2027 ICD-10-CM Diagnosis Code E31Polyglandular dysfunction

ICD-10-CM Codes›E00–E89›E20-E35›E31

ICD-10-CM E31
CMSSource: CMS FY 2027 ICD-10-CM dataset · Effective Oct 1, 2026 – Sep 30, 2027

E31 is a non-billable ICD-10-CM category code for polyglandular dysfunction, so it cannot be submitted on claims. Use a more specific code from this category instead, such as E31.0, E31.1, E31.20, and E31.21.

Code Identity

ICD-10-CM Code
E31
Billable Status
No — Non-Billable Category
Code Describes
Polyglandular dysfunction
Short Description
Polyglandular dysfunction
Same as the full description in the CMS dataset.
Chapter
E20-E35
Disorders of other endocrine glands

Code Classification

ChapterE00–E89Endocrine, nutritional and metabolic diseases
SectionE20-E35Disorders of other endocrine glands
CategoryE31Polyglandular dysfunction
This CodeE31Polyglandular dysfunction

Specific Coding for Polyglandular dysfunctionOverview

Non-specific codes like E31 require more characters. Use one of these billable codes instead:

  • Use E31.0 for Autoimmune polyglandular failure

  • Use E31.1 for Polyglandular hyperfunction

  • E31.2 for Multiple endocrine neoplasia [MEN] syndromes

  • Use E31.20 for Multiple endocrine neoplasia [MEN] syndrome, unspecified

  • Use E31.21 for Multiple endocrine neoplasia [MEN] type I

  • Use E31.22 for Multiple endocrine neoplasia [MEN] type IIA

  • Use E31.23 for Multiple endocrine neoplasia [MEN] type IIB

  • Use E31.8 for Other polyglandular dysfunction

  • Use E31.9 for Polyglandular dysfunction, unspecified

Instructional NotesGuidance

Instructions from the official ICD-10-CM Tabular List that apply to E31: its own notes plus those printed at block E20-E35 and Chapter 4. A note printed at a category, block or chapter applies to every code under it.

Excludes1

Not coded here: the excluded code is never reported together with this one, unless the two conditions are unrelated.

On E31 itself
  • ataxia telangiectasia [Louis-Bar] (G11.3)
  • dystrophia myotonica [Steinert] (G71.11)
  • pseudohypoparathyroidism (E20.1)
From Block E20-E35 Disorders of other endocrine glands applies to 99 codes
From Chapter 4 (E00-E89) Endocrine, nutritional and metabolic diseases applies to 973 codes
  • transitory endocrine and metabolic disorders specific to newborn (P70-P74)

Notes

General instructions on how these codes are used.

From Chapter 4 (E00-E89) Endocrine, nutritional and metabolic diseases applies to 973 codes
  • All neoplasms, whether functionally active or not, are classified in Chapter 2. Appropriate codes in this chapter (i.e. E05.8, E07.0, E16-E31, E34.-) may be used as additional codes to indicate either functional activity by neoplasms and ectopic endocrine tissue or hyperfunction and hypofunction of endocrine glands associated with neoplasms and other conditions classified elsewhere.

Source: CMS ICD-10-CM Tabular List. How to read instructional notes.

Referenced in Other NotesGuidance

Instructional notes printed at other codes that name E31, its category, or a range that includes it.

Code First 1

These codes say to code first a condition named in the note, and E31 is one of the conditions named.

  • G63 Polyneuropathy in diseases classified elsewhere
    endocrine disease, except diabetes (E00-E07, E15-E16, E20-E34) names E20-E34, which includes this code

Notes 1

These notes mention E31.

  • Chapter 4 (E00-E89) Endocrine, nutritional and metabolic diseases
    All neoplasms, whether functionally active or not, are classified in Chapter 2. Appropriate codes in this chapter (i.e. E05.8, E07.0, E16-E31, E34.-) may be used as additional codes to indicate either functional activity by neoplasms and ectopic endocrine tissue or hyperfunction and hypofunction of endocrine glands associated with neoplasms and other conditions classified elsewhere. names E16-E31, which includes this code

Patient EducationClinical

Endocrine Diseases

Your endocrine system includes eight major glands throughout your body. These glands make hormones. Hormones are chemical messengers. They travel through your bloodstream to tissues or organs. Hormones work slowly and affect body processes from head to toe. These include:

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2026No changes
FY 2027CurrentCurrent code set, no changesEffective October 1, 2026 through September 30, 2027.

Questions About E31Overview

What is the ICD-10 code for polyglandular dysfunction?

E31 is the ICD-10-CM category for polyglandular dysfunction, but it is a non-billable header: claims need a more specific code from this category, listed on this page.

Is E31 (Polyglandular dysfunction) a billable code?

No. This is a category header that groups the codes for polyglandular dysfunction, and headers cannot be submitted on claims. Claims for polyglandular dysfunction need a more specific code from this category, such as E31.0, E31.1, and E31.20.

Can E31 be reported with G11.3?

Not as a rule. The Excludes1 note on E31 lists "ataxia telangiectasia [Louis-Bar] (G11.3)". An Excludes1 note means the excluded code is never reported together with this one; the only exception is when the two conditions are unrelated to each other (Official Guidelines, Section I.A.12.a).