      • Malignant neoplasm of heart, mediastinum and pleura (C38)
      • Malig neoplm of sites in the resp sys and intrathorac organs (C39)

    • Malignant neoplasms of bone and articular cartilage (C40-C41)

      • Malignant neoplasm of bone and articular cartilage of limbs (C40)
      • Malignant neoplasm of bone/artic cartl of and unsp sites (C41)

    • Melanoma and other malignant neoplasms of skin (C43-C44)

      • Malignant melanoma of skin (C43)
      • Other and unspecified malignant neoplasm of skin (C44)
      • Merkel cell carcinoma (C4A)

    • Malignant neoplasms of mesothelial and soft tissue (C45-C49)

      • Mesothelioma (C45)
      • Kaposi's sarcoma (C46)
      • Malignant neoplasm of prph nerves and autonomic nervous sys (C47)
      • Malignant neoplasm of retroperitoneum and peritoneum (C48)
      • Malignant neoplasm of other connective and soft tissue (C49)

    • Malignant neoplasms of breast (C50)

      • Malignant neoplasm of breast (C50)

    • Malignant neoplasms of female genital organs (C51-C58)

      • Malignant neoplasm of vulva (C51)
      • Malignant neoplasm of vagina (C52)
      • Malignant neoplasm of cervix uteri (C53)
      • Malignant neoplasm of corpus uteri (C54)
      • Malignant neoplasm of uterus, part unspecified (C55)
      • Malignant neoplasm of ovary (C56)
      • Malignant neoplasm of other and unsp female genital organs (C57)
      • Malignant neoplasm of placenta (C58)

    • Malignant neoplasms of male genital organs (C60-C63)

      • Malignant neoplasm of penis (C60)
      • Malignant neoplasm of prostate (C61)
      • Malignant neoplasm of testis (C62)
      • Malignant neoplasm of other and unsp male genital organs (C63)

    • Malignant neoplasms of urinary tract (C64-C68)

      • Malignant neoplasm of kidney, except renal pelvis (C64)
      • Malignant neoplasm of renal pelvis (C65)
      • Malignant neoplasm of ureter (C66)
      • Malignant neoplasm of bladder (C67)
      • Malignant neoplasm of other and unspecified urinary organs (C68)

    • Malignant neoplasms of eye, brain and other parts of central nervous system (C69-C72)

      • Malignant neoplasm of eye and adnexa (C69)
      • Malignant neoplasm of meninges (C70)
      • Malignant neoplasm of brain (C71)
      • Malig neoplm of spinal cord, cranial nerves and oth prt cnsl (C72)

    • Malignant neoplasms of thyroid and other endocrine glands (C73-C75)

      • Malignant neoplasm of thyroid gland (C73)
      • Malignant neoplasm of adrenal gland (C74)
      • Malignant neoplasm of endo glands and related structures (C75)

    • Malignant neuroendocrine tumors (C7A)

      • Malignant neuroendocrine tumors (C7A)

    • Secondary neuroendocrine tumors (C7B)

      • Secondary neuroendocrine tumors (C7B)

    • Malignant neoplasms of ill-defined, other secondary and unspecified sites (C76-C80)

      • Malignant neoplasm of other and ill-defined sites (C76)
      • Secondary and unspecified malignant neoplasm of lymph nodes (C77)
      • Secondary malignant neoplasm of resp and digestive organs (C78)
      • Secondary malignant neoplasm of other and unspecified sites (C79)
      • Malignant neoplasm without specification of site (C80)

    • Malignant neoplasms of lymphoid, hematopoietic and related tissue (C81-C96)

      • Hodgkin lymphoma (C81)
      • Follicular lymphoma (C82)
      • Non-follicular lymphoma (C83)
      • Mature T/NK-cell lymphomas (C84)
      • Oth and unspecified types of non-Hodgkin lymphoma (C85)
      • Other specified types of T/NK-cell lymphoma (C86)
      • Malig immunoproliferative dis and certain oth B-cell lymph (C88)
      • Multiple myeloma and malignant plasma cell neoplasms (C90)
      • Lymphoid leukemia (C91)
      • Myeloid leukemia (C92)
      • Monocytic leukemia (C93)
      • Other leukemias of specified cell type (C94)
      • Leukemia of unspecified cell type (C95)
      • Oth & unsp malig neoplm of lymphoid, hematpoetc and rel tiss (C96)

    • In situ neoplasms (D00-D09)

      • Carcinoma in situ of oral cavity, esophagus and stomach (D00)
      • Carcinoma in situ of other and unspecified digestive organs (D01)
      • Carcinoma in situ of middle ear and respiratory system (D02)
      • Melanoma in situ (D03)
      • Carcinoma in situ of skin (D04)
      • Carcinoma in situ of breast (D05)
      • Carcinoma in situ of cervix uteri (D06)
      • Carcinoma in situ of other and unspecified genital organs (D07)
      • Carcinoma in situ of other and unspecified sites (D09)

    • Benign neoplasms, except benign neuroendocrine tumors (D10-D36)

      • Benign neoplasm of mouth and pharynx (D10)
      • Benign neoplasm of major salivary glands (D11)
      • Benign neoplasm of colon, rectum, anus and anal canal (D12)
      • Benign neoplasm of and ill-defined parts of digestive system (D13)
      • Benign neoplasm of middle ear and respiratory system (D14)
      • Benign neoplasm of other and unsp intrathoracic organs (D15)
      • Benign neoplasm of bone and articular cartilage (D16)
      • Benign lipomatous neoplasm (D17)
      • Hemangioma and lymphangioma, any site (D18)
      • Benign neoplasm of mesothelial tissue (D19)
      • Benign neoplm of soft tissue of retroperiton and peritoneum (D20)
      • Other benign neoplasms of connective and other soft tissue (D21)
      • Melanocytic nevi (D22)
      • Other benign neoplasms of skin (D23)
      • Benign neoplasm of breast (D24)
      • Leiomyoma of uterus (D25)
      • Other benign neoplasms of uterus (D26)
      • Benign neoplasm of ovary (D27)
      • Benign neoplasm of other and unsp female genital organs (D28)
      • Benign neoplasm of male genital organs (D29)
      • Benign neoplasm of urinary organs (D30)
      • Benign neoplasm of eye and adnexa (D31)
      • Benign neoplasm of meninges (D32)
      • Benign neoplasm of brain and oth prt central nervous system (D33)
      • Benign neoplasm of thyroid gland (D34)
      • Benign neoplasm of other and unspecified endocrine glands (D35)
      • Benign neoplasm of other and unspecified sites (D36)

    • Benign neuroendocrine tumors (D3A)

      • Benign neuroendocrine tumors (D3A)

    • Neoplasms of uncertain behavior, polycythemia vera and myelodysplastic syndromes (D37-D48)

      • Neoplasm of uncrt behavior of oral cavity and dgstv organs (D37)
      • Neoplm of uncrt behav of mid ear & resp and intrathorac org (D38)
      • Neoplasm of uncertain behavior of female genital organs (D39)
      • Neoplasm of uncertain behavior of male genital organs (D40)
      • Neoplasm of uncertain behavior of urinary organs (D41)
      • Neoplasm of uncertain behavior of meninges (D42)
      • Neoplasm of uncertain behavior of brain and cnsl (D43)
      • Neoplasm of uncertain behavior of endocrine glands (D44)
      • Polycythemia vera (D45)
      • Myelodysplastic syndromes (D46)
      • Oth neoplm of uncrt behav of lymphoid, hematpoetc & rel tiss (D47)
      • Neoplasm of uncertain behavior of other and unsp sites (D48)

    • Neoplasms of unspecified behavior (D49)

      • Neoplasms of unspecified behavior (D49)