Cushing's syndrome (E24)
The ICD-10 code for Cushing's syndrome is grouped under the category E24, which captures various forms of this hormonal disorder caused by excessive cortisol. These codes help specify the origin and cause, such as pituitary tumors, drug effects, or ectopic hormone production.
This section includes E24.0 for pituitary-dependent Cushing's disease, also known as ACTH-dependent Cushing's syndrome or hypercortisolism due to pituitary adenoma. E24.1 covers Nelson's syndrome, another ACTH-related disorder. E24.2 describes drug-induced or iatrogenic Cushing's syndrome, often from corticosteroid use. E24.3 applies to ectopic ACTH secretion from non-pituitary tumors, while E24.4 identifies alcohol-induced pseudo-Cushing's syndrome. Other variations, including idiopathic or cyclic forms, are classified under E24.8. When the exact cause or type is unclear, E24.9 captures unspecified Cushing's syndrome cases. These distinctions assist healthcare providers and coders in accurately documenting the specific type of Cushing's syndrome encountered in clinical practice.
Instructional Notations
Type 1 Excludes
A type 1 excludes note is a pure excludes note. It means "NOT CODED HERE!" An Excludes1 note indicates that the code excluded should never be used at the same time as the code above the Excludes1 note. An Excludes1 is used when two conditions cannot occur together, such as a congenital form versus an acquired form of the same condition.
- congenital adrenal hyperplasia E25.0
Clinical Terms
The following clinical terms provide additional context, helping users better understand the clinical background and common associations for each diagnosis listed in this section. Including related terms alongside ICD-10-CM codes supports coders, billers, and healthcare professionals in improving accuracy, enhancing documentation, and facilitating research or patient education.
Adrenocortical Hyperfunction
Excess production of ADRENAL CORTEX HORMONES such as ALDOSTERONE; HYDROCORTISONE; DEHYDROEPIANDROSTERONE; and/or ANDROSTENEDIONE. Hyperadrenal syndromes include CUSHING SYNDROME; HYPERALDOSTERONISM; and VIRILISM.
Nelson Syndrome
A syndrome characterized by HYPERPIGMENTATION, enlarging pituitary mass, visual defects secondary to compression of the OPTIC CHIASM, and elevated serum ACTH. It is caused by the expansion of an underlying ACTH-SECRETING PITUITARY ADENOMA that grows in the absence of feedback inhibition by adrenal CORTICOSTEROIDS, usually after ADRENALECTOMY.
