2027 ICD-10-CM Diagnosis Code E28.2Polycystic ovarian syndrome

ICD-10-CM Codes›E00–E89›E20-E35›E28

ICD-10-CM E28.2
CMSSource: CMS FY 2027 ICD-10-CM dataset · Effective Oct 1, 2026 – Sep 30, 2027

E28.2 is a billable ICD-10-CM diagnosis code for polycystic ovarian syndrome. It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027) and groups to MS-DRG 742 through 743, 760 through 761. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Other specified and unspecified endocrine disorders.

Code Identity

ICD-10-CM Code
E28.2
Billable Status
Yes — Valid for Submission
Code Describes
Polycystic ovarian syndrome
Short Description
Polycystic ovarian syndrome
Same as the full description in the CMS dataset.
Parent Code
E28
Ovarian dysfunction

Code Classification

ChapterE00–E89Endocrine, nutritional and metabolic diseases
SectionE20-E35Disorders of other endocrine glands
CategoryE28Ovarian dysfunction
This CodeE28.2Polycystic ovarian syndrome

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Androgenetic alopecia in association with polycystic ovaries
  • Cyst of bilateral ovaries
  • Diffuse alopecia
  • Endocrine alopecia
  • Hyperandrogenization syndrome
  • Isosexual virilization
  • Male pattern alopecia
  • Polycystic bilateral ovaries
  • Polycystic left ovary
  • Polycystic ovary
  • Polycystic ovary syndrome
  • Polycystic ovary syndrome of bilateral ovaries
  • Polycystic ovary syndrome of left ovary
  • Polycystic ovary syndrome of right ovary
  • Polycystic right ovary

Instructional NotesGuidance

Instructions from the official ICD-10-CM Tabular List that apply to E28.2: its own notes plus those printed at E28, block E20-E35, and Chapter 4. A note printed at a category, block or chapter applies to every code under it.

Applicable To

Conditions this code is used for: synonyms of the title or, for "other specified" codes, the conditions assigned to it. The list is not exhaustive.

  • Sclerocystic ovary syndrome
  • Stein-Leventhal syndrome

Excludes1

Not coded here: the excluded code is never reported together with this one, unless the two conditions are unrelated.

From E28 Ovarian dysfunction applies to 8 codes
  • isolated gonadotropin deficiency (E23.0)
  • postprocedural ovarian failure (E89.4-)
From Block E20-E35 Disorders of other endocrine glands applies to 99 codes
From Chapter 4 (E00-E89) Endocrine, nutritional and metabolic diseases applies to 973 codes
  • transitory endocrine and metabolic disorders specific to newborn (P70-P74)

Notes

General instructions on how these codes are used.

From Chapter 4 (E00-E89) Endocrine, nutritional and metabolic diseases applies to 973 codes
  • All neoplasms, whether functionally active or not, are classified in Chapter 2. Appropriate codes in this chapter (i.e. E05.8, E07.0, E16-E31, E34.-) may be used as additional codes to indicate either functional activity by neoplasms and ectopic endocrine tissue or hyperfunction and hypofunction of endocrine glands associated with neoplasms and other conditions classified elsewhere.

Source: CMS ICD-10-CM Tabular List. How to read instructional notes.

Referenced in Other NotesGuidance

Instructional notes printed at other codes that name E28.2, its category, or a range that includes it.

Excludes1 3

These codes carry an Excludes1 note naming E28.2: they are not reported together with it, unless the two conditions are unrelated.

  • N83.2 Other and unspecified ovarian cysts
    polycystic ovarian syndrome (E28.2)
  • N83.2 Other and unspecified ovarian cysts
    Stein-Leventhal syndrome (E28.2)
  • N91 Absent, scanty and rare menstruation
    ovarian dysfunction (E28.-) names E28.-, which includes this code

Excludes2 1

These codes carry an Excludes2 note naming E28.2: its condition is not part of those codes, and both may be reported when the patient has both.

  • N97 Female infertility
    Stein-Leventhal syndrome (E28.2)

Code First 1

These codes say to code first a condition named in the note, and E28.2 is one of the conditions named.

  • G63 Polyneuropathy in diseases classified elsewhere
    endocrine disease, except diabetes (E00-E07, E15-E16, E20-E34) names E20-E34, which includes this code

Notes 1

These notes mention E28.2.

  • Chapter 4 (E00-E89) Endocrine, nutritional and metabolic diseases
    All neoplasms, whether functionally active or not, are classified in Chapter 2. Appropriate codes in this chapter (i.e. E05.8, E07.0, E16-E31, E34.-) may be used as additional codes to indicate either functional activity by neoplasms and ectopic endocrine tissue or hyperfunction and hypofunction of endocrine glands associated with neoplasms and other conditions classified elsewhere. names E16-E31, which includes this code

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR END015
Other specified and unspecified endocrine disorders
Default principal diagnosis: inpatient Yes · outpatient Yes

Clinical InformationClinical

  • Polycystic Ovary Syndrome

    a complex disorder characterized by infertility, hirsutism; obesity; and various menstrual disturbances such as oligomenorrhea; amenorrhea; anovulation. polycystic ovary syndrome is usually associated with bilateral enlarged ovaries studded with atretic follicles, not with cysts. the term, polycystic ovary, is misleading.

Patient EducationClinical

Polycystic Ovary Syndrome

Polycystic ovary syndrome (PCOS), also known as polyendocrine metabolic ovary syndrome (PMOS), is the name of a hormonal disorder. PCOS affects the ovaries, as well as many other parts of the body.

The full article covers:

  • What is polycystic ovary syndrome (PCOS)?
  • What causes polycystic ovary syndrome (PCOS)?
  • What are the symptoms of polycystic ovary syndrome (PCOS)?
  • What other health problems are linked to polycystic ovary syndrome (PCOS)?
  • How is polycystic ovary syndrome (PCOS) diagnosed?
  • What are the treatments for polycystic ovary syndrome (PCOS)?

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert E28.2 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
256.4 Polycystic ovaries
Exact Match The mapping is direct, with no qualifiers.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2026No changes
FY 2027CurrentCurrent code set, no changesEffective October 1, 2026 through September 30, 2027.

Questions About E28.2Overview

What is the ICD-10 code for polycystic ovarian syndrome?

The ICD-10-CM code for polycystic ovarian syndrome is E28.2 (sometimes written as E282). It is billable on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

Is E28.2 (Ovarian dysfunction) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report polycystic ovarian syndrome on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

What MS-DRG does E28.2 group to?

When polycystic ovarian syndrome is the principal diagnosis on an inpatient stay, it groups to MS-DRG 742, 743, 760, 761, with relative weights from 0.7039 to 1.8448 depending on complications. Higher weights mean higher Medicare reimbursement.

Can E28.2 be reported with E23.0?

Not as a rule. The Excludes1 note at E28, which applies to E28.2, lists "isolated gonadotropin deficiency (E23.0)". An Excludes1 note means the excluded code is never reported together with this one; the only exception is when the two conditions are unrelated to each other (Official Guidelines, Section I.A.12.a).

What is the ICD-9 equivalent of E28.2?

Under the General Equivalence Mappings, polycystic ovarian syndrome converts to ICD-9-CM 256.4 (polycystic ovaries). The mapping is a direct match.