Other disorders of adrenal gland (E27)
The ICD-10 code E27 category covers various other disorders of the adrenal gland, including both overactivity and insufficiency conditions not classified elsewhere. These codes are essential for identifying distinct adrenal gland issues such as adrenal hyperfunction, insufficiency, and related crises.
The section includes codes like E27.0 for other adrenocortical overactivity, which encompasses conditions such as premature adrenarche, adrenal virilism, and ACTH hypersecretion without Cushing’s syndrome. E27.1 and E27.4 cover primary and unspecified adrenocortical insufficiency, respectively, including Addison’s disease and familial steroid-resistant nephrotic syndrome with adrenal insufficiency. The E27.2 code identifies the acute and severe form known as Addisonian crisis. Drug-related causes fall under E27.3 for drug-induced insufficiency. Other noteworthy codes are E27.5 for adrenomedullary hyperfunction involving catecholamine excess and E27.8 for other specified disorders like adrenal hyperplasia or inflammation. For conditions that cannot be specifically classified, E27.9 is used. These are critical ICD-10 codes for medical coders diagnosing adrenal gland disorders.
Endocrine, nutritional and metabolic diseases (E00–E89)
Disorders of other endocrine glands (E20-E35)
E27 Other disorders of adrenal gland
- E27.0 Other adrenocortical overactivity
- E27.1 Primary adrenocortical insufficiency
- E27.2 Addisonian crisis
- E27.3 Drug-induced adrenocortical insufficiency
E27.4 Other and unspecified adrenocortical insufficiency
- E27.40 Unspecified adrenocortical insufficiency
- E27.49 Other adrenocortical insufficiency
- E27.5 Adrenomedullary hyperfunction
- E27.8 Other specified disorders of adrenal gland
- E27.9 Disorder of adrenal gland, unspecified
Other disorders of adrenal gland (E27)
Clinical Terms
The following clinical terms provide additional context, helping users better understand the clinical background and common associations for each diagnosis listed in this section. Including related terms alongside ICD-10-CM codes supports coders, billers, and healthcare professionals in improving accuracy, enhancing documentation, and facilitating research or patient education.
Adrenarche
A stage of development at which the ADRENAL GLANDS undergo maturation leading to the capability of producing increasing amounts of adrenal androgens, DEHYDROEPIANDROSTERONE and ANDROSTENEDIONE. Adrenarche usually begins at about 7 or 8 years of age before the signs of PUBERTY and continues throughout puberty.
Adrenocortical Hyperfunction
Excess production of ADRENAL CORTEX HORMONES such as ALDOSTERONE; HYDROCORTISONE; DEHYDROEPIANDROSTERONE; and/or ANDROSTENEDIONE. Hyperadrenal syndromes include CUSHING SYNDROME; HYPERALDOSTERONISM; and VIRILISM.
Carney Complex
Autosomal dominant syndrome characterized by cardiac and cutaneous MYXOMAS; LENTIGINOSIS (spotty pigmentation of the skin), and endocrinopathy and its associated endocrine tumors. The cardiac myxomas may lead to SUDDEN CARDIAC DEATH and other complications in Carney complex patients. The gene coding for the PRKAR1A protein is one of the causative genetic loci (type 1). A second locus is at chromosome 2p16 (type 2).
