2027 ICD-10-CM Diagnosis Code E25Adrenogenital disorders

ICD-10-CM Codes›E00–E89›E20-E35›E25

ICD-10-CM E25
CMSSource: CMS FY 2027 ICD-10-CM dataset · Effective Oct 1, 2026 – Sep 30, 2027

E25 is a non-billable ICD-10-CM category code for adrenogenital disorders, so it cannot be submitted on claims. Use a more specific code from this category instead, such as E25.0, E25.8, and E25.9.

Code Identity

ICD-10-CM Code
E25
Billable Status
No — Non-Billable Category
Code Describes
Adrenogenital disorders
Short Description
Adrenogenital disorders
Same as the full description in the CMS dataset.
Chapter
E20-E35
Disorders of other endocrine glands

Code Classification

ChapterE00–E89Endocrine, nutritional and metabolic diseases
SectionE20-E35Disorders of other endocrine glands
CategoryE25Adrenogenital disorders
This CodeE25Adrenogenital disorders

Specific Coding for Adrenogenital disordersOverview

Non-specific codes like E25 require more characters. Use one of these billable codes instead:

  • Use E25.0 for Congenital adrenogenital disorders associated with enzyme deficiency

  • Use E25.8 for Other adrenogenital disorders

  • Use E25.9 for Adrenogenital disorder, unspecified

Instructional NotesGuidance

Instructions from the official ICD-10-CM Tabular List that apply to E25: its own notes plus those printed at block E20-E35 and Chapter 4. A note printed at a category, block or chapter applies to every code under it.

Includes

Further defines, or gives examples of, the content of the category.

  • adrenogenital syndromes, virilizing or feminizing, whether acquired or due to adrenal hyperplasia consequent on inborn enzyme defects in hormone synthesis
  • Female adrenal pseudohermaphroditism
  • Female heterosexual precocious pseudopuberty
  • Male isosexual precocious pseudopuberty
  • Male macrogenitosomia praecox
  • Male sexual precocity with adrenal hyperplasia
  • Male virilization (female)

Excludes1

Not coded here: the excluded code is never reported together with this one, unless the two conditions are unrelated.

On E25 itself
  • indeterminate sex and pseudohermaphroditism (Q56)
  • chromosomal abnormalities (Q90-Q99)
From Block E20-E35 Disorders of other endocrine glands applies to 99 codes
From Chapter 4 (E00-E89) Endocrine, nutritional and metabolic diseases applies to 973 codes
  • transitory endocrine and metabolic disorders specific to newborn (P70-P74)

Notes

General instructions on how these codes are used.

From Chapter 4 (E00-E89) Endocrine, nutritional and metabolic diseases applies to 973 codes
  • All neoplasms, whether functionally active or not, are classified in Chapter 2. Appropriate codes in this chapter (i.e. E05.8, E07.0, E16-E31, E34.-) may be used as additional codes to indicate either functional activity by neoplasms and ectopic endocrine tissue or hyperfunction and hypofunction of endocrine glands associated with neoplasms and other conditions classified elsewhere.

Source: CMS ICD-10-CM Tabular List. How to read instructional notes.

Referenced in Other NotesGuidance

Instructional notes printed at other codes that name E25, its category, or a range that includes it.

Excludes1 4

These codes carry an Excludes1 note naming E25: they are not reported together with it, unless the two conditions are unrelated.

  • E30.1 Precocious puberty
    female heterosexual precocious pseudopuberty (E25.-)
  • E30.1 Precocious puberty
    male isosexual precocious pseudopuberty (E25.-)
  • Q56 Indeterminate sex and pseudohermaphroditism
    female pseudohermaphroditism with adrenocortical disorder (E25.-)
  • Q89.1 Congenital malformations of adrenal gland
    adrenogenital disorders (E25.-)

Code First 1

These codes say to code first a condition named in the note, and E25 is one of the conditions named.

  • G63 Polyneuropathy in diseases classified elsewhere
    endocrine disease, except diabetes (E00-E07, E15-E16, E20-E34) names E20-E34, which includes this code

Notes 1

These notes mention E25.

  • Chapter 4 (E00-E89) Endocrine, nutritional and metabolic diseases
    All neoplasms, whether functionally active or not, are classified in Chapter 2. Appropriate codes in this chapter (i.e. E05.8, E07.0, E16-E31, E34.-) may be used as additional codes to indicate either functional activity by neoplasms and ectopic endocrine tissue or hyperfunction and hypofunction of endocrine glands associated with neoplasms and other conditions classified elsewhere. names E16-E31, which includes this code

Patient EducationClinical

Adrenal Gland Disorders

Your adrenal glands are two small organs that sit on top of each kidney. The adrenal glands make different types of hormones you need to stay alive and healthy. Hormones are chemicals that travel in your bloodstream and control how different parts of your body work.

The full article covers:

  • What are adrenal glands?
  • What are adrenal gland disorders?
  • What causes adrenal gland disorders?
  • How are adrenal gland disorders diagnosed?
  • What are the treatments for adrenal gland disorders?

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2026No changes
FY 2027CurrentCurrent code set, no changesEffective October 1, 2026 through September 30, 2027.

Questions About E25Overview

What is the ICD-10 code for adrenogenital disorders?

E25 is the ICD-10-CM category for adrenogenital disorders, but it is a non-billable header: claims need a more specific code from this category, listed on this page.

Is E25 (Adrenogenital disorders) a billable code?

No. This is a category header that groups the codes for adrenogenital disorders, and headers cannot be submitted on claims. Claims for adrenogenital disorders need a more specific code from this category, such as E25.0, E25.8, and E25.9.

Can E25 be reported with Q56?

Not as a rule. The Excludes1 note on E25 lists "indeterminate sex and pseudohermaphroditism (Q56)". An Excludes1 note means the excluded code is never reported together with this one; the only exception is when the two conditions are unrelated to each other (Official Guidelines, Section I.A.12.a).