2026 ICD-10-CM Diagnosis Code E28.2Polycystic ovarian syndrome

ICD-10-CM CodesE00–E89E20-E35E28

ICD-10-CM E28.2
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

E28.2 is a billable ICD-10-CM diagnosis code for polycystic ovarian syndrome. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 742 through 743, 760 through 761. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Other specified and unspecified endocrine disorders.

Code Identity

ICD-10-CM Code
E28.2
Billable Status
Yes — Valid for Submission
Code Describes
Polycystic ovarian syndrome
Short Description
Polycystic ovarian syndrome
Same as the full description in the CMS dataset.
Parent Code
Ovarian dysfunction

Code Classification

ChapterE00–E89Endocrine, nutritional and metabolic diseases
SectionE20-E35Disorders of other endocrine glands
CategoryE28Ovarian dysfunction
This CodeE28.2Polycystic ovarian syndrome

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Androgenetic alopecia in association with polycystic ovaries
  • Cyst of bilateral ovaries
  • Diffuse alopecia
  • Endocrine alopecia
  • Hyperandrogenization syndrome
  • Isosexual virilization
  • Male pattern alopecia
  • Polycystic bilateral ovaries
  • Polycystic left ovary
  • Polycystic ovary
  • Polycystic ovary syndrome
  • Polycystic ovary syndrome of bilateral ovaries
  • Polycystic ovary syndrome of left ovary
  • Polycystic ovary syndrome of right ovary
  • Polycystic right ovary

Tabular List NotesGuidance

Coding notes and annotation back-references applicable to this code.

Inclusion Terms

  • Sclerocystic ovary syndrome
  • Stein-Leventhal syndrome

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Disease, diseased
      • ovary (noninflammatory)
        • polycystic
    • Disease, diseased
      • polycystic
        • ovary, ovaries
    • Infertility
      • female
        • associated with
          • Stein-Leventhal syndrome
    • Infertility
      • female
        • due to
          • Stein-Leventhal syndrome
    • Polycystic(disease)
      • ovary, ovaries
    • Sclerocystic ovary syndrome
    • Stein-Leventhal syndrome
    • Stein's syndrome
    • Syndrome
      • bilateral polycystic ovarian
    • Syndrome
      • ovary
        • polycystic
    • Syndrome
      • ovary
        • sclerocystic
    • Syndrome
      • sclerocystic ovary
    • Syndrome
      • Stein-Leventhal
    • Syndrome
      • Stein's
    • Virilization(female) (suprarenal)
      • isosexual

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR END015
Other specified and unspecified endocrine disorders
Default principal diagnosis: inpatient Yes · outpatient Yes

Clinical InformationClinical

  • Polycystic Ovary Syndrome

    a complex disorder characterized by infertility, hirsutism; obesity; and various menstrual disturbances such as oligomenorrhea; amenorrhea; anovulation. polycystic ovary syndrome is usually associated with bilateral enlarged ovaries studded with atretic follicles, not with cysts. the term, polycystic ovary, is misleading.
  • Polycystic Ovary Syndrome

    a disorder that manifests as multiple cysts on the ovaries. it results in hormonal imbalances and leads to irregular and abnormal menstrual periods, excess growth of hair, acne eruptions and obesity.
  • Polycystic Ovary Syndrome|PCOS|PCOS|Polycystic Ovarian Disease|Polycystic Ovarian Syndrome (PCOS)|Stein-Leventhal Syndrome|Stein-Leventhal Syndrome|polycystic ovary syndrome

    a disorder that manifests as multiple cysts on the ovaries. it results in hormonal imbalances and leads to irregular and abnormal menstrual periods, excess growth of hair, acne eruptions and obesity.

Patient EducationClinical

Polycystic Ovary Syndrome

Polycystic ovary syndrome (PCOS) is the name for set of symptoms that are related to an imbalance of hormones. PCOS affects the ovaries, as well as many other parts of the body.

The full article covers:

  • What is polycystic ovary syndrome (PCOS)?
  • What causes polycystic ovary syndrome (PCOS)?
  • What are the symptoms of polycystic ovary syndrome (PCOS)?
  • What other health problems are linked to polycystic ovary syndrome (PCOS)?
  • How is polycystic ovary syndrome (PCOS) diagnosed?
  • What are the treatments for polycystic ovary syndrome (PCOS)?

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert E28.2 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
256.4 Polycystic ovaries
Exact Match The mapping is direct, with no qualifiers.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About E28.2Overview

Is E28.2 (Ovarian dysfunction) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report polycystic ovarian syndrome on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What MS-DRG does E28.2 group to?

When polycystic ovarian syndrome is the principal diagnosis on an inpatient stay, it groups to MS-DRG 742, 743, 760, 761, with relative weights from 0.5696 to 1.8348 depending on complications. Higher weights mean higher Medicare reimbursement.

What is the ICD-9 equivalent of E28.2?

Under the General Equivalence Mappings, polycystic ovarian syndrome converts to ICD-9-CM 256.4 (polycystic ovaries). The mapping is a direct match.

Footnotes

[1] Chronic - a chronic condition code indicates a condition lasting 12 months or longer and its effect on the patient based on one or both of the following criteria:

  • The condition results in the need for ongoing intervention with medical products,treatment, services, and special equipment
  • The condition places limitations on self-care, independent living, and social interactions.