Malignant neoplasm of peripheral nerves and autonomic nervous system (C47)
The ICD-10 code C47 covers malignant tumors originating in the peripheral nerves and the autonomic nervous system. These codes specify the location of the cancer, such as the head, limbs, thorax, abdomen, pelvis, or unspecified trunk areas, helping to accurately classify these complex nerve tumors.
The section includes detailed subcodes like C47.0 for malignant neoplasms of peripheral nerves in the head, face, and neck, often referred to as malignant peripheral nerve sheath tumors or primary malignant nerve sheath neoplasms of these areas. Codes such as C47.1 and its subsets represent tumors in the upper limbs, while C47.2 and following detail lower limb involvement, including the hip. Other locations are covered by C47.3 to C47.6, identifying thorax, abdomen, pelvis, or trunk nerve malignancies. There are also codes for overlapping sites (C47.8) and unspecified locations (C47.9), which include a wide range of tumor types and synonyms like malignant Triton tumor or ganglioneuroblastoma. This classification helps medical coders and healthcare providers link clinical conditions with precise diagnosis codes for peripheral nerve cancers in various body regions.
Neoplasms (C00–D49)
Malignant neoplasms of mesothelial and soft tissue (C45-C49)
C47 Malignant neoplasm of peripheral nerves and autonomic nervous system
- C47.0 Malignant neoplasm of peripheral nerves of head, face and neck
C47.1 Malignant neoplasm of peripheral nerves of upper limb, including shoulder
- C47.10 Malignant neoplasm of peripheral nerves of unspecified upper limb, including shoulder
- C47.11 Malignant neoplasm of peripheral nerves of right upper limb, including shoulder
- C47.12 Malignant neoplasm of peripheral nerves of left upper limb, including shoulder
C47.2 Malignant neoplasm of peripheral nerves of lower limb, including hip
- C47.20 Malignant neoplasm of peripheral nerves of unspecified lower limb, including hip
- C47.21 Malignant neoplasm of peripheral nerves of right lower limb, including hip
- C47.22 Malignant neoplasm of peripheral nerves of left lower limb, including hip
- C47.3 Malignant neoplasm of peripheral nerves of thorax
- C47.4 Malignant neoplasm of peripheral nerves of abdomen
- C47.5 Malignant neoplasm of peripheral nerves of pelvis
- C47.6 Malignant neoplasm of peripheral nerves of trunk, unspecified
- C47.8 Malignant neoplasm of overlapping sites of peripheral nerves and autonomic nervous system
- C47.9 Malignant neoplasm of peripheral nerves and autonomic nervous system, unspecified
Malignant neoplasm of peripheral nerves and autonomic nervous system (C47)
Instructional Notations
Includes
This note appears immediately under a three character code title to further define, or give examples of, the content of the category.
- malignant neoplasm of sympathetic and parasympathetic nerves and ganglia
Type 1 Excludes
A type 1 excludes note is a pure excludes note. It means "NOT CODED HERE!" An Excludes1 note indicates that the code excluded should never be used at the same time as the code above the Excludes1 note. An Excludes1 is used when two conditions cannot occur together, such as a congenital form versus an acquired form of the same condition.
- Kaposi's sarcoma of soft tissue C46.1
Clinical Terms
The following clinical terms provide additional context, helping users better understand the clinical background and common associations for each diagnosis listed in this section. Including related terms alongside ICD-10-CM codes supports coders, billers, and healthcare professionals in improving accuracy, enhancing documentation, and facilitating research or patient education.
Brachial Plexus
The large network of nerve fibers which distributes the innervation of the upper extremity. The brachial plexus extends from the neck into the axilla. In humans, the nerves of the plexus usually originate from the lower cervical and the first thoracic spinal cord segments (C5-C8 and T1), but variations are not uncommon.
Brachial Plexus Block
A blocking of NEURAL CONDUCTION in the network of nerve fibers innervating the UPPER EXTREMITY.
Brachial Plexus Neuritis
A syndrome associated with inflammation of the BRACHIAL PLEXUS. Clinical features include severe pain in the shoulder region which may be accompanied by MUSCLE WEAKNESS and loss of sensation in the upper extremity. This condition may be associated with VIRUS DISEASES; IMMUNIZATION; SURGERY; heroin use (see HEROIN DEPENDENCE); and other conditions. The term brachial neuralgia generally refers to pain associated with brachial plexus injury. (From Adams et al., Principles of Neurology, 6th ed, pp1355-6)
Brachial Plexus Neuropathies
Diseases of the cervical (and first thoracic) roots, nerve trunks, cords, and peripheral nerve components of the BRACHIAL PLEXUS. Clinical manifestations include regional pain, PARESTHESIA; MUSCLE WEAKNESS, and decreased sensation (HYPESTHESIA) in the upper extremity. These disorders may be associated with trauma (including BIRTH INJURIES); THORACIC OUTLET SYNDROME; NEOPLASMS; NEURITIS; RADIOTHERAPY; and other conditions. (From Adams et al., Principles of Neurology, 6th ed, pp1351-2)
Ganglioneuroblastoma
A moderately malignant neoplasm composed of primitive neuroectodermal cells dispersed in myxomatous or fibrous stroma intermixed with mature ganglion cells. It may undergo transformation into a neuroblastoma. It arises from the sympathetic trunk or less frequently from the adrenal medulla, cerebral cortex, and other locations. Cervical ganglioneuroblastomas may be associated with HORNER SYNDROME and the tumor may occasionally secrete vasoactive intestinal peptide, resulting in chronic diarrhea.
Horner Syndrome
A syndrome associated with defective sympathetic innervation to one side of the face, including the eye. Clinical features include MIOSIS; mild BLEPHAROPTOSIS; and hemifacial ANHIDROSIS (decreased sweating)(see HYPOHIDROSIS). Lesions of the BRAIN STEM; cervical SPINAL CORD; first thoracic nerve root; apex of the LUNG; CAROTID ARTERY; CAVERNOUS SINUS; and apex of the ORBIT may cause this condition. (From Miller et al., Clinical Neuro-Ophthalmology, 4th ed, pp500-11)
Lumbosacral Plexus
The lumbar and sacral plexuses taken together. The fibers of the lumbosacral plexus originate in the lumbar and upper sacral spinal cord (L1 to S3) and innervate the lower extremities.
Sciatic Nerve
A nerve which originates in the lumbar and sacral spinal cord (L4 to S3) and supplies motor and sensory innervation to the lower extremity. The sciatic nerve, which is the main continuation of the sacral plexus, is the largest nerve in the body. It has two major branches, the TIBIAL NERVE and the PERONEAL NERVE.
Sciatic Neuropathy
Disease or damage involving the SCIATIC NERVE, which divides into the PERONEAL NERVE and TIBIAL NERVE (see also PERONEAL NEUROPATHIES and TIBIAL NEUROPATHY). Clinical manifestations may include SCIATICA or pain localized to the hip, PARESIS or PARALYSIS of posterior thigh muscles and muscles innervated by the peroneal and tibial nerves, and sensory loss involving the lateral and posterior thigh, posterior and lateral leg, and sole of the foot. The sciatic nerve may be affected by trauma; ISCHEMIA; COLLAGEN DISEASES; and other conditions. (From Adams et al., Principles of Neurology, 6th ed, p1363)
