2027 ICD-10-CM Diagnosis Code E30.1Precocious puberty

ICD-10-CM Codes›E00–E89›E20-E35›E30

ICD-10-CM E30.1
CMSSource: CMS FY 2027 ICD-10-CM dataset · Effective Oct 1, 2026 – Sep 30, 2027

E30.1 is a billable ICD-10-CM diagnosis code for precocious puberty. It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027) and groups to MS-DRG 643 through 645. The code is restricted by the Medicare Code Editor to pediatric patients (age 0 through 17). In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Other specified and unspecified endocrine disorders.

Code Identity

ICD-10-CM Code
E30.1
Billable Status
Yes — Valid for Submission
Code Describes
Precocious puberty
Short Description
Precocious puberty
Same as the full description in the CMS dataset.
Parent Code
Disorders of puberty, not elsewhere classified

Code Classification

ChapterE00–E89Endocrine, nutritional and metabolic diseases
SectionE20-E35Disorders of other endocrine glands
CategoryE30Disorders of puberty, not elsewhere classified
This CodeE30.1Precocious puberty

Code EditsBilling

Medicare Code Editor checks that affect claim validity for E30.1.

The Medicare Code Editor detects inconsistencies in pediatric cases by checking a patient's age and any diagnosis on the patient's record. The pediatric code edits apply to patients age range is 0–17 years inclusive (e.g., Reye's syndrome, routine child health exam).

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Adrenal hyperfunction
  • Adrenocortical hyperfunction
  • Congenital anomaly of endocrine testis
  • Cryptogenic sexual precocity
  • Early menarche
  • Endocrine disorder related to puberty
  • Familial male-limited precocious puberty
  • Female puberty disorder
  • Finding of secondary sexual hair growth
  • Gonadotropin independent precocious puberty
  • Heterosexual precocious puberty
  • Isosexual precocious puberty
  • Menarche
  • Peripheral precocious puberty due to hyperestrogenism
  • Physical precocity
  • Precocious female puberty
  • Precocious pubarche
  • Precocious puberty
  • Precocious puberty due to adrenal hyperplasia
  • Precocious puberty due to adrenocortical hyperfunction
  • Premature growth of secondary sexual hair
  • Spastic paraplegia with precocious puberty syndrome

Instructional NotesGuidance

Instructions from the official ICD-10-CM Tabular List that apply to E30.1: its own notes plus those printed at block E20-E35 and Chapter 4. A note printed at a category, block or chapter applies to every code under it.

Applicable To

Conditions this code is used for: synonyms of the title or, for "other specified" codes, the conditions assigned to it. The list is not exhaustive.

  • Precocious menstruation

Excludes1

Not coded here: the excluded code is never reported together with this one, unless the two conditions are unrelated.

On E30.1 itself
  • Albright (-McCune) (-Sternberg) syndrome (Q78.1)
  • central precocious puberty (E22.8)
  • congenital adrenal hyperplasia (E25.0)
  • female heterosexual precocious pseudopuberty (E25.-)
  • male isosexual precocious pseudopuberty (E25.-)
From Block E20-E35 Disorders of other endocrine glands applies to 99 codes
From Chapter 4 (E00-E89) Endocrine, nutritional and metabolic diseases applies to 973 codes
  • transitory endocrine and metabolic disorders specific to newborn (P70-P74)

Notes

General instructions on how these codes are used.

From Chapter 4 (E00-E89) Endocrine, nutritional and metabolic diseases applies to 973 codes
  • All neoplasms, whether functionally active or not, are classified in Chapter 2. Appropriate codes in this chapter (i.e. E05.8, E07.0, E16-E31, E34.-) may be used as additional codes to indicate either functional activity by neoplasms and ectopic endocrine tissue or hyperfunction and hypofunction of endocrine glands associated with neoplasms and other conditions classified elsewhere.

Source: CMS ICD-10-CM Tabular List. How to read instructional notes.

Referenced in Other NotesGuidance

Instructional notes printed at other codes that name E30.1, its category, or a range that includes it.

Excludes1 2

These codes carry an Excludes1 note naming E30.1: they are not reported together with it, unless the two conditions are unrelated.

  • N92 Excessive, frequent and irregular menstruation
    precocious puberty (menstruation) (E30.1)
  • N93 Other abnormal uterine and vaginal bleeding
    precocious puberty (menstruation) (E30.1)

Code First 1

These codes say to code first a condition named in the note, and E30.1 is one of the conditions named.

  • G63 Polyneuropathy in diseases classified elsewhere
    endocrine disease, except diabetes (E00-E07, E15-E16, E20-E34) names E20-E34, which includes this code

Notes 1

These notes mention E30.1.

  • Chapter 4 (E00-E89) Endocrine, nutritional and metabolic diseases
    All neoplasms, whether functionally active or not, are classified in Chapter 2. Appropriate codes in this chapter (i.e. E05.8, E07.0, E16-E31, E34.-) may be used as additional codes to indicate either functional activity by neoplasms and ectopic endocrine tissue or hyperfunction and hypofunction of endocrine glands associated with neoplasms and other conditions classified elsewhere. names E16-E31, which includes this code

Index to Diseases and InjuriesGuidance

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR END015
Other specified and unspecified endocrine disorders
Default principal diagnosis: inpatient Yes · outpatient Yes

Clinical InformationClinical

  • Puberty, Precocious

    development of sexual maturation in boys and girls at a chronological age that is 2.5 standard deviations below the mean age at onset of puberty in the population. this early maturation of the hypothalamic-pituitary-gonadal axis results in sexual precocity, elevated serum levels of gonadotropins and gonadal steroid hormones such as estradiol and testosterone.

Patient EducationClinical

Puberty

Puberty is the time in life when a boy or girl becomes sexually mature. It is a process that usually happens between ages 8 and 13 for girls and ages 9 and 14 for boys. It causes physical changes and affects boys and girls differently.

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert E30.1 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
259.1 Sexual precocity NEC
Approximate The match is approximate rather than exact.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2026No changes
FY 2027CurrentCurrent code set, no changesEffective October 1, 2026 through September 30, 2027.

Questions About E30.1Overview

What is the ICD-10 code for precocious puberty?

The ICD-10-CM code for precocious puberty is E30.1 (sometimes written as E301). It is billable on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

Is E30.1 (Disorders of puberty, not elsewhere classified) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report precocious puberty on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

What MS-DRG does E30.1 group to?

When precocious puberty is the principal diagnosis on an inpatient stay, it groups to MS-DRG 644, 645, 643, with relative weights from 0.7461 to 1.6138 depending on complications. Higher weights mean higher Medicare reimbursement.

Who can E30.1 be reported for?

The Medicare Code Editor checks precocious puberty against patient demographics: this code is intended for pediatric patients (age 0 through 17). Claims outside these limits are flagged as inconsistent.

Can E30.1 be reported with Q78.1?

Not as a rule. The Excludes1 note on E30.1 lists "Albright (-McCune) (-Sternberg) syndrome (Q78.1)". An Excludes1 note means the excluded code is never reported together with this one; the only exception is when the two conditions are unrelated to each other (Official Guidelines, Section I.A.12.a).