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  6. 2025 ICD-10-CM Code R77

2025 ICD-10-CM Diagnosis Code R77

Other abnormalities of plasma proteins

ICD-10-CM Code:
R77
ICD-10 Code for:
Other abnormalities of plasma proteins
Is Billable?
Not Valid for Submission
Code Navigator:

R77 is a non-specific and non-billable diagnosis code code, consider using a code with a higher level of specificity for a diagnosis of other abnormalities of plasma proteins. The code is not specific and is NOT valid for the year 2025 for the submission of HIPAA-covered transactions. Category or Header define the heading of a category of codes that may be further subdivided by the use of 4th, 5th, 6th or 7th characters.

According to ICD-10-CM guidelines this code should not to be used as a principal diagnosis code when a related definitive diagnosis has been established.

Specific Coding Applicable to Other abnormalities of plasma proteins

Non-specific codes like R77 require more digits to indicate the appropriate level of specificity. Consider using any of the following ICD-10-CM codes with a higher level of specificity when coding for other abnormalities of plasma proteins:

  • Use R77.0 for Abnormality of albumin - BILLABLE CODE

  • Use R77.1 for Abnormality of globulin - BILLABLE CODE

  • Use R77.2 for Abnormality of alphafetoprotein - BILLABLE CODE

  • Use R77.8 for Other specified abnormalities of plasma proteins - BILLABLE CODE

  • Use R77.9 for Abnormality of plasma protein, unspecified - BILLABLE CODE

Code Classification

  • Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
    R00–R99
    • Abnormal findings on examination of blood, without diagnosis
      R70-R79
      • Other abnormalities of plasma proteins
        R77

Tabular List of Diseases and Injuries

The following annotation back-references are applicable to this diagnosis code. The Tabular List of Diseases and Injuries is a list of ICD-10-CM codes, organized "head to toe" into chapters and sections with coding notes and guidance for inclusions, exclusions, descriptions and more.


Type 1 Excludes

Type 1 Excludes
A type 1 excludes note is a pure excludes note. It means "NOT CODED HERE!" An Excludes1 note indicates that the code excluded should never be used at the same time as the code above the Excludes1 note. An Excludes1 is used when two conditions cannot occur together, such as a congenital form versus an acquired form of the same condition.
  • disorders of plasma-protein metabolism E88.0

Patient Education


Blood

Your blood is made up of liquid and solids. The liquid part, called plasma, is made of water, salts, and protein. Over half of your blood is plasma. The solid part of your blood contains red blood cells, white blood cells, and platelets.

Red blood cells (RBC) deliver oxygen from your lungs to your tissues and organs. White blood cells (WBC) fight infection and are part of your immune system. Platelets help blood to clot when you have a cut or wound. Bone marrow, the spongy material inside your bones, makes new blood cells. Blood cells constantly die and your body makes new ones. Red blood cells live about 120 days, and platelets live about 6 days. Some white blood cells live less than a day, but others live much longer.

There are four blood types: A, B, AB, or O. Also, blood is either Rh-positive or Rh-negative. So if you have type A blood, it's either A positive or A negative. Which type you are is important if you need a blood transfusion. And your Rh factor could be important if you become pregnant - an incompatibility between your type and the baby's could create problems.

Blood tests such as blood count tests help doctors check for certain diseases and conditions. They also help check the function of your organs and show how well treatments are working. Problems with your blood may include bleeding disorders, excessive clotting and platelet disorders. If you lose too much blood, you may need a transfusion.

NIH: National Heart, Lung, and Blood Institute


[Learn More in MedlinePlus]

Code History

  • FY 2024 - No Change, effective from 10/1/2023 through 9/30/2024
  • FY 2023 - No Change, effective from 10/1/2022 through 9/30/2023
  • FY 2022 - No Change, effective from 10/1/2021 through 9/30/2022
  • FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021
  • FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020
  • FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
  • FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
  • FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
  • FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016. This was the first year ICD-10-CM was implemented into the HIPAA code set.