Other benign neoplasms of connective and other soft tissue (D21) ICD-10-CM
The D21 code range covers other benign neoplasms of connective and other soft tissue with 15 ICD-10-CM diagnosis codes. 12 of them are billable and valid for claim submission in fiscal year 2027, and the category headers group them but cannot themselves be billed.
Includes
This note appears immediately under a three character code title to further define, or give examples of, the content of the category.
- benign neoplasm of blood vessel
- benign neoplasm of bursa
- benign neoplasm of cartilage
- benign neoplasm of fascia
- benign neoplasm of fat
- benign neoplasm of ligament, except uterine
- benign neoplasm of lymphatic channel
- benign neoplasm of muscle
- benign neoplasm of synovia
- benign neoplasm of tendon (sheath)
- benign stromal tumors
Type 1 Excludes
A type 1 excludes note is a pure excludes note. It means "NOT CODED HERE!" An Excludes1 note indicates that the code excluded should never be used at the same time as the code above the Excludes1 note. An Excludes1 is used when two conditions cannot occur together, such as a congenital form versus an acquired form of the same condition.
- benign neoplasm of articular cartilage D16
- benign neoplasm of cartilage of larynx D14.1
- benign neoplasm of cartilage of nose D14.0
- benign neoplasm of connective tissue of breast D24
- benign neoplasm of peripheral nerves and autonomic nervous system D36.1
- benign neoplasm of peritoneum D20.1
- benign neoplasm of retroperitoneum D20.0
- benign neoplasm of uterine ligament, any D28.2
- benign neoplasm of vascular tissue D18
- hemangioma D18.0
- lipomatous neoplasm D17
- lymphangioma D18.1
- uterine leiomyoma D25
Codes in the D21 Range 15 codes · 12 billable
- D21 Other benign neoplasms of connective and other soft tissueNon-billable
- D21.0 Benign neoplasm of connective and other soft tissue of head, face and neck
- D21.1 Benign neoplasm of connective and other soft tissue of upper limb, including shoulderNon-billable
- D21.10 Benign neoplasm of connective and other soft tissue of unspecified upper limb, including shoulder
- D21.11 Benign neoplasm of connective and other soft tissue of right upper limb, including shoulder
- D21.12 Benign neoplasm of connective and other soft tissue of left upper limb, including shoulder
- D21.2 Benign neoplasm of connective and other soft tissue of lower limb, including hipNon-billable
- D21.20 Benign neoplasm of connective and other soft tissue of unspecified lower limb, including hip
- D21.21 Benign neoplasm of connective and other soft tissue of right lower limb, including hip
- D21.22 Benign neoplasm of connective and other soft tissue of left lower limb, including hip
- D21.3 Benign neoplasm of connective and other soft tissue of thorax
- D21.4 Benign neoplasm of connective and other soft tissue of abdomen
- D21.5 Benign neoplasm of connective and other soft tissue of pelvis
- D21.6 Benign neoplasm of connective and other soft tissue of trunk, unspecified
- D21.9 Benign neoplasm of connective and other soft tissue, unspecified
Clinical Terms in This Code Range
Definitions from the National Library of Medicine for conditions coded in the D21 range.
Kimura Disease
A chronic inflammatory disease characterized by benign enlargement of cervical LYMPH NODE and SALIVARY GLANDS with increased levels of IMMUNOGLOBULIN E. Unlike ANGIOLYMPHOID HYPERPLASIA WITH EOSINOPHILIA it involves eosinophil infiltrates in lymph node and salivary glands and mostly found in Asian males.
About the D21 Code Range
These are benign, or noncancerous, growths of connective and other soft tissue. D21 organizes them by where they occur.
The subdivisions distinguish the head, face and neck; upper limbs, including shoulders; lower limbs, including hips; the thorax; the abdomen; and the pelvis. Upper-limb and lower-limb codes further distinguish right, left and unspecified sides. Separate codes identify an unspecified part of the trunk and an unspecified site.
Questions About This Page
How many billable codes are in the D21 range?
Of the 15 codes in this range, 12 are billable and valid for claim submission from October 1, 2026 through September 30, 2027. Category header codes group them but cannot be reported on claims.
What does the D21 range classify?
The range classifies other benign neoplasms of connective and other soft tissue. Each code links to its own reference page with billing status, MS-DRG grouping, coding notes, and clinical information.
Related References
Source: CMS FY 2027 ICD-10-CM Tabular List and order file, effective October 1, 2026 through September 30, 2027.