ICD-10-CM Code E31

Polyglandular dysfunction

Version 2021 Non-Billable Code

Not Valid for Submission

E31 is a "header" nonspecific and non-billable code code, consider using a code with a higher level of specificity for a diagnosis of polyglandular dysfunction. The code is NOT valid for the year 2021 for the submission of HIPAA-covered transactions.

ICD-10:E31
Short Description:Polyglandular dysfunction
Long Description:Polyglandular dysfunction

Consider the following ICD-10 codes with a higher level of specificity:

  • E31.0 - Autoimmune polyglandular failure
  • E31.1 - Polyglandular hyperfunction
  • E31.2 - Multiple endocrine neoplasia [MEN] syndromes
  • E31.20 - Multiple endocrine neoplasia [MEN] syndrome, unspecified
  • E31.21 - Multiple endocrine neoplasia [MEN] type I
  • E31.22 - Multiple endocrine neoplasia [MEN] type IIA
  • E31.23 - Multiple endocrine neoplasia [MEN] type IIB
  • E31.8 - Other polyglandular dysfunction
  • E31.9 - ... unspecified

Tabular List of Diseases and Injuries

The Tabular List of Diseases and Injuries is a list of ICD-10 codes, organized "head to toe" into chapters and sections with guidance for inclusions, exclusions, descriptions and more. The following references are applicable to the code E31:

Type 1 Excludes

Type 1 Excludes
A type 1 excludes note is a pure excludes note. It means "NOT CODED HERE!" An Excludes1 note indicates that the code excluded should never be used at the same time as the code above the Excludes1 note. An Excludes1 is used when two conditions cannot occur together, such as a congenital form versus an acquired form of the same condition.
  • ataxia telangiectasia Louis-Bar G11.3
  • dystrophia myotonica Steinert G71.11
  • pseudohypoparathyroidism E20.1

Code Classification

  • Endocrine, nutritional and metabolic diseases (E00–E90)
    • Disorders of other endocrine glands (E20-E35)
      • Polyglandular dysfunction (E31)

Code History

  • FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016
    (First year ICD-10-CM implemented into the HIPAA code set)
  • FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
  • FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
  • FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
  • FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020
  • FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021

Information for Patients


Endocrine Diseases

Your endocrine system includes eight major glands throughout your body. These glands make hormones. Hormones are chemical messengers. They travel through your bloodstream to tissues or organs. Hormones work slowly and affect body processes from head to toe. These include

  • Growth and development
  • Metabolism - digestion, elimination, breathing, blood circulation and maintaining body temperature
  • Sexual function
  • Reproduction
  • Mood

If your hormone levels are too high or too low, you may have a hormone disorder. Hormone diseases also occur if your body does not respond to hormones the way it is supposed to. Stress, infection and changes in your blood's fluid and electrolyte balance can also influence hormone levels.

In the United States, the most common endocrine disease is diabetes. There are many others. They are usually treated by controlling how much hormone your body makes. Hormone supplements can help if the problem is too little of a hormone.

  • Androgen insensitivity syndrome (Medical Encyclopedia)
  • Endocrine glands (Medical Encyclopedia)
  • Hypogonadotropic hypogonadism (Medical Encyclopedia)
  • Intersex (Medical Encyclopedia)
  • Multiple endocrine neoplasia (MEN) I (Medical Encyclopedia)
  • Multiple endocrine neoplasia (MEN) II (Medical Encyclopedia)
  • Zollinger-Ellison syndrome (Medical Encyclopedia)

[Learn More]