Valid for Submission
E27.40 is a billable diagnosis code used to specify a medical diagnosis of unspecified adrenocortical insufficiency. The code E27.40 is valid during the fiscal year 2022 from October 01, 2021 through September 30, 2022 for the submission of HIPAA-covered transactions.
The ICD-10-CM code E27.40 might also be used to specify conditions or terms like 46,xy disorder of sex development, adrenal insufficiency due to cyp11a1 deficiency, acth deficiency, adrenal cortical hypofunction, adrenal medullary insufficiency, aldosterone deficiency , congenital hypoplasia of adrenal gland, etc.
Unspecified diagnosis codes like E27.40 are acceptable when clinical information is unknown or not available about a particular condition. Although a more specific code is preferable, unspecified codes should be used when such codes most accurately reflect what is known about a patient's condition. Specific diagnosis codes should not be used if not supported by the patient's medical record.
Tabular List of Diseases and Injuries
The Tabular List of Diseases and Injuries is a list of ICD-10 codes, organized "head to toe" into chapters and sections with coding notes and guidance for inclusions, exclusions, descriptions and more. The following references are applicable to the code E27.40:
Inclusion TermsInclusion Terms
These terms are the conditions for which that code is to be used. The terms may be synonyms of the code title, or, in the case of "other specified" codes, the terms are a list of the various conditions assigned to that code. The inclusion terms are not necessarily exhaustive. Additional terms found only in the Alphabetic Index may also be assigned to a code.
- Adrenocortical insufficiency NOS
Index to Diseases and Injuries
The Index to Diseases and Injuries is an alphabetical listing of medical terms, with each term mapped to one or more ICD-10 code(s). The following references for the code E27.40 are found in the index:
- - Hypoadrenalism, hypoadrenia - E27.40
- - Hypoadrenocorticism - E27.40
- - Hypoaldosteronism - E27.40
The following clinical terms are approximate synonyms or lay terms that might be used to identify the correct diagnosis code:
- 46,XY disorder of sex development, adrenal insufficiency due to CYP11A1 deficiency
- ACTH deficiency
- Adrenal cortical hypofunction
- Adrenal medullary insufficiency
- Aldosterone deficiency
- Congenital hypoplasia of adrenal gland
- Epinephrine deficiency
- Familial adrenocortical hypoplasia
- Hypoadrenergic postural hypotension
- Idiopathic ACTH deficiency
- Orthostatic hypotension
- ADDISON DISEASE-. an adrenal disease characterized by the progressive destruction of the adrenal cortex resulting in insufficient production of aldosterone and hydrocortisone. clinical symptoms include anorexia; nausea; weight loss; muscle weakness; and hyperpigmentation of the skin due to increase in circulating levels of acth precursor hormone which stimulates melanocytes.
Diagnostic Related Groups - MS-DRG Mapping
|MS-DRG||MS-DRG Title||MCD||Relative Weight|
|643||ENDOCRINE DISORDERS WITH MCC||10||1.6633|
|644||ENDOCRINE DISORDERS WITH CC||10||1.0183|
|645||ENDOCRINE DISORDERS WITHOUT CC/MCC||10||0.7678|
The relative weight of a diagnostic related group determines the reimbursement rate based on the severity of a patient's illness and the associated cost of care during hospitalization.
Convert E27.40 to ICD-9 Code
The General Equivalency Mapping (GEM) crosswalk indicates an approximate mapping between the ICD-10 code E27.40 its ICD-9 equivalent. The approximate mapping means there is not an exact match between the ICD-10 code and the ICD-9 code and the mapped code is not a precise representation of the original code.
Information for Patients
Your adrenal glands are just above your kidneys. The outside layer of these glands makes hormones that help your body respond to stress and regulate your blood pressure and water and salt balance. Addison disease happens if the adrenal glands don't make enough of these hormones.
A problem with your immune system usually causes Addison disease. The immune system mistakenly attacks your own tissues, damaging your adrenal glands. Other causes include infections and cancer.
- Weight loss
- Muscle weakness
- Fatigue that gets worse over time
- Low blood pressure
- Patchy or dark skin
Lab tests can confirm that you have Addison disease. If you don't treat it, it can be fatal. You will need to take hormone pills for the rest of your life. If you have Addison disease, you should carry an emergency ID. It should say that you have the disease, list your medicines and say how much you need in an emergency.
NIH: National Institute of Diabetes and Digestive and Kidney Diseases
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