ICD-10-CM Code E27.8

Other specified disorders of adrenal gland

Version 2020 Billable Code

Valid for Submission

E27.8 is a billable code used to specify a medical diagnosis of other specified disorders of adrenal gland. The code is valid for the year 2020 for the submission of HIPAA-covered transactions. The ICD-10-CM code E27.8 might also be used to specify conditions or terms like abnormality of cortisol-binding globulin, adrenal cyst, adrenal gland cytomegaly, adrenal hyperplasia, adrenal hyperplasia, adrenal hypertrophy or hyperplasia, etc

Short Description:Other specified disorders of adrenal gland
Long Description:Other specified disorders of adrenal gland

Tabular List of Diseases and Injuries

The Tabular List of Diseases and Injuries is a list of ICD-10 codes, organized "head to toe" into chapters and sections with guidance for inclusions, exclusions, descriptions and more. The following references are applicable to the code E27.8:

Inclusion Terms

Inclusion Terms
These terms are the conditions for which that code is to be used. The terms may be synonyms of the code title, or, in the case of "other specified" codes, the terms are a list of the various conditions assigned to that code. The inclusion terms are not necessarily exhaustive. Additional terms found only in the Alphabetic Index may also be assigned to a code.
  • Abnormality of cortisol-binding globulin

Index to Diseases and Injuries

The Index to Diseases and Injuries is an alphabetical listing of medical terms, with each term mapped to one or more ICD-10 code(s). The following references for the code E27.8 are found in the index:


The following clinical terms are approximate synonyms or lay terms that might be used to identify the correct diagnosis code:

  • Abnormality of cortisol-binding globulin
  • Adrenal cyst
  • Adrenal gland cytomegaly
  • Adrenal hyperplasia
  • Adrenal hyperplasia
  • Adrenal hypertrophy or hyperplasia
  • Adrenocortical hyperplasia
  • Adrenocortical hyperplasia
  • Aldosterone disorder
  • Bilateral mass of adrenal glands
  • Capsular extrusion of adrenal cortex
  • Corticosteroid-binding globulin deficiency
  • Cortisol binding globulin high
  • Cortisol binding globulin low
  • Disorder of cortisol-cortisone shuttle
  • Enlarged adrenal gland
  • Hyperaldosteronism with nodular hyperplasia of adrenal cortex
  • Hypercortisolism due to macronodular adrenal hyperplasia
  • Macronodular adrenal hyperplasia
  • Mass of left adrenal gland
  • Mass of right adrenal gland
  • Micronodular adrenal hyperplasia
  • Nodular adrenal cortex
  • Pigmented micronodular adrenal hyperplasia
  • Precocious puberty with adrenal hyperplasia
  • Primary pigmented nodular adrenocortical disease
  • Primary unilateral adrenal hyperplasia
  • Small adrenal gland
  • Syndrome of apparent mineralocorticoid excess

Diagnostic Related Groups

The ICD-10 code E27.8 is grouped in the following groups for version MS-DRG V37.0 What are Diagnostic Related Groups?
The Diagnostic Related Groups (DRGs) are a patient classification scheme which provides a means of relating the type of patients a hospital treats. The DRGs divides all possible principal diagnoses into mutually exclusive principal diagnosis areas referred to as Major Diagnostic Categories (MDC).
applicable from 10/01/2019 through 09/30/2020.


Convert E27.8 to ICD-9

  • 255.8 - Adrenal disorder NEC (Approximate Flag)

Code Classification

  • Endocrine, nutritional and metabolic diseases (E00–E90)
    • Disorders of other endocrine glands (E20-E35)
      • Other disorders of adrenal gland (E27)

Code History

  • FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016
    (First year ICD-10-CM implemented into the HIPAA code set)
  • FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
  • FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
  • FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
  • FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020

Information for Patients

Adrenal Gland Disorders

The adrenal glands are small glands located on top of each kidney. They produce hormones that you can't live without, including sex hormones and cortisol. Cortisol helps you respond to stress and has many other important functions.

With adrenal gland disorders, your glands make too much or not enough hormones. In Cushing's syndrome, there's too much cortisol, while with Addison's disease, there is too little. Some people are born unable to make enough cortisol.

Causes of adrenal gland disorders include

  • Genetic mutations
  • Tumors including pheochromocytomas
  • Infections
  • A problem in another gland, such as the pituitary, which helps to regulate the adrenal gland
  • Certain medicines

Treatment depends on which problem you have. Surgery or medicines can treat many adrenal gland disorders.

NIH: National Institute of Child Health and Human Development

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