2026 ICD-10-CM Diagnosis Code E34.9Endocrine disorder, unspecified

ICD-10-CM Codes›E00–E89›E20-E35›E34

ICD-10-CM E34.9
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

E34.9 is a billable ICD-10-CM diagnosis code for endocrine disorder, unspecified. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 643 through 645. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Other specified and unspecified endocrine disorders.

Code Identity

ICD-10-CM Code
E34.9
Billable Status
Yes — Valid for Submission
Code Describes
Endocrine disorder, unspecified
Short Description
Endocrine disorder, unspecified
Same as the full description in the CMS dataset.
Parent Code
E34
Other endocrine disorders

Code Classification

ChapterE00–E89Endocrine, nutritional and metabolic diseases
SectionE20-E35Disorders of other endocrine glands
CategoryE34Other endocrine disorders
This CodeE34.9Endocrine disorder, unspecified

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Abnormal hormonal requirement
  • Abnormal hormone production
  • Abnormal hormone secretion
  • Acute confusional state, of endocrine origin
  • Adult osteomalacia due to endocrine disease
  • Alopecia, progressive neurological defect, endocrinopathy syndrome
  • Anemia of endocrine disorder
  • Arthropathy associated with an endocrine AND/OR metabolic disorder
  • Arthropathy due to endocrine disorder
  • Autonomic neuropathy due to endocrine disease
  • Benign intracranial hypertension
  • Benign intracranial hypertension due to endocrine disease
  • Chorea due to endocrine disorder
  • Combination of endocrine dysfunction
  • Decreased hormonal activity
  • Decreased hormone production
  • Decreased hormone secretion
  • Disorder of endocrine receptor
  • Disorder of endocrine system
  • Endocrine disease treatment started
  • Endocrine disorder monitoring status
  • Endocrine disorder related to puberty
  • Endocrine female infertility
  • Endocrine menstrual disturbance
  • Endocrine myopathy
  • Endocrine symptom change
  • Endocrine system complication of procedure
  • Epiphyseal arrest due to disorder of endocrine system
  • Erectile dysfunction due to endocrine disease
  • Erythrocytosis due to endocrine disorder
  • Functional disease of the CNS with neuroendocrine disturbance
  • Glaucoma in endocrine, nutritional and metabolic diseases
  • Hereditary disorder of endocrine system
  • Hormonal activity
  • Hormonal requirement
  • Hormonal resistance
  • Hypermelanosis due to endocrine disorder
  • Hypermelanosis due to hormonal factor
  • Hypertension secondary to endocrine disorder
  • Impaired glucose tolerance associated with hormonal etiology
  • Inappropriate hormone secretion
  • Inappropriate secondary erythrocytosis
  • Increased hormonal activity
  • Increased hormone production
  • Increased hormone secretion
  • Infantile multisystem neurologic, endocrine, pancreatic disease
  • Intellectual disability, myopathy, short stature, endocrine defect syndrome
  • Isolated deficiency of hormone other than HGH
  • Lymphedema due to endocrine disease
  • Multiple endocrine deficiency syndrome
  • Neuropathy associated with endocrine disorder
  • Obesity due to leptin receptor gene deficiency
  • Optic nerve hypoplasia due to endocrine deficiency
  • Osteoporosis due to endocrine disorder
  • Pancreatic insufficiency
  • POEMS syndrome
  • Polyendocrine polyneuropathy syndrome
  • Psychogenic endocrine malfunction
  • Sequelae of endocrine disorders
  • Severe obesity

Tabular List NotesGuidance

Coding notes and annotation back-references applicable to this code.

Inclusion Terms

  • Endocrine disturbance NOS
  • Hormone disturbance NOS

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Arthritis, arthritic(acute) (chronic) (nonpyogenic) (subacute)
      • in (due to)
        • endocrine disorder NEC
    • Arthropathy
      • in (due to)
        • endocrine disease NOS
    • Cataract(cortical) (immature) (incipient)
      • in (due to)
        • endocrine disease
    • Complication(s) (from) (of)
      • endocrine
    • Deficiency, deficient
      • endocrine
    • Disease, diseased
      • ductless glands
    • Disease, diseased
      • endocrine glands or system NEC
    • Disorder(of)
      • endocrine
    • Disturbance(s)
      • endocrine (gland)
    • Disturbance(s)
      • hormones
    • Dysendocrinism
    • Dysfunction
      • endocrine NOS
    • Dysfunction
      • gland, glandular NOS
    • Glaucoma
      • in (due to)
        • endocrine disease NOS
    • Imbalance
      • endocrine
    • Imbalance
      • hormone
    • Myopathy
      • endocrine NEC
    • Myopathy
      • in (due to)
        • endocrine disease NEC
    • Neuropathy, neuropathic
      • peripheral (nerve)
        • autonomic
          • in (due to)
            • endocrine disease NEC
    • Polyneuropathy(peripheral)
      • in (due to)
        • endocrine disease NEC
    • Syndrome
      • myasthenic
        • in
          • endocrine disease NEC

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR END015
Other specified and unspecified endocrine disorders
Default principal diagnosis: inpatient Yes · outpatient Yes

Clinical InformationClinical

  • POEMS Syndrome

    a multisystemic disorder characterized by a sensorimotor polyneuropathy (polyneuropathies), organomegaly, endocrinopathy, monoclonal gammopathy, and pigmentary skin changes. other clinical features which may be present include edema; cachexia; microangiopathic glomerulopathy; pulmonary hypertension (hypertension, pulmonary); cutaneous necrosis; thrombocytosis; and polycythemia. this disorder is frequently associated with osteosclerotic myeloma. (from adams et al., principles of neurology, 6th ed, p1335; rev med interne 1997;18(7):553-62)

Patient EducationClinical

Endocrine Diseases

Your endocrine system includes eight major glands throughout your body. These glands make hormones. Hormones are chemical messengers. They travel through your bloodstream to tissues or organs. Hormones work slowly and affect body processes from head to toe. These include:

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert E34.9 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
259.9 Endocrine disorder NOS
Approximate The match is approximate rather than exact.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About E34.9Overview

Is E34.9 (Other endocrine disorders) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report endocrine disorder, unspecified on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What MS-DRG does E34.9 group to?

When endocrine disorder, unspecified is the principal diagnosis on an inpatient stay, it groups to MS-DRG 643, 644, 645, with relative weights from 0.7683 to 1.6461 depending on complications. Higher weights mean higher Medicare reimbursement.

What is the ICD-9 equivalent of E34.9?

Under the General Equivalence Mappings, endocrine disorder, unspecified converts to ICD-9-CM 259.9 (endocrine disorder NOS). The mapping is approximate, so confirm the match fits the documentation.

Footnotes

[1] Not chronic - A diagnosis code that does not fit the criteria for chronic condition (duration, ongoing medical treatment, and limitations) is considered not chronic. Some codes designated as not chronic are acute conditions. Other diagnosis codes that indicate a possible chronic condition, but for which the duration of the illness is not specified in the code description (i.e., we do not know the condition has lasted 12 months or longer) also are considered not chronic.