2022 ICD-10-CM Code E31

Polyglandular dysfunction

Version 2021

Not Valid for Submission

ICD-10:E31
Short Description:Polyglandular dysfunction
Long Description:Polyglandular dysfunction

Code Classification

  • Endocrine, nutritional and metabolic diseases (E00–E90)
    • Disorders of other endocrine glands (E20-E35)
      • Polyglandular dysfunction (E31)

E31 is a non-specific and non-billable diagnosis code code, consider using a code with a higher level of specificity for a diagnosis of polyglandular dysfunction. The code is not specific and is NOT valid for the year 2022 for the submission of HIPAA-covered transactions. Category or Header define the heading of a category of codes that may be further subdivided by the use of 4th, 5th, 6th or 7th characters.

Specific Coding for Polyglandular dysfunction

Non-specific codes like E31 require more digits to indicate the appropriate level of specificity. Consider using any of the following ICD-10 codes with a higher level of specificity when coding for polyglandular dysfunction:

  • BILLABLE CODE - Use E31.0 for Autoimmune polyglandular failure
  • BILLABLE CODE - Use E31.1 for Polyglandular hyperfunction
  • NON-BILLABLE CODE - E31.2 for Multiple endocrine neoplasia [MEN] syndromes
  • BILLABLE CODE - Use E31.20 for Multiple endocrine neoplasia [MEN] syndrome, unspecified
  • BILLABLE CODE - Use E31.21 for Multiple endocrine neoplasia [MEN] type I
  • BILLABLE CODE - Use E31.22 for Multiple endocrine neoplasia [MEN] type IIA
  • BILLABLE CODE - Use E31.23 for Multiple endocrine neoplasia [MEN] type IIB
  • BILLABLE CODE - Use E31.8 for Other polyglandular dysfunction
  • BILLABLE CODE - Use E31.9 for Polyglandular dysfunction, unspecified

Tabular List of Diseases and Injuries

The Tabular List of Diseases and Injuries is a list of ICD-10 codes, organized "head to toe" into chapters and sections with coding notes and guidance for inclusions, exclusions, descriptions and more. The following references are applicable to the code E31:


Type 1 Excludes

Type 1 Excludes
A type 1 excludes note is a pure excludes note. It means "NOT CODED HERE!" An Excludes1 note indicates that the code excluded should never be used at the same time as the code above the Excludes1 note. An Excludes1 is used when two conditions cannot occur together, such as a congenital form versus an acquired form of the same condition.

Information for Patients


Endocrine Diseases

Your endocrine system includes eight major glands throughout your body. These glands make hormones. Hormones are chemical messengers. They travel through your bloodstream to tissues or organs. Hormones work slowly and affect body processes from head to toe. These include

If your hormone levels are too high or too low, you may have a hormone disorder. Hormone diseases also occur if your body does not respond to hormones the way it is supposed to. Stress, infection and changes in your blood's fluid and electrolyte balance can also influence hormone levels.

In the United States, the most common endocrine disease is diabetes. There are many others. They are usually treated by controlling how much hormone your body makes. Hormone supplements can help if the problem is too little of a hormone.


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Code History

  • FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021
  • FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020
  • FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
  • FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
  • FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
  • FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016 (First year ICD-10-CM implemented into the HIPAA code set)