1. Home
  2. ICD-10-CM Codes List
  3. E00–E89
  4. E20-E35
  5. Other disorders of adrenal gland (E27)

Other disorders of adrenal gland (E27)

The ICD-10 code E27 category covers various other disorders of the adrenal gland, including both overactivity and insufficiency conditions not classified elsewhere. These codes are essential for identifying distinct adrenal gland issues such as adrenal hyperfunction, insufficiency, and related crises.

The section includes codes like E27.0 for other adrenocortical overactivity, which encompasses conditions such as premature adrenarche, adrenal virilism, and ACTH hypersecretion without Cushing’s syndrome. E27.1 and E27.4 cover primary and unspecified adrenocortical insufficiency, respectively, including Addison’s disease and familial steroid-resistant nephrotic syndrome with adrenal insufficiency. The E27.2 code identifies the acute and severe form known as Addisonian crisis. Drug-related causes fall under E27.3 for drug-induced insufficiency. Other noteworthy codes are E27.5 for adrenomedullary hyperfunction involving catecholamine excess and E27.8 for other specified disorders like adrenal hyperplasia or inflammation. For conditions that cannot be specifically classified, E27.9 is used. These are critical ICD-10 codes for medical coders diagnosing adrenal gland disorders.

Clinical Terms

The following clinical terms provide additional context, helping users better understand the clinical background and common associations for each diagnosis listed in this section. Including related terms alongside ICD-10-CM codes supports coders, billers, and healthcare professionals in improving accuracy, enhancing documentation, and facilitating research or patient education.

Adrenarche

A stage of development at which the ADRENAL GLANDS undergo maturation leading to the capability of producing increasing amounts of adrenal androgens, DEHYDROEPIANDROSTERONE and ANDROSTENEDIONE. Adrenarche usually begins at about 7 or 8 years of age before the signs of PUBERTY and continues throughout puberty.

Adrenocortical Hyperfunction

Excess production of ADRENAL CORTEX HORMONES such as ALDOSTERONE; HYDROCORTISONE; DEHYDROEPIANDROSTERONE; and/or ANDROSTENEDIONE. Hyperadrenal syndromes include CUSHING SYNDROME; HYPERALDOSTERONISM; and VIRILISM.

Thyroid Hormone Resistance Syndrome

An inherited autosomal recessive trait, characterized by peripheral resistance to THYROID HORMONES and the resulting elevation in serum levels of THYROXINE and TRIIODOTHYRONINE. This syndrome is caused by mutations of gene THRB encoding the THYROID HORMONE RECEPTORS BETA in target cells. HYPOTHYROIDISM in these patients is partly overcome by the increased thyroid hormone levels.