Other disorders of glucose regulation and pancreatic internal secretion (E15-E16)

ICD-10 codes E15 through E16 cover uncommon but important disorders related to abnormal glucose levels and pancreatic hormone secretion that are not caused by diabetes. These include various types of hypoglycemia (low blood sugar) and other problems involving the pancreas’ hormone production, such as excess glucagon or gastrin.

This range specifically codes for conditions like E15 Nondiabetic hypoglycemic coma, also known as insulin coma or drug-induced coma, which is a serious state caused by very low blood sugar unrelated to diabetes. Codes starting with E16 address other pancreatic hormone issues including E16.0 Drug-induced hypoglycemia without coma (also called iatrogenic hypoglycemia), E16.1 Other hypoglycemia which covers functional or familial hyperinsulinism and reactive hypoglycemia, and E16.3 and E16.4 for increased secretion of glucagon and gastrin hormones respectively. These codes assist health professionals in accurately identifying non-diabetic endocrine disorders like Zollinger-Ellison syndrome (gastrinoma), impaired glucose tolerance with hyperinsulinism, and other hormone secretion abnormalities. The unspecified and “other” categories (E16.2, E16.8, E16.9) allow coding for less defined pancreatic secretion disorders or hypoglycemia levels, helping capture a full spectrum of endocrine pancreatic conditions essential for diagnosis and treatment planning.