ICD-10-CM Code E31.22

Multiple endocrine neoplasia [MEN] type IIA

Version 2021 Billable Code

Valid for Submission

E31.22 is a billable code used to specify a medical diagnosis of multiple endocrine neoplasia [men] type iia. The code is valid for the fiscal year 2021 for the submission of HIPAA-covered transactions. The ICD-10-CM code E31.22 might also be used to specify conditions or terms like benign multiple endocrine neoplasia type 2a, malignant multiple endocrine neoplasia type 2a, multiple endocrine neoplasia type 2a, multiple endocrine neoplasia, type 2, neoplasm of uncertain behavior of multiple endocrine glands, polyglandular activity in multiple endocrine adenomatosis, etc

ICD-10:E31.22
Short Description:Multiple endocrine neoplasia [MEN] type IIA
Long Description:Multiple endocrine neoplasia [MEN] type IIA

Tabular List of Diseases and Injuries

The Tabular List of Diseases and Injuries is a list of ICD-10 codes, organized "head to toe" into chapters and sections with guidance for inclusions, exclusions, descriptions and more. The following references are applicable to the code E31.22:

Inclusion Terms

Inclusion Terms
These terms are the conditions for which that code is to be used. The terms may be synonyms of the code title, or, in the case of "other specified" codes, the terms are a list of the various conditions assigned to that code. The inclusion terms are not necessarily exhaustive. Additional terms found only in the Alphabetic Index may also be assigned to a code.
  • Sipple's syndrome

Index to Diseases and Injuries

The Index to Diseases and Injuries is an alphabetical listing of medical terms, with each term mapped to one or more ICD-10 code(s). The following references for the code E31.22 are found in the index:


Synonyms

The following clinical terms are approximate synonyms or lay terms that might be used to identify the correct diagnosis code:

  • Benign multiple endocrine neoplasia type 2a
  • Malignant multiple endocrine neoplasia type 2a
  • Multiple endocrine neoplasia type 2A
  • Multiple endocrine neoplasia, type 2
  • Neoplasm of uncertain behavior of multiple endocrine glands
  • Polyglandular activity in multiple endocrine adenomatosis

Diagnostic Related Groups

The ICD-10 code E31.22 is grouped in the following groups for version MS-DRG V38.0 What are Diagnostic Related Groups?
The Diagnostic Related Groups (DRGs) are a patient classification scheme which provides a means of relating the type of patients a hospital treats. The DRGs divides all possible principal diagnoses into mutually exclusive principal diagnosis areas referred to as Major Diagnostic Categories (MDC).
applicable from 10/01/2020 through 09/30/2021.

  • 643 - ENDOCRINE DISORDERS WITH MCC
  • 644 - ENDOCRINE DISORDERS WITH CC
  • 645 - ENDOCRINE DISORDERS WITHOUT CC/MCC

Convert E31.22 to ICD-9

  • 258.02 - Mult endo neop type IIA

Code Classification

  • Endocrine, nutritional and metabolic diseases (E00–E90)
    • Disorders of other endocrine glands (E20-E35)
      • Polyglandular dysfunction (E31)

Code History

  • FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016
    (First year ICD-10-CM implemented into the HIPAA code set)
  • FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
  • FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
  • FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
  • FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020
  • FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021

Information for Patients


Endocrine Diseases

Your endocrine system includes eight major glands throughout your body. These glands make hormones. Hormones are chemical messengers. They travel through your bloodstream to tissues or organs. Hormones work slowly and affect body processes from head to toe. These include

  • Growth and development
  • Metabolism - digestion, elimination, breathing, blood circulation and maintaining body temperature
  • Sexual function
  • Reproduction
  • Mood

If your hormone levels are too high or too low, you may have a hormone disorder. Hormone diseases also occur if your body does not respond to hormones the way it is supposed to. Stress, infection and changes in your blood's fluid and electrolyte balance can also influence hormone levels.

In the United States, the most common endocrine disease is diabetes. There are many others. They are usually treated by controlling how much hormone your body makes. Hormone supplements can help if the problem is too little of a hormone.

  • Androgen insensitivity syndrome (Medical Encyclopedia)
  • Endocrine glands (Medical Encyclopedia)
  • Hypogonadotropic hypogonadism (Medical Encyclopedia)
  • Intersex (Medical Encyclopedia)
  • Multiple endocrine neoplasia (MEN) I (Medical Encyclopedia)
  • Multiple endocrine neoplasia (MEN) II (Medical Encyclopedia)
  • Zollinger-Ellison syndrome (Medical Encyclopedia)

[Learn More]

Multiple endocrine neoplasia Multiple endocrine neoplasia is a group of disorders that affect the body's network of hormone-producing glands called the endocrine system. Hormones are chemical messengers that travel through the bloodstream and regulate the function of cells and tissues throughout the body. Multiple endocrine neoplasia typically involves tumors (neoplasia) in at least two endocrine glands; tumors can also develop in other organs and tissues. These growths can be noncancerous (benign) or cancerous (malignant). If the tumors become cancerous, the condition can be life-threatening.The major forms of multiple endocrine neoplasia are called type 1, type 2, and type 4. These types are distinguished by the genes involved, the types of hormones made, and the characteristic signs and symptoms.Many different types of tumors are associated with multiple endocrine neoplasia. Type 1 frequently involves tumors of the parathyroid glands, the pituitary gland, and the pancreas. Tumors in these glands can lead to the overproduction of hormones. The most common sign of multiple endocrine neoplasia type 1 is overactivity of the parathyroid glands (hyperparathyroidism). Hyperparathyroidism disrupts the normal balance of calcium in the blood, which can lead to kidney stones, thinning of bones, nausea and vomiting, high blood pressure (hypertension), weakness, and fatigue.The most common sign of multiple endocrine neoplasia type 2 is a form of thyroid cancer called medullary thyroid carcinoma. Some people with this disorder also develop a pheochromocytoma, which is an adrenal gland tumor that can cause dangerously high blood pressure. Multiple endocrine neoplasia type 2 is divided into three subtypes: type 2A, type 2B (formerly called type 3), and familial medullary thyroid carcinoma (FMTC). These subtypes differ in their characteristic signs and symptoms and risk of specific tumors; for example, hyperparathyroidism occurs only in type 2A, and medullary thyroid carcinoma is the only feature of FMTC. The signs and symptoms of multiple endocrine neoplasia type 2 are relatively consistent within any one family.Multiple endocrine neoplasia type 4 appears to have signs and symptoms similar to those of type 1, although it is caused by mutations in a different gene. Hyperparathyroidism is the most common feature, followed by tumors of the pituitary gland, additional endocrine glands, and other organs.
[Learn More]