1. Home
  2. ICD-10-CM Codes List
  3. E00–E89
  4. E20-E35
  5. Ovarian dysfunction (E28)

Ovarian dysfunction (E28)

ICD-10 code E28 covers a range of ovarian dysfunction disorders, including conditions of hormone imbalance, structural ovarian issues, and premature ovarian failure. These codes help specify diagnoses such as estrogen or androgen excess, polycystic ovarian syndrome, and various types of ovarian failure.

Medical coders use the ICD-10 code for ovarian dysfunction to classify disorders characterized by abnormal ovarian hormone production or function. For example, E28.0 identifies estrogen excess, also known as hyperestrogenism, while E28.1 codes for androgen excess, sometimes referred to as hyperandrogenization syndrome or ovarian hyperfunction. Polycystic ovarian syndrome (PCOS), a common endocrine disorder with symptoms like ovarian cysts and hormone-related hair loss, is captured by E28.2. Primary ovarian failure and its premature variants, including symptomatic and asymptomatic premature menopause, fall under E28.3 and its subcodes. Other less common or unspecified ovarian dysfunctions, such as ovarian hyperthecosis or diminished ovarian reserve, are classified under E28.8 and E28.9. Using these codes ensures precise documentation of specific ovarian conditions important for diagnosis, treatment, and research.

Instructional Notations

Type 1 Excludes

A type 1 excludes note is a pure excludes note. It means "NOT CODED HERE!" An Excludes1 note indicates that the code excluded should never be used at the same time as the code above the Excludes1 note. An Excludes1 is used when two conditions cannot occur together, such as a congenital form versus an acquired form of the same condition.

  • isolated gonadotropin deficiency E23.0
  • postprocedural ovarian failure E89.4

Clinical Terms

The following clinical terms provide additional context, helping users better understand the clinical background and common associations for each diagnosis listed in this section. Including related terms alongside ICD-10-CM codes supports coders, billers, and healthcare professionals in improving accuracy, enhancing documentation, and facilitating research or patient education.

Eunuchism

The state of being a eunuch, a male without TESTES or whose testes failed to develop. It is characterized by the lack of mature male GERM CELLS and TESTICULAR HORMONES.

Hypogonadism

Condition resulting from deficient gonadal functions, such as GAMETOGENESIS and the production of GONADAL STEROID HORMONES. It is characterized by delay in GROWTH, germ cell maturation, and development of secondary sex characteristics. Hypogonadism can be due to a deficiency of GONADOTROPINS (hypogonadotropic hypogonadism) or due to primary gonadal failure (hypergonadotropic hypogonadism).

Kallmann Syndrome

A genetically heterogeneous disorder caused by hypothalamic GNRH deficiency and OLFACTORY NERVE defects. It is characterized by congenital HYPOGONADOTROPIC HYPOGONADISM and ANOSMIA, possibly with additional midline defects. It can be transmitted as an X-linked (GENETIC DISEASES, X-LINKED), an autosomal dominant, or an autosomal recessive trait.

Polycystic Ovary Syndrome

A complex disorder characterized by infertility, HIRSUTISM; OBESITY; and various menstrual disturbances such as OLIGOMENORRHEA; AMENORRHEA; ANOVULATION. Polycystic ovary syndrome is usually associated with bilateral enlarged ovaries studded with atretic follicles, not with cysts. The term, polycystic ovary, is misleading.

Prune Belly Syndrome

A syndrome characterized by abdominal wall musculature deficiency, cryptorchism, and urinary tract abnormalities. The syndrome derives its name from its characteristic distended abdomen with wrinkled skin.

Spinocerebellar Degenerations

A heterogenous group of degenerative syndromes marked by progressive cerebellar dysfunction either in isolation or combined with other neurologic manifestations. Sporadic and inherited subtypes occur. Inheritance patterns include autosomal dominant, autosomal recessive, and X-linked.