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  6. 2026 ICD-10-CM Code E28

2026 ICD-10-CM Diagnosis Code E28

Ovarian dysfunction

ICD-10-CM Code:
E28
ICD-10 Code for:
Ovarian dysfunction
Is Billable?
Not Valid for Submission
Code Navigator:

E28 is a non-specific and non-billable diagnosis code code, consider using a code with a higher level of specificity for a diagnosis of ovarian dysfunction. The code is not specific and is NOT valid for the year 2026 for the submission of HIPAA-covered transactions. Category or Header define the heading of a category of codes that may be further subdivided by the use of 4th, 5th, 6th or 7th characters.

Specific Coding Applicable to Ovarian dysfunction

Non-specific codes like E28 require more digits to indicate the appropriate level of specificity. Consider using any of the following ICD-10-CM codes with a higher level of specificity when coding for ovarian dysfunction:

  • Use E28.0 for Estrogen excess - BILLABLE CODE

  • Use E28.1 for Androgen excess - BILLABLE CODE

  • Use E28.2 for Polycystic ovarian syndrome - BILLABLE CODE

  • E28.3 for Primary ovarian failure - NON-BILLABLE CODE

  • E28.31 for Premature menopause - NON-BILLABLE CODE

  • Use E28.39 for Other primary ovarian failure - BILLABLE CODE

  • Use E28.8 for Other ovarian dysfunction - BILLABLE CODE

  • Use E28.9 for Ovarian dysfunction, unspecified - BILLABLE CODE

Code Classification

  • Endocrine, nutritional and metabolic diseases
    E00–E89
    • Disorders of other endocrine glands
      E20-E35
      • Ovarian dysfunction
        E28

Tabular List of Diseases and Injuries

The following annotation back-references are applicable to this diagnosis code. The Tabular List of Diseases and Injuries is a list of ICD-10-CM codes, organized "head to toe" into chapters and sections with coding notes and guidance for inclusions, exclusions, descriptions and more.


Type 1 Excludes

Type 1 Excludes
A type 1 excludes note is a pure excludes note. It means "NOT CODED HERE!" An Excludes1 note indicates that the code excluded should never be used at the same time as the code above the Excludes1 note. An Excludes1 is used when two conditions cannot occur together, such as a congenital form versus an acquired form of the same condition.
  • isolated gonadotropin deficiency E23.0
  • postprocedural ovarian failure E89.4

Patient Education


Ovarian Disorders

What are ovaries?

The ovaries are a pair of female reproductive glands that make eggs and female hormones. Women have one ovary on each side of the uterus (where a fetus grows during pregnancy). Each ovary is about the size and shape of an almond.

Ovaries play a role in menstruation, pregnancy, and menopause. Your ovaries:

  • Produce and store eggs that are released during ovulation (when an egg leaves the ovary and travels into the fallopian tube). If a sperm fertilizes the egg, you can become pregnant.
  • Make the female hormones estrogen and progesterone.
  • Stop making those hormones and releasing eggs during menopause.

Some medical problems can affect the ovaries. These can cause various symptoms, and some ovarian disorders may need prompt treatment.

What are the types of ovarian disorders?

Some problems that can happen with the ovaries can include:

  • Ovarian cancer is when a cancerous tumor forms in the tissues of an ovary.
  • Ovarian cysts are fluid-filled sacs in or on an ovary.
  • Polycystic ovary syndrome (PCOS) is a set of symptoms related to an imbalance of hormones.
  • Primary ovarian insufficiency is when your ovaries stop working before age 40.
  • Ovarian torsion is a twisting of the ovary.
  • Endometriosis is when tissue like the lining in your uterus grows in other places in your body. It may affect the ovaries, fallopian tubes, and tissue lining the pelvis.
  • Pelvic inflammatory disease is an infection and inflammation of the uterus, ovaries, and other female reproductive organs.
  • Ovarian tumors.

What causes ovarian disorders?

Ovarian disorders can happen for different reasons depending on the condition. Sometimes the cause is unknown.

What are the symptoms of ovarian disorders?

Your symptoms may be different, depending on the problem with your ovaries. Some ovarian disorders, such as ovarian cysts, may cause few or even no symptoms. Other disorders may cause more severe symptoms. Symptoms can include:

  • Pelvic pain, which often happens during your period
  • Nausea or diarrhea
  • Vaginal bleeding that is between periods, very heavy, or longer than usual
  • Vaginal discharge
  • Painful menstrual cramps

How are ovarian disorders diagnosed?

To find out if you have a problem with your ovaries, your health care provider:

  • Will ask about your medical history, including your symptoms
  • Will ask about your family health history
  • Will do a physical exam, including a pelvic exam
  • May order imaging tests, or blood tests

What are the treatments for ovarian disorders?

Treatment depends on the ovarian disorder, your symptoms, overall health, and plans for pregnancy. Treatment can include medicines, such as pain relievers or hormonal birth control, lifestyle changes to reduce symptoms, or sometimes surgery. Ovarian cancer may require surgery, chemotherapy, or other targeted therapy.


[Learn More in MedlinePlus]

Code History

  • FY 2026 - No Change, effective from 10/1/2025 through 9/30/2026
  • FY 2025 - No Change, effective from 10/1/2024 through 9/30/2025
  • FY 2024 - No Change, effective from 10/1/2023 through 9/30/2024
  • FY 2023 - No Change, effective from 10/1/2022 through 9/30/2023
  • FY 2022 - No Change, effective from 10/1/2021 through 9/30/2022
  • FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021
  • FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020
  • FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
  • FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
  • FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
  • FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016. This was the first year ICD-10-CM was implemented into the HIPAA code set.