2024 ICD-10-CM Diagnosis Code E27.49

Other adrenocortical insufficiency

ICD-10-CM Code:
E27.49
ICD-10 Code for:
Other adrenocortical insufficiency
Is Billable?
Yes - Valid for Submission
Chronic Condition Indicator: [1]
Chronic
Code Navigator:

Code Classification

  • Endocrine, nutritional and metabolic diseases
    (E00–E89)
    • Disorders of other endocrine glands
      (E20-E35)
      • Other disorders of adrenal gland
        (E27)

E27.49 is a billable diagnosis code used to specify a medical diagnosis of other adrenocortical insufficiency. The code is valid during the current fiscal year for the submission of HIPAA-covered transactions from October 01, 2023 through September 30, 2024.

Approximate Synonyms

The following clinical terms are approximate synonyms or lay terms that might be used to identify the correct diagnosis code:

  • Achalasia of esophagus
  • ACTH deficiency
  • ACTH deficiency
  • Adrenal atrophy
  • Adrenal calcification
  • Adrenal cortical hypofunction due to interruption of corticosteroid therapy
  • Adrenal gland hematoma
  • Adrenal hemorrhage
  • Adrenal infarction
  • Adrenal insufficiency due to adrenal metastasis
  • Adrenal necrosis
  • Adrenocortical hemorrhage
  • Adrenocorticotropic hormone resistance syndrome
  • Adrenocorticotropic hormone resistance syndrome
  • Aldosterone deficiency
  • Aldosterone deficiency
  • Aldosterone deficiency
  • Aldosterone deficiency
  • Aldosterone deficiency
  • Aldosterone deficiency
  • Atrophy of adrenal cortex
  • Autonomic neuropathy due to Allgrove syndrome
  • Congenital achalasia of esophagus
  • Congenital isolated adrenocorticotropic hormone deficiency
  • Degeneration of adrenal gland
  • Degeneration of adrenal gland
  • Familial hyperreninemic hypoaldosteronism type 1A
  • Familial hyperreninemic hypoaldosteronism type 1B
  • Familial hyperreninemic hypoaldosteronism type 2
  • Familial hypoaldosteronism
  • Generalized glucocorticoid resistance syndrome
  • Glucocorticoid deficiency with achalasia
  • Hereditary glucocorticoid resistance
  • Hyperkalemic renal tubular acidosis
  • Hyperreninemic hypoaldosteronism
  • Hypoadrenalism due to paracoccidioidomycosis
  • Hypocortisolism secondary to another disorder
  • Hyporeninemic hypoaldosteronism
  • Injury of adrenal gland
  • Injury of adrenal gland
  • Isolated corticotropin deficiency
  • Mineralocorticoid deficiency
  • Pituitary thyroid hormone resistance
  • Pituitary thyroid hormone resistance
  • Primary adrenocortical insufficiency
  • Primary adrenocortical insufficiency
  • Retroperitoneal hematoma
  • Thyroid hormone resistance syndrome
  • Thyroid hormone resistance syndrome

Clinical Classification

Clinical Information

  • Thyroid Hormone Resistance Syndrome

    an inherited autosomal recessive trait, characterized by peripheral resistance to thyroid hormones and the resulting elevation in serum levels of thyroxine and triiodothyronine. this syndrome is caused by mutations of gene thrb encoding the thyroid hormone receptors beta in target cells. hypothyroidism in these patients is partly overcome by the increased thyroid hormone levels.
  • Hyperreninemic Hypoaldosteronism

    hypoaldosteronism characterized by impaired secretion of aldosterone, despite increased renin activity. this condition may be caused by chronic or critical illness, aldosterone synthase deficiency or other genetic conditions.
  • Adrenal Hemorrhage

    hemorrhage and necrosis of the adrenal gland tissue. bilateral and extensive hemorrhage may lead to acute adrenal insufficiency, shock, and death.

Tabular List of Diseases and Injuries

The following annotation back-references are applicable to this diagnosis code. The Tabular List of Diseases and Injuries is a list of ICD-10-CM codes, organized "head to toe" into chapters and sections with coding notes and guidance for inclusions, exclusions, descriptions and more.


Inclusion Terms

Inclusion Terms
These terms are the conditions for which that code is to be used. The terms may be synonyms of the code title, or, in the case of "other specified" codes, the terms are a list of the various conditions assigned to that code. The inclusion terms are not necessarily exhaustive. Additional terms found only in the Alphabetic Index may also be assigned to a code.
  • Adrenal hemorrhage
  • Adrenal infarction

Index to Diseases and Injuries References

The following annotation back-references for this diagnosis code are found in the injuries and diseases index. The Index to Diseases and Injuries is an alphabetical listing of medical terms, with each term mapped to one or more ICD-10-CM code(s).

Convert E27.49 to ICD-9-CM

  • ICD-9-CM Code: 255.41 - Glucocorticoid deficient
    Approximate Flag - The approximate mapping means there is not an exact match between the ICD-10 and ICD-9 codes and the mapped code is not a precise representation of the original code.
  • ICD-9-CM Code: 255.42 - Mineralcorticoid defcnt
    Approximate Flag - The approximate mapping means there is not an exact match between the ICD-10 and ICD-9 codes and the mapped code is not a precise representation of the original code.

Patient Education


Addison Disease

Your adrenal glands are just above your kidneys. The outside layer of these glands makes hormones that help your body respond to stress and regulate your blood pressure and water and salt balance. Addison disease happens if the adrenal glands don't make enough of these hormones.

A problem with your immune system usually causes Addison disease. The immune system mistakenly attacks your own tissues, damaging your adrenal glands. Other causes include infections and cancer.

Symptoms include:

  • Weight loss
  • Muscle weakness
  • Fatigue that gets worse over time
  • Low blood pressure
  • Patchy or dark skin

Lab tests can confirm that you have Addison disease. If you don't treat it, it can be fatal. You will need to take hormone pills for the rest of your life. If you have Addison disease, you should carry an emergency ID. It should say that you have the disease, list your medicines and say how much you need in an emergency.

NIH: National Institute of Diabetes and Digestive and Kidney Diseases


[Learn More in MedlinePlus]

Code History

  • FY 2024 - No Change, effective from 10/1/2023 through 9/30/2024
  • FY 2023 - No Change, effective from 10/1/2022 through 9/30/2023
  • FY 2022 - No Change, effective from 10/1/2021 through 9/30/2022
  • FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021
  • FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020
  • FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
  • FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
  • FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
  • FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016. This was the first year ICD-10-CM was implemented into the HIPAA code set.

Footnotes

[1] Chronic - a chronic condition code indicates a condition lasting 12 months or longer and its effect on the patient based on one or both of the following criteria:

  • The condition results in the need for ongoing intervention with medical products,treatment, services, and special equipment
  • The condition places limitations on self-care, independent living, and social interactions.