Benign neoplasm of other and unspecified endocrine glands (D35) ICD-10-CM
The D35 code range covers benign neoplasm of other and unspecified endocrine glands with 13 ICD-10-CM diagnosis codes. 11 of them are billable and valid for claim submission in fiscal year 2026, and the category headers group them but cannot themselves be billed.
Use Additional Code
The “use additional code” indicates that a secondary code could be used to further specify the patient’s condition. This note is not mandatory and is only used if enough information is available to assign an additional code.
- code to identify any functional activity
Type 1 Excludes
A type 1 excludes note is a pure excludes note. It means "NOT CODED HERE!" An Excludes1 note indicates that the code excluded should never be used at the same time as the code above the Excludes1 note. An Excludes1 is used when two conditions cannot occur together, such as a congenital form versus an acquired form of the same condition.
Codes in the D35 Range 13 codes · 11 billable
- D35 Benign neoplasm of other and unspecified endocrine glandsNon-billable
- D35.0 Benign neoplasm of adrenal glandNon-billable
- D35.00 Benign neoplasm of unspecified adrenal gland
- D35.01 Benign neoplasm of right adrenal gland
- D35.02 Benign neoplasm of left adrenal gland
- D35.1 Benign neoplasm of parathyroid gland
- D35.2 Benign neoplasm of pituitary gland
- D35.3 Benign neoplasm of craniopharyngeal duct
- D35.4 Benign neoplasm of pineal gland
- D35.5 Benign neoplasm of carotid body
- D35.6 Benign neoplasm of aortic body and other paraganglia
- D35.7 Benign neoplasm of other specified endocrine glands
- D35.9 Benign neoplasm of endocrine gland, unspecified
Clinical Terms in This Code Range
Definitions from the National Library of Medicine for conditions coded in the D35 range.
Carotid Artery, Common
The two principal arteries supplying the structures of the head and neck. They ascend in the neck, one on each side, and at the level of the upper border of the thyroid cartilage, each divides into two branches, the external (CAROTID ARTERY, EXTERNAL) and internal (CAROTID ARTERY, INTERNAL) carotid arteries.
Carotid Body Tumor
Benign paraganglioma at the bifurcation of the COMMON CAROTID ARTERIES. It can encroach on the parapharyngeal space and produce dysphagia, pain, and cranial nerve palsies.
Empty Sella Syndrome
A condition when the SELLA TURCICA is not filled with pituitary tissue. The pituitary gland is either compressed, atrophied, or removed. There are two types: (1) primary empty sella is due a defect in the sella diaphragm leading to arachnoid herniation into the sellar space; (2) secondary empty sella is associated with the removal or treatment of PITUITARY NEOPLASMS.
Glomus Jugulare Tumor
A paraganglioma involving the glomus jugulare, a microscopic collection of chemoreceptor tissue in the adventitia of the bulb of the jugular vein. It may cause paralysis of the vocal cords, attacks of dizziness, blackouts, and nystagmus. It is not resectable but radiation therapy is effective. It regresses slowly, but permanent control is regularly achieved. (From Dorland, 27th ed; Stedman, 25th ed; DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, pp1603-4)
Granular Cell Tumor
Unusual tumor affecting any site of the body, but most often encountered in the head and neck. Considerable debate has surrounded the histogenesis of this neoplasm; however, it is considered to be a myoblastoma of, usually, a benign nature. It affects women more often than men. When it develops beneath the epidermis or mucous membrane, it can lead to proliferation of the squamous cells and mimic squamous cell carcinoma.
Multiple Endocrine Neoplasia Type 2a
A form of multiple endocrine neoplasia characterized by the presence of medullary carcinoma (CARCINOMA, MEDULLARY) of the THYROID GLAND, and usually with the co-occurrence of PHEOCHROMOCYTOMA, producing CALCITONIN and ADRENALINE, respectively. Less frequently, it can occur with hyperplasia or adenoma of the PARATHYROID GLANDS. This disease is due to gain-of-function mutations of the MEN2 gene on CHROMOSOME 10 (Locus: 10q11.2), also known as the RET proto-oncogene that encodes a RECEPTOR PROTEIN-TYROSINE KINASE. It is an autosomal dominant inherited disease.
Paraganglioma
A neural crest tumor usually derived from the chromoreceptor tissue of a paraganglion, such as the carotid body, or medulla of the adrenal gland (usually called a chromaffinoma or pheochromocytoma). It is more common in women than in men. (Stedman, 25th ed; from Segen, Dictionary of Modern Medicine, 1992)
Paraganglioma, Extra-Adrenal
A relatively rare, usually benign neoplasm originating in the chemoreceptor tissue of the CAROTID BODY; GLOMUS JUGULARE; GLOMUS TYMPANICUM; AORTIC BODIES; and the female genital tract. It consists histologically of rounded or ovoid hyperchromatic cells that tend to be grouped in an alveolus-like pattern within a scant to moderate amount of fibrous stroma and a few large thin-walled vascular channels. (From Stedman, 27th ed)
PC12 Cells
A CELL LINE derived from a PHEOCHROMOCYTOMA of the rat ADRENAL MEDULLA. PC12 cells stop dividing and undergo terminal differentiation when treated with NERVE GROWTH FACTOR, making the line a useful model system for NERVE CELL differentiation.
Pheochromocytoma
A usually benign, well-encapsulated, lobular, vascular tumor of chromaffin tissue of the ADRENAL MEDULLA or sympathetic paraganglia. The cardinal symptom, reflecting the increased secretion of EPINEPHRINE and NOREPINEPHRINE, is HYPERTENSION, which may be persistent or intermittent. During severe attacks, there may be HEADACHE; SWEATING, palpitation, apprehension, TREMOR; PALLOR or FLUSHING of the face, NAUSEA and VOMITING, pain in the CHEST and ABDOMEN, and paresthesias of the extremities. The incidence of malignancy is as low as 5% but the pathologic distinction between benign and malignant pheochromocytomas is not clear. (Dorland, 27th ed; DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1298)
Prolactinoma
A pituitary adenoma which secretes PROLACTIN, leading to HYPERPROLACTINEMIA. Clinical manifestations include AMENORRHEA; GALACTORRHEA; IMPOTENCE; HEADACHE; visual disturbances; and CEREBROSPINAL FLUID RHINORRHEA.
Sella Turcica
A bony prominence situated on the upper surface of the body of the sphenoid bone. It houses the PITUITARY GLAND.
About the D35 Code Range
The ICD-10 code section D35 covers benign tumors in various endocrine glands, including the adrenal glands, pituitary gland, parathyroid, and other specific or unspecified endocrine sites. These codes are used to classify noncancerous growths in these hormone-producing organs.
This section includes codes such as D35.0 for benign adrenal gland tumors and more detailed codes like D35.00, which encompasses conditions like adrenal adenoma, pheochromocytoma, and paraganglioma. The code D35.1 refers to benign tumors of the parathyroid gland, often called parathyroid adenomas. Pituitary gland benign neoplasms, including prolactinomas and other adenomas, fall under D35.2, with related growths of the craniopharyngeal duct assigned to D35.3. Less common benign tumors of the pineal gland, carotid body, and aortic body paraganglia are coded as D35.4, D35.5, and D35.6, respectively. This section ensures precise coding for benign endocrine tumors, aiding in diagnostics, reporting, and treatment planning using the appropriate ICD-10 code for conditions like adrenal adenoma or pituitary adenoma.
Questions About This Page
How many billable codes are in the D35 range?
Of the 13 codes in this range, 11 are billable and valid for claim submission from October 1, 2025 through September 30, 2026. Category header codes group them but cannot be reported on claims.
What does the D35 range classify?
The range classifies benign neoplasm of other and unspecified endocrine glands. Each code links to its own reference page with billing status, MS-DRG grouping, coding notes, and clinical information.
Related References
Source: CMS FY 2026 ICD-10-CM Tabular List and order file, effective October 1, 2025 through September 30, 2026.
