2027 ICD-10-CM Diagnosis Code E28Ovarian dysfunction

ICD-10-CM Codes›E00–E89›E20-E35›E28

ICD-10-CM E28
CMSSource: CMS FY 2027 ICD-10-CM dataset · Effective Oct 1, 2026 – Sep 30, 2027

E28 is a non-billable ICD-10-CM category code for ovarian dysfunction, so it cannot be submitted on claims. Use a more specific code from this category instead, such as E28.0, E28.1, E28.2, and E28.310.

Code Identity

ICD-10-CM Code
E28
Billable Status
No — Non-Billable Category
Code Describes
Ovarian dysfunction
Short Description
Ovarian dysfunction
Same as the full description in the CMS dataset.
Chapter
E20-E35
Disorders of other endocrine glands

Code Classification

ChapterE00–E89Endocrine, nutritional and metabolic diseases
SectionE20-E35Disorders of other endocrine glands
CategoryE28Ovarian dysfunction
This CodeE28Ovarian dysfunction

Specific Coding for Ovarian dysfunctionOverview

Non-specific codes like E28 require more characters. Use one of these billable codes instead:

  • Use E28.0 for Estrogen excess

  • Use E28.1 for Androgen excess

  • Use E28.2 for Polycystic ovarian syndrome

  • E28.3 for Primary ovarian failure

  • E28.31 for Premature menopause

  • Use E28.39 for Other primary ovarian failure

  • Use E28.8 for Other ovarian dysfunction

  • Use E28.9 for Ovarian dysfunction, unspecified

Instructional NotesGuidance

Instructions from the official ICD-10-CM Tabular List that apply to E28: its own notes plus those printed at block E20-E35 and Chapter 4. A note printed at a category, block or chapter applies to every code under it.

Excludes1

Not coded here: the excluded code is never reported together with this one, unless the two conditions are unrelated.

On E28 itself
  • isolated gonadotropin deficiency (E23.0)
  • postprocedural ovarian failure (E89.4-)
From Block E20-E35 Disorders of other endocrine glands applies to 99 codes
From Chapter 4 (E00-E89) Endocrine, nutritional and metabolic diseases applies to 973 codes
  • transitory endocrine and metabolic disorders specific to newborn (P70-P74)

Notes

General instructions on how these codes are used.

From Chapter 4 (E00-E89) Endocrine, nutritional and metabolic diseases applies to 973 codes
  • All neoplasms, whether functionally active or not, are classified in Chapter 2. Appropriate codes in this chapter (i.e. E05.8, E07.0, E16-E31, E34.-) may be used as additional codes to indicate either functional activity by neoplasms and ectopic endocrine tissue or hyperfunction and hypofunction of endocrine glands associated with neoplasms and other conditions classified elsewhere.

Source: CMS ICD-10-CM Tabular List. How to read instructional notes.

Referenced in Other NotesGuidance

Instructional notes printed at other codes that name E28, its category, or a range that includes it.

Excludes1 1

These codes carry an Excludes1 note naming E28: they are not reported together with it, unless the two conditions are unrelated.

  • N91 Absent, scanty and rare menstruation
    ovarian dysfunction (E28.-)

Code First 1

These codes say to code first a condition named in the note, and E28 is one of the conditions named.

  • G63 Polyneuropathy in diseases classified elsewhere
    endocrine disease, except diabetes (E00-E07, E15-E16, E20-E34) names E20-E34, which includes this code

Notes 1

These notes mention E28.

  • Chapter 4 (E00-E89) Endocrine, nutritional and metabolic diseases
    All neoplasms, whether functionally active or not, are classified in Chapter 2. Appropriate codes in this chapter (i.e. E05.8, E07.0, E16-E31, E34.-) may be used as additional codes to indicate either functional activity by neoplasms and ectopic endocrine tissue or hyperfunction and hypofunction of endocrine glands associated with neoplasms and other conditions classified elsewhere. names E16-E31, which includes this code

Patient EducationClinical

Ovarian Disorders

The ovaries are a pair of female reproductive glands that make eggs and female hormones. Women have one ovary on each side of the uterus (where a fetus grows during pregnancy). Each ovary is about the size and shape of an almond.

The full article covers:

  • What are ovaries?
  • What are the types of ovarian disorders?
  • What causes ovarian disorders?
  • What are the symptoms of ovarian disorders?
  • How are ovarian disorders diagnosed?
  • What are the treatments for ovarian disorders?

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2026No changes
FY 2027CurrentCurrent code set, no changesEffective October 1, 2026 through September 30, 2027.

Questions About E28Overview

What is the ICD-10 code for ovarian dysfunction?

E28 is the ICD-10-CM category for ovarian dysfunction, but it is a non-billable header: claims need a more specific code from this category, listed on this page.

Is E28 (Ovarian dysfunction) a billable code?

No. This is a category header that groups the codes for ovarian dysfunction, and headers cannot be submitted on claims. Claims for ovarian dysfunction need a more specific code from this category, such as E28.0, E28.1, and E28.2.

Can E28 be reported with E23.0?

Not as a rule. The Excludes1 note on E28 lists "isolated gonadotropin deficiency (E23.0)". An Excludes1 note means the excluded code is never reported together with this one; the only exception is when the two conditions are unrelated to each other (Official Guidelines, Section I.A.12.a).