Neoplasms of unspecified behavior (D49) ICD-10-CM
The D49 code range covers neoplasms of unspecified behavior with 18 ICD-10-CM diagnosis codes. 14 of them are billable and valid for claim submission in fiscal year 2027, and the category headers group them but cannot themselves be billed.
Includes
This note appears immediately under a three character code title to further define, or give examples of, the content of the category.
- 'growth' NOS
- neoplasm NOS
- new growth NOS
- tumor NOS
Type 2 Excludes
A type 2 excludes note represents "Not included here". An excludes2 note indicates that the condition excluded is not part of the condition represented by the code, but a patient may have both conditions at the same time. When an Excludes2 note appears under a code, it is acceptable to use both the code and the excluded code together, when appropriate.
- Category D49 classifies by site neoplasms of unspecified morphology and behavior. The term 'mass', unless otherwise stated, is not to be regarded as a neoplastic growth.
Codes in the D49 Range 18 codes · 14 billable
- D49 Neoplasms of unspecified behaviorNon-billable
- D49.0 Neoplasm of unspecified behavior of digestive system
- D49.1 Neoplasm of unspecified behavior of respiratory system
- D49.2 Neoplasm of unspecified behavior of bone, soft tissue, and skin
- D49.3 Neoplasm of unspecified behavior of breast
- D49.4 Neoplasm of unspecified behavior of bladder
- D49.5 Neoplasm of unspecified behavior of other genitourinary organsNon-billable
- D49.51 Neoplasm of unspecified behavior of kidneyNon-billable
- D49.511 Neoplasm of unspecified behavior of right kidney
- D49.512 Neoplasm of unspecified behavior of left kidney
- D49.519 Neoplasm of unspecified behavior of unspecified kidney
- D49.59 Neoplasm of unspecified behavior of other genitourinary organ
- D49.6 Neoplasm of unspecified behavior of brain
- D49.7 Neoplasm of unspecified behavior of endocrine glands and other parts of nervous system
- D49.8 Neoplasm of unspecified behavior of other specified sitesNon-billable
- D49.81 Neoplasm of unspecified behavior of retina and choroid
- D49.89 Neoplasm of unspecified behavior of other specified sites
- D49.9 Neoplasm of unspecified behavior of unspecified site
Clinical Terms in This Code Range
Definitions from the National Library of Medicine for conditions coded in the D49 range.
Brain Neoplasm|Brain Tumor
A benign or malignant neoplasm that arises from or metastasizes to the brain.
About the D49 Code Range
These codes describe neoplasms, or tumors, whose behavior is unspecified. They are organized by where the neoplasm is located.
Within D49, D49.0 identifies the digestive system, and D49.1 identifies the respiratory system. D49.2 groups bone, soft tissue, and skin. Separate subdivisions identify the breast (D49.3), bladder (D49.4), other genitourinary organs (D49.5), and brain (D49.6). D49.7 groups endocrine glands with other parts of the nervous system. The remaining subdivisions distinguish other specified sites (D49.8) from an unspecified site (D49.9).
Questions About This Page
How many billable codes are in the D49 range?
Of the 18 codes in this range, 14 are billable and valid for claim submission from October 1, 2026 through September 30, 2027. Category header codes group them but cannot be reported on claims.
What does the D49 range classify?
The range classifies neoplasms of unspecified behavior. Each code links to its own reference page with billing status, MS-DRG grouping, coding notes, and clinical information.
Related References
Source: CMS FY 2027 ICD-10-CM Tabular List and order file, effective October 1, 2026 through September 30, 2027.
