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  2. ICD-10-CM Codes List
  3. C00–D49
  4. C73-C75
  5. Malignant neoplasm of adrenal gland (C74)

Malignant neoplasm of adrenal gland (C74)

The ICD-10 code C74 covers malignant neoplasms of the adrenal gland, specifying cancerous tumors in different parts of this gland. These codes are essential for identifying the exact location and type of adrenal gland cancer, whether in the cortex or medulla, and whether it affects the right, left, or an unspecified part.

The code range from C74.0 to C74.92 includes detailed subcategories for cancers of the adrenal cortex and medulla. For example, C74.00 relates specifically to primary adrenal cortical carcinoma, also known as adrenal carcinoma or malignant neoplasm of the adrenal cortex, and details staging from I to IV based on tumor spread. Similarly, C74.10 and its subcodes identify malignant pheochromocytomas, malignant tumors arising from the adrenal medulla. Codes like C74.90 focus on unspecified parts of the adrenal gland and include neuroblastoma, a cancer of early nerve cells. Using these ICD-10 codes accurately helps medical coders and healthcare providers pinpoint the exact adrenal cancer type and location for treatment and reporting.

Clinical Terms

The following clinical terms provide additional context, helping users better understand the clinical background and common associations for each diagnosis listed in this section. Including related terms alongside ICD-10-CM codes supports coders, billers, and healthcare professionals in improving accuracy, enhancing documentation, and facilitating research or patient education.

Esthesioneuroblastoma, Olfactory

A malignant olfactory neuroblastoma arising from the olfactory epithelium of the superior nasal cavity and cribriform plate. It is uncommon (3% of nasal tumors) and rarely is associated with the production of excess hormones (e.g., SIADH, Cushing Syndrome). It has a high propensity for multiple local recurrences and bony metastases. (From Holland et al., Cancer Medicine, 3rd ed, p1245; J Laryngol Otol 1998 Jul;112(7):628-33)

Neuroblastoma

A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51)

Retinoblastoma

A malignant tumor arising from the nuclear layer of the retina that is the most common primary tumor of the eye in children. The tumor tends to occur in early childhood or infancy and may be present at birth. The majority are sporadic, but the condition may be transmitted as an autosomal dominant trait. Histologic features include dense cellularity, small round polygonal cells, and areas of calcification and necrosis. An abnormal pupil reflex (leukokoria); NYSTAGMUS, PATHOLOGIC; STRABISMUS; and visual loss represent common clinical characteristics of this condition. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, p2104)