2027 ICD-10-CM Diagnosis Code E88.89Other specified metabolic disorders

Alternate terms and clinical phrases that map to this code.

• Adenosine deaminase overproduction
• Amino acid deficiency
• Angioedema due to disorder of kinin metabolism
• Aromatase excess syndrome
• Arylsulfatase deficiency without MLD
• Autosomal recessive ataxia due to ubiquinone deficiency
• Autosomal recessive distal hereditary motor neuropathy
• Brunner syndrome
• Carnitine deficiency
• Carnitine deficiency due to inborn error of metabolism
• Central nervous system dysfunction in newborn
• Cerebral folate transport deficiency
• Chronic diarrhea due to glucoamylase deficiency
• Chronic diarrhea of infants AND/OR young children
• Chronic infantile diarrhea due to guanylate cyclase 2C overactivity
• Circulating enzyme deficiency
• Clinical manifestation of enzyme deficiency
• Coenzyme Q10 deficiency
• Complete deficiency of methylmalonyl-CoA mutase
• Congenital defect of folate absorption
• COQ7 gene related distal hereditary motor neuropathy
• Corticosteroid 11-reductase deficiency
• CYP2B6 poor metabolizer
• CYP2B6 rapid metabolizer
• CYP2B6 ultra-rapid metabolizer
• CYP2C19 poor metabolizer
• CYP2C19 ultrarapid metabolizer
• CYP2C9 poor metabolizer
• CYP2D6 poor metabolizer
• CYP2D6 ultra-rapid metabolizer
• CYP3A5 poor metabolizer
• Cytochrome p450 CYP1A2 enzyme deficiency
• Cytochrome p450 CYP2E1 enzyme deficiency
• Cytochrome p450 CYP3A enzyme deficiency
• Cytochrome p450 enzyme deficiency
• Cytosolic acetoacetyl-CoA thiolase deficiency
• Decreased metabolic requirement
• Decreased oxygen affinity
• Deficiency of 1,3-beta-glucan synthase
• Deficiency of 1,4-alpha-glucan 6alpha-glucosyltransferase
• Deficiency of 1,4-alpha-glucan branching enzyme
• Deficiency of 2,5-diaminovalerate aminotransferase
• Deficiency of -20-hydroxysteroid dehydrogenase
• Deficiency of -2-hydroxy-acid oxidase
• Deficiency of 3alpha-hydroxycholanate dehydrogenase
• Deficiency of 3-mercaptopyruvate sulfurtransferase
• Deficiency of 3-oxoacid CoA-transferase
• Deficiency of 3-oxoadipate CoA-transferase
• Deficiency of acetate kinase
• Deficiency of acetylcholinesterase
• Deficiency of acetyl-CoA acetyltransferase
• Deficiency of acetylesterase
• Deficiency of acid-ammonia ligase
• Deficiency of aconitate hydratase
• Deficiency of adenosine kinase
• Deficiency of adenosinetriphosphatase
• Deficiency of adenylate kinase
• Deficiency of adenylylsulfate kinase
• Deficiency of ADP deaminase
• Deficiency of alcohol sulfotransferase
• Deficiency of aldehyde dehydrogenase
• Deficiency of aldehyde oxidase
• Deficiency of aldehyde-lyase
• Deficiency of alkaline phosphatase
• Deficiency of alkaline phosphomonoesterase
• Deficiency of alkylhalidase
• Deficiency of alpha- and beta-trypsin
• Deficiency of alpha-1,4-glucan-protein synthase
• Deficiency of alpha-aminoacylpeptide hydrolase
• Deficiency of alpha-ketoglutarate dehydrogenase
• Deficiency of amidase
• Deficiency of amidinotransferase
• Deficiency of amidophosphoribosyltransferase
• Deficiency of amine oxidase
• Deficiency of aryl sulfotransferase
• Deficiency of arylamine acetyltransferase
• Deficiency of arylesterase
• Deficiency of aspartic proteinase
• Deficiency of ATP pyrophosphatase
• Deficiency of azobenzene reductase
• Deficiency of butyrate-acetoacetate CoA-transferase
• Deficiency of butyrylcholinesterase
• Deficiency of carbamate kinase
• Deficiency of carbon-carbon lyase
• Deficiency of carbon-halide lyase
• Deficiency of carbon-nitrogen lyase
• Deficiency of carbon-oxygen lyase
• Deficiency of carbon-sulfur lyase
• Deficiency of carboxylesterase
• Deficiency of carboxylic ester hydrolase
• Deficiency of catechol oxidase
• Deficiency of cathepsin C
• Deficiency of cathepsin D
• Deficiency of cellulase
• Deficiency of chlorophyllase
• Deficiency of choline acetyltransferase
• Deficiency of choline kinase
• Deficiency of choline-phosphate cytidylyltransferase
• Deficiency of cholinephosphotransferase
• Deficiency of chymosin
• Deficiency of chymotrypsin
• Deficiency of chymotrypsin A and B
• Deficiency of citrate-synthase
• Deficiency of creatine kinase
• Deficiency of cytosol non-specific dipeptidase
• Deficiency of D-2-hydroxy-acid dehydrogenase
• Deficiency of dehydrogenase
• Deficiency of dehydrogluconate dehydrogenase
• Deficiency of dehydrogluconokinase
• Deficiency of deoxyribonuclease I
• Deficiency of deoxyribonuclease II
• Deficiency of dephospho-CoA kinase
• Deficiency of dextranase
• Deficiency of dihydroorotase
• Deficiency of diisopropyl-fluorophosphatase
• Deficiency of dimethylallyltranstransferase
• Deficiency of dioxygenase
• Deficiency of dipeptidase
• Deficiency of dipeptide hydrolase
• Deficiency of dipeptidylpeptide hydrolase
• Deficiency of diphosphomevalonate decarboxylase
• Deficiency of diphosphoric monoester hydrolase
• Deficiency of DNA nucleotidylexotransferase
• Deficiency of DNA-directed DNA polymerase
• Deficiency of DNA-directed RNA polymerase
• Deficiency of endopeptidase
• Deficiency of endoribonuclease
• Deficiency of enolase
• Deficiency of enteropeptidase
• Deficiency of epimerase
• Deficiency of erythritol kinase
• Deficiency of estradiol 6beta-monooxygenase
• Deficiency of ethanolamine-phosphate cytidylyltransferase
• Deficiency of ethanolaminephosphotransferase
• Deficiency of ether hydrolase
• Deficiency of exoribonuclease
• Deficiency of FMN adenylyltransferase
• Deficiency of formaldehyde dehydrogenase
• Deficiency of formamidase
• Deficiency of formate dehydrogenase
• Deficiency of formate-tetrahydrofolate ligase
• Deficiency of formiminotetrahydrofolate cyclodeaminase
• Deficiency of formyltetrahydrofolate deformylase
• Deficiency of fumarylacetoacetase
• Deficiency of galactonolactone dehydrogenase
• Deficiency of glucosamine acetyltransferase
• Deficiency of glucosamine kinase
• Deficiency of glucosamine-phosphate acetyltransferase
• Deficiency of glutathione reductase
• Deficiency of glycerate kinase
• Deficiency of glycerol-3-phosphate acyltransferase
• Deficiency of glycerophosphatase
• Deficiency of glycogen synthase a kinase
• Deficiency of guanine deaminase
• Deficiency of guanylate cyclase 2C
• Deficiency of heparin lyase
• Deficiency of hexose oxidase
• Deficiency of hexosyltransferase
• Deficiency of histidinol dehydrogenase
• Deficiency of hyaluronate lyase
• Deficiency of hyaluronoglucosaminidase
• Deficiency of hydrogen-sulfide acetyltransferase
• Deficiency of hydrolase
• Deficiency of hydrolyase
• Deficiency of hydroxyacylglutathione hydrolase
• Deficiency of hydroxyalkyl-protein kinase
• Deficiency of hydroxymethylglutaryl-CoA hydrolase
• Deficiency of hydroxymethylglutaryl-CoA reductase
• Deficiency of hydroxymethylglutaryl-CoA synthase
• Deficiency of IMP cyclohydrolase
• Deficiency of IMP dehydrogenase
• Deficiency of inorganic pyrophosphatase
• Deficiency of isobutyryl-CoA dehydrogenase
• Deficiency of isocitrate lyase
• Deficiency of isomerase
• Deficiency of isopentenyl-diphosphate delta-isomerase
• Deficiency of ketotetrose-phosphate aldolase
• Deficiency of lactonase
• Deficiency of lactoylglutathione lyase
• Deficiency of L-arabinose dehydrogenase
• Deficiency of leucine aminopeptidase
• Deficiency of leukotriene C4 synthase
• Deficiency of L-gulonate dehydrogenase
• Deficiency of lichenase
• Deficiency of ligase
• Deficiency of limit dextrinase
• Deficiency of lyase
• Deficiency of lysine-tRNA ligase
• Deficiency of lysolecithin acylmutase
• Deficiency of lysophospholipase
• Deficiency of lysostaphin
• Deficiency of lysozyme
• Deficiency of malate dehydrogenase
• Deficiency of mannitol dehydrogenase
• Deficiency of mannose-6-phosphate isomerase
• Deficiency of metallocarboxypeptidase
• Deficiency of metalloproteinase
• Deficiency of methenyltetrahydrofolate cyclohydrolase
• Deficiency of methylaspartate mutase
• Deficiency of methylenetetrahydrofolate dehydrogenase
• Deficiency of methylglutaconyl-CoA hydratase
• Deficiency of methylmalonyl-CoA mutase
• Deficiency of methylmalonyl-coenzyme A epimerase
• Deficiency of methyltransferase
• Deficiency of mevaldate reductase
• Deficiency of mevalonate kinase
• Deficiency of monoamine oxidase
• Deficiency of monodehydroascorbate reductase
• Deficiency of monooxygenase
• Deficiency of mutase
• Deficiency of myo-inositol oxygenase
• Deficiency of N-acetyl-beta-glucosaminidase
• Deficiency of N-acetylneuraminate lyase
• Deficiency of NAD
• Deficiency of NAD^+^ kinase
• Deficiency of NAD^+^ nucleosidase
• Deficiency of NAD^+^ synthase
• Deficiency of NAD^+^ transhydrogenase
• Deficiency of NADase
• Deficiency of NADH dehydrogenase
• Deficiency of nicotinamide methyltransferase
• Deficiency of nicotinamide phosphoribosyltransferase
• Deficiency of nicotinamide-nucleotide adenylyltransferase
• Deficiency of nicotinate dehydrogenase
• Deficiency of nicotinate phosphoribosyltransferase
• Deficiency of nucleosidase
• Deficiency of nucleoside-diphosphatase
• Deficiency of nucleoside-diphosphate kinase
• Deficiency of nucleoside-phosphate kinase
• Deficiency of nucleotidase
• Deficiency of nucleotide pyrophosphatase
• Deficiency of nucleotidyltransferase
• Deficiency of omega peptidase
• Deficiency of orotate phosphoribosyltransferase
• Deficiency of oxalate CoA-transferase
• Deficiency of oxidase
• Deficiency of oximinotransferase
• Deficiency of oxo-acid-lyase
• Deficiency of oxoglutarate dehydrogenase
• Deficiency of oxygenase
• Deficiency of pancreatic elastase
• Deficiency of pantetheine kinase
• Deficiency of pantetheine-phosphate adenylyltransferase
• Deficiency of pantothenoylcysteine decarboxylase
• Deficiency of pentosyltransferase
• Deficiency of pepsin A
• Deficiency of pepsin B
• Deficiency of peptide hydrolase
• Deficiency of peroxidase
• Deficiency of phenylalanine 4-monooxygenase
• Deficiency of phenylpyruvate tautomerase
• Deficiency of phosphatase
• Deficiency of phosphatidate phosphatase
• Deficiency of phosphoacetylglucosamine mutase
• Deficiency of phosphoadenylate 3'-nucleotidase
• Deficiency of phosphoamidase
• Deficiency of phosphoglucomutase
• Deficiency of phosphogluconate dehydrogenase
• Deficiency of phosphoglycerate mutase
• Deficiency of phosphoketolase
• Deficiency of phospholipase A>2<
• Deficiency of phospholipase C
• Deficiency of phospholipase D
• Deficiency of phosphomevalonate kinase
• Deficiency of phosphopantothenate-cysteine ligase
• Deficiency of phosphoprotein phosphatase
• Deficiency of phosphoribokinase
• Deficiency of phosphoribosylamine-glycine ligase
• Deficiency of phosphoribosylglycinamide formyltransferase
• Deficiency of phosphoric diester hydrolase
• Deficiency of phosphoric monoester hydrolase
• Deficiency of phosphorus-oxygen lyase
• Deficiency of phosphorylase kinase
• Deficiency of phosphorylase phosphatase
• Deficiency of phosphotransferase
• Deficiency of plasmin
• Deficiency of polygalacturonase
• Deficiency of polyribonucleotide nucleotidyltransferase
• Deficiency of progesterone 11alpha-monooxygenase
• Deficiency of protease
• Deficiency of protein kinase
• Deficiency of protocatechuate 3,4-dioxygenase
• Deficiency of pyridoxal kinase
• Deficiency of pyridoxamine-phosphate oxidase
• Deficiency of pyrophosphotransferase
• Deficiency of pyrroline-2-carboxylate reductase
• Deficiency of pyruvate kinase
• Deficiency of racemase
• Deficiency of reductase
• Deficiency of renin
• Deficiency of retinal isomerase
• Deficiency of riboflavin kinase
• Deficiency of ribokinase
• Deficiency of ribonuclease
• Deficiency of ribose-5-phosphate isomerase
• Deficiency of ribose-phosphate pyrophosphokinase
• Deficiency of ribosomal cathepsin
• Deficiency of ribosomal neutral proteinase
• Deficiency of ribosylnicotinamide kinase
• Deficiency of ribulokinase
• Deficiency of ribulose-phosphate 3-epimerase
• Deficiency of sarcoplasmic reticulum calcium-ATPase 1
• Deficiency of sedoheptulokinase
• Deficiency of serine proteinase
• Deficiency of shikimate dehydrogenase
• Deficiency of sialidase
• Deficiency of squalene monooxygenase
• Deficiency of steroid 17-alpha-monooxygenase
• Deficiency of steroid delta-isomerase
• Deficiency of succinate dehydrogenase
• Deficiency of succinate-CoA ligase
• Deficiency of succinyl-CoA hydrolase
• Deficiency of sulfate adenylyltransferase
• Deficiency of sulfinoalanine decarboxylase
• Deficiency of sulfite reductase
• Deficiency of sulfotransferase
• Deficiency of sulfuric ester hydrolase
• Deficiency of sulfurtransferase
• Deficiency of tannase
• Deficiency of thiamine pyridinylase
• Deficiency of thiamine pyrophosphokinase
• Deficiency of thioethanolamine acetyltransferase
• Deficiency of thioether hydrolase
• Deficiency of thiolester hydrolase
• Deficiency of thiosulfate sulfurtransferase
• Deficiency of thrombin
• Deficiency of transacylase
• Deficiency of transaldolase
• Deficiency of transcarbamoylase
• Deficiency of transcarboxylase
• Deficiency of transferase
• Deficiency of transformiminase
• Deficiency of transformylase
• Deficiency of transketolase
• Deficiency of triacylglycerol lipase
• Deficiency of tripeptide aminopeptidase
• Deficiency of triphosphoric monoester hydrolase
• Deficiency of tropinesterase
• Deficiency of trypsin
• Deficiency of tyrosine aminotransferase
• Deficiency of UDPglucose dehydrogenase
• Deficiency of unspecific monooxygenase
• Deficiency of uracil dehydrogenase
• Deficiency of uracil phosphoribosyltransferase
• Deficiency of uronolactonase
• Deficiency of UTP-glucose-1-phosphate uridylyltransferase
• Deficiency of UTP-hexose-1-phosphate uridylyltransferase
• Deficiency of w-amidase
• Deficiency of Xaa-Pro dipeptidase
• Deficiency of xylan endo-1,3-beta-xylosidase
• Deficiency of Zeta-chain associated protein kinase 70
• Diffuse organ or tissue uptake
• Dilated cardiomyopathy due to familial storage disease
• Dilated cardiomyopathy due to lysosomal storage disease
• Dilated cardiomyopathy due to metabolic disorder
• Disorder due to N-acetyltransferase enzyme variant
• Disorder of beta and omega amino acid metabolism
• Disorder of blood gas
• Disorder of cortisol-cortisone shuttle
• Disorder of gamma aminobutyric acid metabolism
• Disorder of iodine metabolism
• Disorder of lysosomal enzyme
• Disorder of organic acid metabolism
• Disorder of oxygen transport
• Disorder of propionate AND/OR methylmalonate metabolism
• Disorder of protein metabolism
• Disorder of sialic acid metabolism
• Disorder of steroid metabolism
• DPYD poor metabolizer
• Epsilon-N-trimethyllysine hydroxylase carnitine deficiency disorder
• Erythrocyte enzyme deficiency
• Ethanolaminosis
• Etiocholanolone fever
• Folic acid deficiency
• Folinic acid responsive developmental and epileptic encephalopathy
• Fumarate hydratase deficiency
• Fumarylacetoacetase deficiency, acute type
• Glucose phosphate isomerase deficiency
• Glutathione S-transferase deficiency
• Hyperimidodipeptiduria
• Hypermetabolism
• Hypermethioninemia
• Hyperthermia-hyperphagia-hypothyroidism syndrome
• Hypertrophic cardiomyopathy due to lysosomal disease
• Impaired oxygen delivery
• Impaired oxygen extraction
• Increased auto-oxidation
• Increased metabolic requirement
• Increased oxygen affinity
• Increased oxygen demand
• Inherited disorder of folate metabolism
• Intestinal enteropeptidase deficiency
• Intestinal obstruction in newborn due to guanylate cyclase 2C deficiency
• Ketoacidosis due to monocarboxylate transporter-1 deficiency
• Ketonemia
• Ketosis
• Ketotic hypoglycemia
• Liposynovitis prepatellaris
• Lipoyl transferase 2 deficiency
• Meconium ileus
• Metabolic disorder of transport
• Metabolic myopathy due to lactate transporter defect
• Methylcrotonic aciduria
• Methylmalonate semialdehyde dehydrogenase deficiency
• Mevalonic aciduria
• Mitochondrial 2-methylacetoacetyl-CoA thiolase deficiency - non-potassium stimulated
• Mucolipidosis
• Muscle D-lactate dehydrogenase deficiency
• NADHX dehydratase deficiency
• NADHX epimerase deficiency
• Neonatal obstruction of intestine
• Non-amino organic acidemia AND/OR aciduria
• NUDT15 intermediate metabolizer
• NUDT15 poor metabolizer
• NUDT15 possible intermediate metabolizer
• Pancreatic colipase deficiency
• Pancreatic malabsorption
• Partial deficiency of methylmalonyl-CoA mutase
• Patchy organ or tissue uptake
• Pentose disorder
• Perinatal intestinal obstruction
• Prepatellar bursitis
• Progressive polyneuropathy with bilateral striatal necrosis
• Progressive retinal dystrophy due to retinol transport defect
• Proteinosis
• Pseudohypoaldosteronism
• Pseudohypoaldosteronism type 2A
• Pseudohypoaldosteronism, type 1
• Pseudohypoaldosteronism, type 1, dominant form
• Pseudohypoaldosteronism, type 1, recessive form
• Pseudohypoaldosteronism, type 2
• Psychomotor retardation due to S-adenosylhomocysteine hydrolase deficiency
• Pyridoxine-dependent developmental and epileptic encephalopathy
• Rowley-Rosenberg syndrome
• S-adenosylhomocysteine hydrolase deficiency
• Secondary carnitine deficiency
• Short stature, developmental delay, congenital heart defect syndrome
• Sialic acid storage disease, severe infantile type
• Sialic storage disease
• Sialuria
• SLCO1B1 decreased function
• SLCO1B1 poor function
• Specific enzyme deficiency
• Steatosis
• Steroid dehydrogenase deficiency and dental anomaly syndrome
• Testosterone 17-beta-dehydrogenase deficiency
• TPMT poor metabolizer
• Transient pseudohypoaldosteronism
• Trypsinogen deficiency
• UGT1A1 poor metabolizer

Instructions from the official ICD-10-CM Tabular List that apply to E88.89: its own notes plus those printed at E88, block E70-E88, and Chapter 4. A note printed at a category, block or chapter applies to every code under it.

Source: CMS ICD-10-CM Tabular List. How to read instructional notes.

Alphabetical index entries that point to this code.

• Adenolipomatosis, Launois-Bensaude E88.89

• Deficiency, deficient

  • dihydropyrimidine dehydrogenase (DPD) E88.89

• Dihydropyrimidine dehydrogenase disease (DPD) E88.89

• Disease, diseased See Also: Syndrome;

  • Erdheim-Chester (ECD) E88.89

• Disorder (of) See Also: Disease;

  • metabolism NOS E88.9

    • specified NEC E88.89

• DPD (dihydropyrimidine dehydrogenase deficiency) E88.89

• Hoffa-Kastert disease E88.89

• Hoffa's disease E88.89

• Ketosis NEC E88.89

• Launois-Bensaude adenolipomatosis E88.89

• Lipomatosis E88.2

  • Launois-Bensaude E88.89

• Liposynovitis prepatellaris E88.89

• Madelung's

  • disease

    • symmetrical lipomas, neck E88.89

• Steatosis E88.89

• Syndrome See Also: Disease;

  • Erdheim-Chester (ECD) E88.89