2026 ICD-10-CM Diagnosis Code E27.9Disorder of adrenal gland, unspecified

ICD-10-CM Codes›E00–E89›E20-E35›E27

ICD-10-CM E27.9
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

E27.9 is a billable ICD-10-CM diagnosis code for disorder of adrenal gland, unspecified. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 643 through 645. Coders also document this condition as anemia of adrenal dysfunction. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Other specified and unspecified endocrine disorders.

Code Identity

ICD-10-CM Code
E27.9
Billable Status
Yes — Valid for Submission
Code Describes
Disorder of adrenal gland, unspecified
Short Description
Disorder of adrenal gland, unspecified
Same as the full description in the CMS dataset.
Parent Code
E27
Other disorders of adrenal gland

Code Classification

ChapterE00–E89Endocrine, nutritional and metabolic diseases
SectionE20-E35Disorders of other endocrine glands
CategoryE27Other disorders of adrenal gland
This CodeE27.9Disorder of adrenal gland, unspecified

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Anemia of adrenal dysfunction
  • Anemia of endocrine disorder
  • Complex adrenal endocrine disorder
  • Disorder of adrenal cortex
  • Disorder of adrenal gland
  • Disorder of adrenal medulla
  • Hypothalamic-adrenal dysfunction

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Disease, diseased
      • adrenal (capsule) (cortex) (gland) (medullary)
    • Disease, diseased
      • suprarenal (capsule) (gland)
    • Disorder(of)
      • adrenal (capsule) (gland) (medullary)
    • Dysadrenocortism
    • Dysfunction
      • adrenal
    • Dysfunction
      • suprarenal

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR END015
Other specified and unspecified endocrine disorders
Default principal diagnosis: inpatient Yes · outpatient Yes

Patient EducationClinical

Adrenal Gland Disorders

Your adrenal glands are two small organs that sit on top of each kidney. The adrenal glands make different types of hormones you need to stay alive and healthy. Hormones are chemicals that travel in your bloodstream and control how different parts of your body work.

The full article covers:

  • What are adrenal glands?
  • What are adrenal gland disorders?
  • What causes adrenal gland disorders?
  • How are adrenal gland disorders diagnosed?
  • What are the treatments for adrenal gland disorders?

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert E27.9 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
255.9 Adrenal disorder NOS
Exact Match The mapping is direct, with no qualifiers.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About E27.9Overview

Is E27.9 (Other disorders of adrenal gland) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report disorder of adrenal gland, unspecified on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What MS-DRG does E27.9 group to?

When disorder of adrenal gland, unspecified is the principal diagnosis on an inpatient stay, it groups to MS-DRG 643, 644, 645, with relative weights from 0.7683 to 1.6461 depending on complications. Higher weights mean higher Medicare reimbursement.

What is the ICD-9 equivalent of E27.9?

Under the General Equivalence Mappings, disorder of adrenal gland, unspecified converts to ICD-9-CM 255.9 (adrenal disorder NOS). The mapping is a direct match.

Footnotes

[1] Chronic - a chronic condition code indicates a condition lasting 12 months or longer and its effect on the patient based on one or both of the following criteria:

  • The condition results in the need for ongoing intervention with medical products,treatment, services, and special equipment
  • The condition places limitations on self-care, independent living, and social interactions.