Hypoparathyroidism (E20)
Clinical Information
Hypoparathyroidism - A condition caused by a deficiency of PARATHYROID HORMONE (or PTH). It is characterized by HYPOCALCEMIA and hyperphosphatemia. Hypocalcemia leads to TETANY. The acquired form is due to removal or injuries to the PARATHYROID GLANDS. The congenital form is due to mutations of genes, such as TBX1; (see DIGEORGE SYNDROME); CASR encoding CALCIUM-SENSING RECEPTOR; or PTH encoding parathyroid hormone.
Pseudohypoparathyroidism - A hereditary syndrome clinically similar to HYPOPARATHYROIDISM. It is characterized by HYPOCALCEMIA; HYPERPHOSPHATEMIA; and associated skeletal development impairment and caused by failure of response to PARATHYROID HORMONE rather than deficiencies. A severe form with resistance to multiple hormones is referred to as Type 1a and is associated with maternal mutant allele of the ALPHA CHAIN OF STIMULATORY G PROTEIN.
Pseudopseudohypoparathyroidism - A form of PSEUDOHYPOPARATHYROIDISM characterized by the same features except for the abnormal response to hormones such as PARATHYROID HORMONE. It is associated with paternally inherited mutant alleles of the ALPHA CHAIN OF STIMULATORY G PROTEIN.
Tetany - A disorder characterized by muscle twitches, cramps, and carpopedal spasm, and when severe, laryngospasm and seizures. This condition is associated with unstable depolarization of axonal membranes, primarily in the peripheral nervous system. Tetany usually results from HYPOCALCEMIA or reduced serum levels of MAGNESIUM that may be associated with HYPERVENTILATION; HYPOPARATHYROIDISM; RICKETS; UREMIA; or other conditions. (From Adams et al., Principles of Neurology, 6th ed, p1490)
Instructional Notations
Type 1 Excludes
A type 1 excludes note is a pure excludes note. It means "NOT CODED HERE!" An Excludes1 note indicates that the code excluded should never be used at the same time as the code above the Excludes1 note. An Excludes1 is used when two conditions cannot occur together, such as a congenital form versus an acquired form of the same condition.
- Di George's syndrome D82.1
- postprocedural hypoparathyroidism E89.2
- tetany NOS R29.0
- transitory neonatal hypoparathyroidism P71.4
Endocrine, nutritional and metabolic diseases (E00–E89)
Disorders of other endocrine glands (E20-E35)
E20 Hypoparathyroidism
- E20.0 Idiopathic hypoparathyroidism
- E20.1 Pseudohypoparathyroidism
E20.8 Other hypoparathyroidism NEW CODE
E20.81 Hypoparathyroidism due to impaired parathyroid hormone secretion NEW CODE
- E20.810 Autosomal dominant hypocalcemia NEW CODE
- E20.811 Secondary hypoparathyroidism in diseases classified elsewhere NEW CODE
- E20.812 Autoimmune hypoparathyroidism NEW CODE
- E20.818 Other specified hypoparathyroidism due to impaired parathyroid hormone secretion NEW CODE
- E20.819 Hypoparathyroidism due to impaired parathyroid hormone secretion, unspecified NEW CODE
- E20.89 Other specified hypoparathyroidism NEW CODE
- E20.9 Hypoparathyroidism, unspecified
Hypoparathyroidism (E20)