2026 ICD-10-CM Diagnosis Code E31Polyglandular dysfunction

ICD-10-CM Codes›E00–E89›E20-E35›E31

ICD-10-CM E31
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

E31 is a non-billable ICD-10-CM category code for polyglandular dysfunction, so it cannot be submitted on claims. Use a more specific code from this category instead, such as E31.0, E31.1, E31.20, and E31.21.

Code Identity

ICD-10-CM Code
E31
Billable Status
No — Non-Billable Category
Code Describes
Polyglandular dysfunction
Chapter
E20-E35
Disorders of other endocrine glands

Code Classification

ChapterE00–E89Endocrine, nutritional and metabolic diseases
SectionE20-E35Disorders of other endocrine glands
CategoryE31Polyglandular dysfunction
This CodeE31Polyglandular dysfunction

Specific Coding for Polyglandular dysfunctionOverview

Non-specific codes like E31 require more characters. Use one of these billable codes instead:

  • Use E31.0 for Autoimmune polyglandular failure

  • Use E31.1 for Polyglandular hyperfunction

  • E31.2 for Multiple endocrine neoplasia [MEN] syndromes

  • Use E31.20 for Multiple endocrine neoplasia [MEN] syndrome, unspecified

  • Use E31.21 for Multiple endocrine neoplasia [MEN] type I

  • Use E31.22 for Multiple endocrine neoplasia [MEN] type IIA

  • Use E31.23 for Multiple endocrine neoplasia [MEN] type IIB

  • Use E31.8 for Other polyglandular dysfunction

  • Use E31.9 for Polyglandular dysfunction, unspecified

Tabular List NotesGuidance

Coding notes and annotation back-references applicable to this code.

Type 1 Excludes

  • ataxia telangiectasia Louis-Bar G11.3
  • dystrophia myotonica Steinert G71.11
  • pseudohypoparathyroidism E20.1

Patient EducationClinical

Endocrine Diseases

Your endocrine system includes eight major glands throughout your body. These glands make hormones. Hormones are chemical messengers. They travel through your bloodstream to tissues or organs. Hormones work slowly and affect body processes from head to toe. These include:

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About E31Overview

Is E31 (Polyglandular dysfunction) a billable code?

No. This is a category header that groups the codes for polyglandular dysfunction, and headers cannot be submitted on claims. Claims for polyglandular dysfunction need a more specific code from this category, such as E31.0, E31.1, and E31.20.