Hypofunction and other disorders of the pituitary gland (E23) ICD-10-CM
The E23 code range covers hypofunction and other disorders of the pituitary gland with 7 ICD-10-CM diagnosis codes. 6 of them are billable and valid for claim submission in fiscal year 2027, and the category headers group them but cannot themselves be billed.
Includes
This note appears immediately under a three character code title to further define, or give examples of, the content of the category.
- the listed conditions whether the disorder is in the pituitary or the hypothalamus
Type 1 Excludes
A type 1 excludes note is a pure excludes note. It means "NOT CODED HERE!" An Excludes1 note indicates that the code excluded should never be used at the same time as the code above the Excludes1 note. An Excludes1 is used when two conditions cannot occur together, such as a congenital form versus an acquired form of the same condition.
Codes in the E23 Range 7 codes · 6 billable
Clinical Terms in This Code Range
Definitions from the National Library of Medicine for conditions coded in the E23 range.
Diabetes Insipidus
A disease that is characterized by frequent urination, excretion of large amounts of dilute URINE, and excessive THIRST. Etiologies of diabetes insipidus include deficiency of antidiuretic hormone (also known as ADH or VASOPRESSIN) secreted by the NEUROHYPOPHYSIS, impaired KIDNEY response to ADH, and impaired hypothalamic regulation of thirst.
Hypopituitarism
Diminution or cessation of secretion of one or more hormones from the anterior pituitary gland (including LH; FOLLICLE STIMULATING HORMONE; SOMATOTROPIN; and CORTICOTROPIN). This may result from surgical or radiation ablation, non-secretory PITUITARY NEOPLASMS, metastatic tumors, infarction, PITUITARY APOPLEXY, infiltrative or granulomatous processes, and other conditions.
Hypothalamic Dysfunction
A finding of an impairment in the normal processes of the hypothalamus.
About the E23 Code Range
These conditions involve reduced pituitary function and other problems affecting the pituitary gland or hypothalamus.
E23.0 identifies hypopituitarism, or reduced pituitary function. E23.1 specifies when a drug causes it. E23.2 identifies diabetes insipidus, while E23.3 identifies hypothalamic dysfunction not classified elsewhere. The remaining subdivisions distinguish other pituitary gland disorders, E23.6, from an unspecified pituitary gland disorder, E23.7.
Questions About This Page
How many billable codes are in the E23 range?
Of the 7 codes in this range, 6 are billable and valid for claim submission from October 1, 2026 through September 30, 2027. Category header codes group them but cannot be reported on claims.
What does the E23 range classify?
The range classifies hypofunction and other disorders of the pituitary gland. Each code links to its own reference page with billing status, MS-DRG grouping, coding notes, and clinical information.
Related References
Source: CMS FY 2027 ICD-10-CM Tabular List and order file, effective October 1, 2026 through September 30, 2027.
