Ovarian dysfunction (E28) ICD-10-CM
The E28 code range covers ovarian dysfunction with 11 ICD-10-CM diagnosis codes. 8 of them are billable and valid for claim submission in fiscal year 2027, and the category headers group them but cannot themselves be billed.
Type 1 Excludes
A type 1 excludes note is a pure excludes note. It means "NOT CODED HERE!" An Excludes1 note indicates that the code excluded should never be used at the same time as the code above the Excludes1 note. An Excludes1 is used when two conditions cannot occur together, such as a congenital form versus an acquired form of the same condition.
Codes in the E28 Range 11 codes · 8 billable
- E28 Ovarian dysfunctionNon-billable
- E28.0 Estrogen excess
- E28.1 Androgen excess
- E28.2 Polycystic ovarian syndrome
- E28.3 Primary ovarian failureNon-billable
- E28.31 Premature menopauseNon-billable
- E28.310 Symptomatic premature menopause
- E28.319 Asymptomatic premature menopause
- E28.39 Other primary ovarian failure
- E28.8 Other ovarian dysfunction
- E28.9 Ovarian dysfunction, unspecified
Clinical Terms in This Code Range
Definitions from the National Library of Medicine for conditions coded in the E28 range.
Androgen Excess
Excessive secretion of androgens from the adrenal glands or gonads. Clinical manifestations may include virilization.
Hyperestrogenism
Abnormally high level of estrogen.
Menopause, Premature
The premature cessation of menses (MENSTRUATION) when the last menstrual period occurs in a woman under the age of 40. It is due to the depletion of OVARIAN FOLLICLES. Premature MENOPAUSE can be caused by diseases; OVARIECTOMY; RADIATION; chemicals; and chromosomal abnormalities.
Polycystic Ovary Syndrome
A complex disorder characterized by infertility, HIRSUTISM; OBESITY; and various menstrual disturbances such as OLIGOMENORRHEA; AMENORRHEA; ANOVULATION. Polycystic ovary syndrome is usually associated with bilateral enlarged ovaries studded with atretic follicles, not with cysts. The term, polycystic ovary, is misleading.
Primary Ovarian Failure
Absent or premature cessation of ovarian function due to a pathologic process originating within the ovaries.
About the E28 Code Range
Ovarian dysfunction means the ovaries are not functioning normally. This category sits within disorders of endocrine glands.
The subdivisions distinguish excess estrogen (E28.0), excess androgen (E28.1), polycystic ovarian syndrome (E28.2), and primary ovarian failure (E28.3). Within primary ovarian failure, premature menopause separates into symptomatic and asymptomatic forms; other primary ovarian failure has its own subdivision. The remaining codes distinguish other ovarian dysfunction from ovarian dysfunction that is unspecified.
Questions About This Page
How many billable codes are in the E28 range?
Of the 11 codes in this range, 8 are billable and valid for claim submission from October 1, 2026 through September 30, 2027. Category header codes group them but cannot be reported on claims.
What does the E28 range classify?
The range classifies ovarian dysfunction. Each code links to its own reference page with billing status, MS-DRG grouping, coding notes, and clinical information.
Related References
Source: CMS FY 2027 ICD-10-CM Tabular List and order file, effective October 1, 2026 through September 30, 2027.
