MS-DRG · FY 2026 v43.0
MS-DRG 843 – Other Myeloproliferative Disorders or Poorly Differentiated Neoplastic Diagnoses with MCC
A Medical DRG in MDC 17 (Myeloproliferative Diseases & Disorders, Poorly Differentiated Neoplasms). Inpatient cases group to DRG 843 when the ICD-10-CM principal diagnosis is one of the 109 codes listed below and a secondary diagnosis on the major complication or comorbidity (MCC) list is present. Its FY 2026 relative weight is 1.9948 with a geometric mean length of stay of 5.4 days.
Medical DRG – assigned by principal diagnosis✓ Official CMS v43.0 dataset
1.9948
Relative Weight
5.4
Geometric Mean LOS (days)
7.5
Arithmetic Mean LOS (days)
109
Principal Diagnosis Codes
Severity family
DRG 843with MCCWeight 1.9948 · GMLOS 5.4 daysDRG 844with CCWeight 1.2174 · GMLOS 3.7 daysDRG 845without CC/MCCWeight 0.8516 · GMLOS 2.4 days
How a case is assigned to DRG 843
The grouper first assigns the case to MDC 17 from the principal diagnosis and finds no qualifying operating-room procedure (this is a Medical DRG; ICD-10-PCS codes do not drive assignment here), then applies the severity split from secondary diagnoses: with MCC → 843; with CC → 844; without CC/MCC → 845.
ICD-10-CM
Principal Diagnosis Codes 109 codes · 19 categories
109 of 109 shown
C37 Malignant neoplasm of thymus1 code
- C37 Malignant neoplasm of thymus
C48 Malignant neoplasm of retroperitoneum and peritoneum1 code
- C48.0 Malignant neoplasm of retroperitoneum
C76 Malignant neoplasm of other and ill-defined sites7 codes
- C76.40 Malignant neoplasm of unspecified upper limb
- C76.41 Malignant neoplasm of right upper limb
- C76.42 Malignant neoplasm of left upper limb
- C76.50 Malignant neoplasm of unspecified lower limb
- C76.51 Malignant neoplasm of right lower limb
- C76.52 Malignant neoplasm of left lower limb
- C76.8 Malignant neoplasm of other specified ill-defined sites
C79 Secondary malignant neoplasm of other and unspecified sites2 codes
C7A Malignant neuroendocrine tumors5 codes
C7B Secondary neuroendocrine tumors4 codes
C80 Malignant neoplasm without specification of site3 codes
C96 Other and unspecified malignant neoplasms of lymphoid, hematopoietic and related tissue1 code
- C96.0 Multifocal and multisystemic (disseminated) Langerhans-cell histiocytosis
D09 Carcinoma in situ of other and unspecified sites3 codes
D19 Benign neoplasm of mesothelial tissue2 codes
D36 Benign neoplasm of other and unspecified sites2 codes
D3A Benign neuroendocrine tumors3 codes
D48 Neoplasm of uncertain behavior of other and unspecified sites2 codes
D49 Neoplasms of unspecified behavior3 codes
E88 Other and unspecified metabolic disorders2 codes
Q85 Phakomatoses, not elsewhere classified5 codes
Z85 Personal history of malignant neoplasm60 codes
- Z85.00 Personal history of malignant neoplasm of unspecified digestive organ
- Z85.01 Personal history of malignant neoplasm of esophagus
- Z85.020 Personal history of malignant carcinoid tumor of stomach
- Z85.028 Personal history of other malignant neoplasm of stomach
- Z85.030 Personal history of malignant carcinoid tumor of large intestine
- Z85.038 Personal history of other malignant neoplasm of large intestine
- Z85.040 Personal history of malignant carcinoid tumor of rectum
- Z85.048 Personal history of other malignant neoplasm of rectum, rectosigmoid junction, and anus
- Z85.05 Personal history of malignant neoplasm of liver
- Z85.060 Personal history of malignant carcinoid tumor of small intestine
- Z85.068 Personal history of other malignant neoplasm of small intestine
- Z85.07 Personal history of malignant neoplasm of pancreas
- Z85.09 Personal history of malignant neoplasm of other digestive organs
- Z85.110 Personal history of malignant carcinoid tumor of bronchus and lung
- Z85.118 Personal history of other malignant neoplasm of bronchus and lung
- Z85.12 Personal history of malignant neoplasm of trachea
- Z85.20 Personal history of malignant neoplasm of unspecified respiratory organ
- Z85.21 Personal history of malignant neoplasm of larynx
- Z85.22 Personal history of malignant neoplasm of nasal cavities, middle ear, and accessory sinuses
- Z85.230 Personal history of malignant carcinoid tumor of thymus
- Z85.238 Personal history of other malignant neoplasm of thymus
- Z85.29 Personal history of malignant neoplasm of other respiratory and intrathoracic organs
- Z85.3 Personal history of malignant neoplasm of breast
- Z85.40 Personal history of malignant neoplasm of unspecified female genital organ
- Z85.41 Personal history of malignant neoplasm of cervix uteri
- Z85.42 Personal history of malignant neoplasm of other parts of uterus
- Z85.43 Personal history of malignant neoplasm of ovary
- Z85.44 Personal history of malignant neoplasm of other female genital organs
- Z85.45 Personal history of malignant neoplasm of unspecified male genital organ
- Z85.46 Personal history of malignant neoplasm of prostate
- Z85.47 Personal history of malignant neoplasm of testis
- Z85.48 Personal history of malignant neoplasm of epididymis
- Z85.49 Personal history of malignant neoplasm of other male genital organs
- Z85.4A Personal history of malignant neoplasm of fallopian tube(s)
- Z85.50 Personal history of malignant neoplasm of unspecified urinary tract organ
- Z85.51 Personal history of malignant neoplasm of bladder
- Z85.520 Personal history of malignant carcinoid tumor of kidney
- Z85.528 Personal history of other malignant neoplasm of kidney
- Z85.53 Personal history of malignant neoplasm of renal pelvis
- Z85.54 Personal history of malignant neoplasm of ureter
- Z85.59 Personal history of malignant neoplasm of other urinary tract organ
- Z85.6 Personal history of leukemia
- Z85.71 Personal history of Hodgkin lymphoma
- Z85.72 Personal history of non-Hodgkin lymphomas
- Z85.79 Personal history of other malignant neoplasms of lymphoid, hematopoietic and related tissues
- Z85.810 Personal history of malignant neoplasm of tongue
- Z85.818 Personal history of malignant neoplasm of other sites of lip, oral cavity, and pharynx
- Z85.819 Personal history of malignant neoplasm of unspecified site of lip, oral cavity, and pharynx
- Z85.820 Personal history of malignant melanoma of skin
- Z85.821 Personal history of Merkel cell carcinoma
- Z85.828 Personal history of other malignant neoplasm of skin
- Z85.830 Personal history of malignant neoplasm of bone
- Z85.831 Personal history of malignant neoplasm of soft tissue
- Z85.840 Personal history of malignant neoplasm of eye
- Z85.841 Personal history of malignant neoplasm of brain
- Z85.848 Personal history of malignant neoplasm of other parts of nervous tissue
- Z85.850 Personal history of malignant neoplasm of thyroid
- Z85.858 Personal history of malignant neoplasm of other endocrine glands
- Z85.89 Personal history of malignant neoplasm of other organs and systems
- Z85.9 Personal history of malignant neoplasm, unspecified
Z87 Personal history of other diseases and conditions1 code
- Z87.410 Personal history of cervical dysplasia
ICD-10-PCS
Procedure Codes
Procedure codes do not drive assignment for this DRG. DRG 843 is a Medical DRG, assigned from the principal diagnosis above.
Frequently Asked Questions
What is MS-DRG 843?
MS-DRG 843 (Other Myeloproliferative Disorders or Poorly Differentiated Neoplastic Diagnoses with MCC) is a medical DRG in MDC 17 (Myeloproliferative Diseases & Disorders, Poorly Differentiated Neoplasms). Its FY 2026 relative weight is 1.9948 with a geometric mean length of stay of 5.4 days.
What is the difference between DRG 843, 844, 845?
All 3 share the same base category; the severity of secondary diagnoses separates them: 843 (with MCC), 844 (with CC), 845 (without CC/MCC). A major complication or comorbidity (MCC) places the case in the highest-weighted DRG of the family; a CC in the middle; neither in the lowest.
How many diagnosis codes group to DRG 843?
109 ICD-10-CM principal diagnosis codes group to this DRG, spanning 19 three-character categories.
What is the relative weight of DRG 843?
The FY 2026 relative weight of this DRG is 1.9948, meaning reimbursement of roughly 1.99 times the average Medicare inpatient case. Multiply by a hospital's blended base rate for the approximate payment.
← PreviousDRG 842 – Lymphoma and Non-Acute Leukemia without CC/MCCNext →DRG 844 – Other Myeloproliferative Disorders or Poorly Differentiated
Source: CMS ICD-10 MS-DRG v43.0 Definitions Manual and the FY 2026 IPPS Final Rule (Table 5), effective October 1, 2025 through September 30, 2026. We publish the DRG assignments as CMS defines them and add the navigation, search, and code links.
