2027 ICD-10-CM Diagnosis Code E34.8Other specified endocrine disorders
ICD-10-CM Codes›E00–E89›E20-E35›E34
- Billable — Valid for Submission
- Not Chronic
E34.8 is a billable ICD-10-CM diagnosis code for other specified endocrine disorders. It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027) and groups to MS-DRG 643 through 645. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Other specified and unspecified endocrine disorders.
Code Identity
Code Classification
Approximate SynonymsGuidance
Alternate terms and clinical phrases that map to this code.
- Abnormal corticosterone
- Abnormal estradiol
- Abnormal serotonin
- Abnormality of serotonin secretion
- Acrogeria
- Acroosteolysis
- Acroosteolysis, keloid-like lesions, premature aging syndrome
- Aging
- Atypical Werner syndrome
- Autoimmune endocrine disease
- Calcification of pineal gland
- Complex gonadal endocrine disorder
- Congenital anomaly of subcutaneous tissue
- Diabetes mellitus due to genetic defect in insulin action
- Disorder of androgen receptor
- Disorder of endocrine gonad
- Endocrine alopecia
- Endocrine andrology disorder
- Endocrine axis dysfunction
- Euthyroid Graves orbitopathy
- General adaptation syndrome
- Gynecological endocrinology disorder
- Hereditary acroosteolysis
- Hutchinson-Gilford syndrome
- Hypothalamic-pituitary-adrenal axis dysfunction
- Hypothalamic-pituitary-gonadal axis dysfunction
- Hypothalamic-pituitary-ovarian axis dysfunction
- Hypothalamic-pituitary-testicular axis dysfunction
- Insulin biosynthesis defect
- Insulin receptor defect
- Insulin resistance
- Laminopathy with premature aging
- Leprechaunism syndrome
- LMNA-related cardiocutaneous progeria syndrome
- Macrogenitosomia
- Macrogenitosomia praecox due to pineal disorder
- MADD-related developmental delay, endocrine dysfunction, hypohemoglobinemia syndrome
- Malabsorption of glucose
- Mandibular hypoplasia, deafness, progeroid syndrome
- Mandibuloacral dysplasia associated to MTX2
- Marfan's syndrome
- Mass of endocrine structure
- Metageria
- Multiple malformation syndrome with senile-like appearance
- Neonatal pseudo-hydrocephalic progeroid syndrome
- Nestor Guillermo progeria syndrome
- Pineal degeneration
- Pineal gland disorder
- Pineal gland dysfunction
- Premature aging
- Premature aging syndrome
- Progeroid and marfanoid aspect, lipodystrophy syndrome
- Progeroid features, hepatocellular carcinoma predisposition syndrome
- Progeroid short stature with pigmented nevi
- Progeroid syndrome Petty type
- Rabson-Mendenhall syndrome
- Retinitis pigmentosa, hearing loss, premature aging, short stature, facial dysmorphism syndrome
- Structural abnormality of pineal gland
- Werner syndrome
- Wormian bone of cranium
- Wormian bones, micrognathia, abnormal dentition, progeroid syndrome
Instructional NotesGuidance
Instructions from the official ICD-10-CM Tabular List that apply to E34.8: its own notes plus those printed at E34, block E20-E35, and Chapter 4. A note printed at a category, block or chapter applies to every code under it.
Applicable To
Conditions this code is used for: synonyms of the title or, for "other specified" codes, the conditions assigned to it. The list is not exhaustive.
- Pineal gland dysfunction
- Progeria
Excludes1
Not coded here: the excluded code is never reported together with this one, unless the two conditions are unrelated.
Excludes2
Not included here: the excluded condition is not part of this code, but a patient may have both, so both codes may be reported.
- pseudohypoparathyroidism (E20.1)
Notes
General instructions on how these codes are used.
- All neoplasms, whether functionally active or not, are classified in Chapter 2. Appropriate codes in this chapter (i.e. E05.8, E07.0, E16-E31, E34.-) may be used as additional codes to indicate either functional activity by neoplasms and ectopic endocrine tissue or hyperfunction and hypofunction of endocrine glands associated with neoplasms and other conditions classified elsewhere.
Source: CMS ICD-10-CM Tabular List. How to read instructional notes.
Referenced in Other NotesGuidance
Instructional notes printed at other codes that name E34.8, its category, or a range that includes it.
Excludes1 3
These codes carry an Excludes1 note naming E34.8: they are not reported together with it, unless the two conditions are unrelated.
Code First 1
These codes say to code first a condition named in the note, and E34.8 is one of the conditions named.
- G63 Polyneuropathy in diseases classified elsewhere
Notes 1
These notes mention E34.8.
- Chapter 4 (E00-E89) Endocrine, nutritional and metabolic diseasesAll neoplasms, whether functionally active or not, are classified in Chapter 2. Appropriate codes in this chapter (i.e. E05.8, E07.0, E16-E31, E34.-) may be used as additional codes to indicate either functional activity by neoplasms and ectopic endocrine tissue or hyperfunction and hypofunction of endocrine glands associated with neoplasms and other conditions classified elsewhere. names E34.-, which includes this code
Index to Diseases and InjuriesGuidance
Alphabetical index entries that point to this code.
pineal gland E34.8
Disease, diseased See Also: Syndrome;
pineal gland E34.8
Donohue's syndrome E34.8
pineal gland E34.8
Hyperpinealism E34.8
Hypopinealism E34.8
Leprechaunism E34.8
Pellizzi's syndrome E34.8
Presenile See Also: condition;
premature aging E34.8
Progeria E34.8
Senile, senility See Also: condition; R41.81
premature E34.8
Syndrome See Also: Disease;
pineal E34.8
premature senility E34.8
Werner's E34.8
Clinical ClassificationClinical
AHRQ’s CCSR groups this code into broader clinical categories.
Clinical InformationClinical
Donohue Syndrome
rare autosomal recessive syndrome of extreme insulin resistance due to mutations in the binding domain of insulin receptor. clinical features include severe intrauterine and postnatal growth restriction, characteristic dysmorphic facies; hirsutism; virilization; multiple endocrine abnormalities, and early death.Progeria
an abnormal congenital condition, associated with defects in the lamin type a gene, which is characterized by premature aging in children, where all the changes of cell senescence occur. it is manifested by premature graying; hair loss; hearing loss (deafness); cataracts (cataract); arthritis; osteoporosis; diabetes mellitus; atrophy of subcutaneous fat; skeletal hypoplasia; elevated urinary hyaluronic acid; and accelerated atherosclerosis. many affected individuals develop malignant tumors, especially sarcoma.
Patient EducationClinical
Endocrine Diseases
Your endocrine system includes eight major glands throughout your body. These glands make hormones. Hormones are chemical messengers. They travel through your bloodstream to tissues or organs. Hormones work slowly and affect body processes from head to toe. These include:
Read the full article at MedlinePlus
Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.
Convert E34.8 to ICD-9-CMHistory
The closest ICD-9-CM equivalents under the General Equivalence Mappings.
Code HistoryHistory
Questions About E34.8Overview
What is the ICD-10 code for other specified endocrine disorders?
The ICD-10-CM code for other specified endocrine disorders is E34.8 (sometimes written as E348). It is billable on HIPAA-covered claims from October 1, 2026 through September 30, 2027.
Is E34.8 (Other endocrine disorders) a billable code?
Yes. This is a billable ICD-10-CM code, specific enough to report other specified endocrine disorders on HIPAA-covered claims from October 1, 2026 through September 30, 2027.
What MS-DRG does E34.8 group to?
When other specified endocrine disorders is the principal diagnosis on an inpatient stay, it groups to MS-DRG 644, 645, 643, with relative weights from 0.7461 to 1.6138 depending on complications. Higher weights mean higher Medicare reimbursement.
Can E34.8 be reported with E20.1?
Not as a rule. The Excludes1 note at E34, which applies to E34.8, lists "pseudohypoparathyroidism (E20.1)". An Excludes1 note means the excluded code is never reported together with this one; the only exception is when the two conditions are unrelated to each other (Official Guidelines, Section I.A.12.a).
What is the ICD-9 equivalent of E34.8?
Under the General Equivalence Mappings, other specified endocrine disorders converts to ICD-9-CM 259.8 (endocrine disorders NEC). The mapping is approximate, so confirm the match fits the documentation.
