2026 ICD-10-CM Diagnosis Code E88.02Plasminogen deficiency

ICD-10-CM Codes›E00–E89›E70-E88›E88

ICD-10-CM E88.02
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

E88.02 is a billable ICD-10-CM diagnosis code for plasminogen deficiency. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 826 through 830, 843 through 845. Coders also document this condition as dysplasminogenemia. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Other specified and unspecified nutritional and metabolic disorders.

Code Identity

ICD-10-CM Code
E88.02
Billable Status
Yes — Valid for Submission
Code Describes
Plasminogen deficiency
Short Description
Plasminogen deficiency
Same as the full description in the CMS dataset.
Parent Code
E88.0
Disorders of plasma-protein metabolism, not elsewhere classified

Code Classification

ChapterE00–E89Endocrine, nutritional and metabolic diseases
SectionE70-E88Metabolic disorders
CategoryE88Other and unspecified metabolic disorders
This CodeE88.02Plasminogen deficiency

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Dysplasminogenemia
  • Fibrinolytic bleeding syndrome
  • Hypoplasminogenemia

Tabular List NotesGuidance

Coding notes and annotation back-references applicable to this code.

Inclusion Terms

  • Dysplasminogenemia
  • Hypoplasminogenemia
  • Type 1 plasminogen deficiency
  • Type 2 plasminogen deficiency

Code Also

  • , if applicable, ligneous conjunctivitis H10.51

Use Additional Code

  • code for associated findings, such as:
  • hydrocephalus G91.4
  • otitis media H67
  • respiratory disorder related to plasminogen deficiency J99

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Deficiency, deficient
      • plasminogen (type 1) (type 2)
    • Dysplasminogenemia
    • Hypoplasminogenemia

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR END016
Other specified and unspecified nutritional and metabolic disorders
Default principal diagnosis: inpatient Yes · outpatient Yes

Patient EducationClinical

Bleeding Disorders

Normally, if you get hurt, your body forms a blood clot to stop the bleeding. For blood to clot, your body needs cells called platelets and proteins known as clotting factors. If you have a bleeding disorder, you either do not have enough platelets or clotting factors or they don't work the way they should.

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Code History & ChangesHistory

Replacement E88.02 replaces the following previously assigned code(s):

  • E88.09 - Oth disorders of plasma-protein metabolism, NEC
FY 2019AddedAdded to the ICD-10-CM code setEffective October 1, 2018.
FY 2020–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About E88.02Overview

Is E88.02 a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report plasminogen deficiency on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What MS-DRG does E88.02 group to?

When plasminogen deficiency is the principal diagnosis on an inpatient stay, it groups to MS-DRG 826, 827, 828, 829, 830, 843, 844, 845, with relative weights from 0.8516 to 4.6778 depending on complications. Higher weights mean higher Medicare reimbursement.

Footnotes

[1] Chronic - a chronic condition code indicates a condition lasting 12 months or longer and its effect on the patient based on one or both of the following criteria:

  • The condition results in the need for ongoing intervention with medical products,treatment, services, and special equipment
  • The condition places limitations on self-care, independent living, and social interactions.