Other endocrine disorders (E34)
Clinical Information
Androgen-Insensitivity Syndrome - A disorder of sexual development transmitted as an X-linked recessive trait. These patients have a karyotype of 46,XY with end-organ resistance to androgen due to mutations in the androgen receptor (RECEPTORS, ANDROGEN) gene. Severity of the defect in receptor quantity or quality correlates with their phenotypes. In these genetic males, the phenotypic spectrum ranges from those with normal female external genitalia, through those with genital ambiguity as in Reifenstein Syndrome, to that of a normal male with INFERTILITY.
Carcinoid Heart Disease - Cardiac manifestation of gastrointestinal CARCINOID TUMOR that metastasizes to the liver. Substances secreted by the tumor cells, including SEROTONIN, promote fibrous plaque formation in ENDOCARDIUM and its underlying layers. These deposits cause distortion of the TRICUSPID VALVE and the PULMONARY VALVE eventually leading to STENOSIS and valve regurgitation.
Feminization - Development of female secondary SEX CHARACTERISTICS in the MALE. It is due to the effects of estrogenic metabolites of precursors from endogenous or exogenous sources, such as ADRENAL GLANDS or therapeutic drugs.
General Adaptation Syndrome - The sum of all nonspecific systemic reactions of the body to long-continued exposure to systemic stress.
Insulin Resistance - Diminished effectiveness of INSULIN in lowering blood sugar levels: requiring the use of 200 units or more of insulin per day to prevent HYPERGLYCEMIA or KETOSIS.
Metabolic Syndrome - A cluster of symptoms that are risk factors for CARDIOVASCULAR DISEASES and TYPE 2 DIABETES MELLITUS. The major components of metabolic syndrome include ABDOMINAL OBESITY; atherogenic DYSLIPIDEMIA; HYPERTENSION; HYPERGLYCEMIA; INSULIN RESISTANCE; a proinflammatory state; and a prothrombotic (THROMBOSIS) state.
Moyamoya Disease - A noninflammatory, progressive occlusion of the intracranial CAROTID ARTERIES and the formation of netlike collateral arteries arising from the CIRCLE OF WILLIS. Cerebral angiogram shows the puff-of-smoke (moyamoya) collaterals at the base of the brain. It is characterized by endothelial HYPERPLASIA and FIBROSIS with thickening of arterial walls. This disease primarily affects children but can also occur in adults.
POEMS Syndrome - A multisystemic disorder characterized by a sensorimotor polyneuropathy (POLYNEUROPATHIES), organomegaly, endocrinopathy, monoclonal gammopathy, and pigmentary skin changes. Other clinical features which may be present include EDEMA; CACHEXIA; microangiopathic glomerulopathy; pulmonary hypertension (HYPERTENSION, PULMONARY); cutaneous necrosis; THROMBOCYTOSIS; and POLYCYTHEMIA. This disorder is frequently associated with osteosclerotic myeloma. (From Adams et al., Principles of Neurology, 6th ed, p1335; Rev Med Interne 1997;18(7):553-62)
Werner Syndrome - An autosomal recessive disorder that causes premature aging in adults, characterized by sclerodermal skin changes, cataracts, subcutaneous calcification, muscular atrophy, a tendency to diabetes mellitus, aged appearance of the face, baldness, and a high incidence of neoplastic disease.
Werner Syndrome Helicase - A DNA-dependent helicase and 3'-5' exonuclease. It has 3'->5' exonuclease activity towards double-stranded DNA with a 5'-overhang and binds preferentially to DNA substrates containing alternate secondary structures, such as replication forks and HOLLIDAY JUNCTIONS. Mutations in the WRN gene are associated with WERNER SYNDROME.
Instructional Notations
Type 1 Excludes
A type 1 excludes note is a pure excludes note. It means "NOT CODED HERE!" An Excludes1 note indicates that the code excluded should never be used at the same time as the code above the Excludes1 note. An Excludes1 is used when two conditions cannot occur together, such as a congenital form versus an acquired form of the same condition.
- pseudohypoparathyroidism E20.1
Endocrine, nutritional and metabolic diseases (E00–E89)
Disorders of other endocrine glands (E20-E35)
E34 Other endocrine disorders
- E34.0 Carcinoid syndrome
- E34.1 Other hypersecretion of intestinal hormones
- E34.2 Ectopic hormone secretion, not elsewhere classified
E34.3 Short stature due to endocrine disorder
- E34.30 Short stature due to endocrine disorder, unspecified
- E34.31 Constitutional short stature
E34.32 Genetic causes of short stature
- E34.321 Primary insulin-like growth factor-1 (IGF-1) deficiency
- E34.322 Insulin-like growth factor-1 (IGF-1) resistance
- E34.328 Other genetic causes of short stature
- E34.329 Unspecified genetic causes of short stature
- E34.39 Other short stature due to endocrine disorder
- E34.4 Constitutional tall stature
E34.5 Androgen insensitivity syndrome
- E34.50 Androgen insensitivity syndrome, unspecified
- E34.51 Complete androgen insensitivity syndrome
- E34.52 Partial androgen insensitivity syndrome
- E34.8 Other specified endocrine disorders
- E34.9 Endocrine disorder, unspecified
Other endocrine disorders (E34)