2027 ICD-10-CM Diagnosis Code E35Disorders of endocrine glands in diseases classified elsewhere
ICD-10-CM Codes›E00–E89›E20-E35›E35
- Billable — Valid for Submission
- Not Chronic
E35 is a billable ICD-10-CM diagnosis code for disorders of endocrine glands in diseases classified elsewhere. It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027) and groups to MS-DRG 11 through 13, 643 through 645. The code is a manifestation code that cannot be reported as the principal diagnosis. Coders also document this condition as endocrine infection. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Other specified and unspecified endocrine disorders.
Code Identity
Code Classification
Code EditsBilling
Medicare Code Editor checks that affect claim validity for E35.
Approximate SynonymsGuidance
Alternate terms and clinical phrases that map to this code.
- Endocrine infection
Instructional NotesGuidance
Instructions from the official ICD-10-CM Tabular List that apply to E35: its own notes plus those printed at block E20-E35 and Chapter 4. A note printed at a category, block or chapter applies to every code under it.
Excludes1
Not coded here: the excluded code is never reported together with this one, unless the two conditions are unrelated.
- Echinococcus granulosus infection of thyroid gland (B67.3)
- meningococcal hemorrhagic adrenalitis (A39.1)
- syphilis of endocrine gland (A52.79)
- tuberculosis of adrenal gland, except calcification (A18.7)
- tuberculosis of endocrine gland NEC (A18.82)
- tuberculosis of thyroid gland (A18.81)
- Waterhouse-Friderichsen syndrome (A39.1)
Code First
The underlying condition named in the note is sequenced before this code.
- underlying disease, such as:
- late congenital syphilis of thymus gland [Dubois disease] (A50.59)
Notes
General instructions on how these codes are used.
- All neoplasms, whether functionally active or not, are classified in Chapter 2. Appropriate codes in this chapter (i.e. E05.8, E07.0, E16-E31, E34.-) may be used as additional codes to indicate either functional activity by neoplasms and ectopic endocrine tissue or hyperfunction and hypofunction of endocrine glands associated with neoplasms and other conditions classified elsewhere.
Source: CMS ICD-10-CM Tabular List. How to read instructional notes.
Clinical ClassificationClinical
AHRQ’s CCSR groups this code into broader clinical categories.
Patient EducationClinical
Endocrine Diseases
Your endocrine system includes eight major glands throughout your body. These glands make hormones. Hormones are chemical messengers. They travel through your bloodstream to tissues or organs. Hormones work slowly and affect body processes from head to toe. These include:
Read the full article at MedlinePlus
Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.
Convert E35 to ICD-9-CMHistory
The closest ICD-9-CM equivalents under the General Equivalence Mappings.
Code HistoryHistory
Questions About E35Overview
What is the ICD-10 code for disorders of endocrine glands in diseases classified elsewhere?
The ICD-10-CM code for disorders of endocrine glands in diseases classified elsewhere is E35. It is billable on HIPAA-covered claims from October 1, 2026 through September 30, 2027.
Is E35 a billable code?
Yes. This is a billable ICD-10-CM code, specific enough to report disorders of endocrine glands in diseases classified elsewhere on HIPAA-covered claims from October 1, 2026 through September 30, 2027.
What MS-DRG does E35 group to?
On inpatient claims, disorders of endocrine glands in diseases classified elsewhere maps to MS-DRG 12, 644, 645, 11, 13, 643, with relative weights from 0.7461 to 5.6129 depending on complications. Higher weights mean higher Medicare reimbursement.
Can E35 be a principal diagnosis?
No. This is a manifestation code: disorders of endocrine glands in diseases classified elsewhere describes the manifestation of an underlying disease rather than the disease itself, so the underlying condition is sequenced first.
Can E35 be reported with B67.3?
Not as a rule. The Excludes1 note on E35 lists "Echinococcus granulosus infection of thyroid gland (B67.3)". An Excludes1 note means the excluded code is never reported together with this one; the only exception is when the two conditions are unrelated to each other (Official Guidelines, Section I.A.12.a).
