Malignant neoplasm of anus and anal canal (C21)

The ICD-10 codes C21 through C21.8 classify various types of malignant tumors affecting the anus and anal canal. These codes are specifically used to document cancers located in different areas such as the anus, anal canal, cloacogenic zone, and overlapping sites of the rectum and anus.

The section includes codes like C21.0 for unspecified malignant neoplasm of the anus, covering terms such as lymphoma of the anus, adenocarcinoma, and carcinoma of the anus. C21.1 addresses malignant tumors in the anal canal, including primary carcinoma, Paget's disease of the anal canal, and malignant melanoma, providing detailed options for coding cancers specific to this site. C21.2 targets the cloacogenic zone, a distinct area near the anus where cloacogenic carcinoma may arise. Finally, C21.8 codes for cancers involving overlapping regions of the rectum, anus, and anal canal, which may be described as anorectal adenocarcinoma or tumors at the anorectal junction. Recognizing these synonyms and their corresponding ICD-10 codes is essential when coding for anal cancers to ensure precise documentation and treatment planning.

Instructional Notations

Type 2 Excludes

A type 2 excludes note represents "Not included here". An excludes2 note indicates that the condition excluded is not part of the condition represented by the code, but a patient may have both conditions at the same time. When an Excludes2 note appears under a code, it is acceptable to use both the code and the excluded code together, when appropriate.