Neoplasm of uncertain behavior of oral cavity and digestive organs (D37)
Clinical Information
Acalculous Cholecystitis - Inflammation of the GALLBLADDER wall in the absence of GALLSTONES.
Ampulla of Vater - A dilation of the duodenal papilla that is the opening of the juncture of the COMMON BILE DUCT and the MAIN PANCREATIC DUCT, also known as the hepatopancreatic ampulla.
Angiolymphoid Hyperplasia with Eosinophilia - Solitary or multiple benign cutaneous nodules comprised of immature and mature vascular structures intermingled with endothelial cells and a varied infiltrate of eosinophils, histiocytes, lymphocytes, and mast cells.
Ankyloglossia - A severe congenital restriction of TONGUE movement, resulting from fusion or adherence of the tongue to the floor of the mouth. In partial ankyloglossia (tongue-tie) the LINGUAL FRENUM is abnormally short, or is attached too close to the tip of the tongue. OMIM: 106280
Appendiceal Neoplasms - Tumors or cancer of the APPENDIX.
Appendix - A worm-like blind tube extension from the CECUM.
Bariatric Surgery - Surgical procedures aimed at affecting metabolism and producing major WEIGHT REDUCTION in patients with MORBID OBESITY.
Barrett Esophagus - A condition with damage to the lining of the lower ESOPHAGUS resulting from chronic acid reflux (ESOPHAGITIS, REFLUX). Through the process of metaplasia, the squamous cells are replaced by a columnar epithelium with cells resembling those of the INTESTINE or the salmon-pink mucosa of the STOMACH. Barrett's columnar epithelium is a marker for severe reflux and precursor to ADENOCARCINOMA of the esophagus.
Biliary Dyskinesia - A motility disorder characterized by biliary COLIC, absence of GALLSTONES, and an abnormal GALLBLADDER ejection fraction. It is caused by gallbladder dyskinesia and/or SPHINCTER OF ODDI DYSFUNCTION.
Bluetongue - A reovirus infection, chiefly of sheep, characterized by a swollen blue tongue, catarrhal inflammation of upper respiratory and gastrointestinal tracts, and often by inflammation of sensitive laminae of the feet and coronet.
Body Piercing - The perforation of an anatomical region for the wearing of jewelry.
Carcinoma, Pancreatic Ductal - Carcinoma that arises from the PANCREATIC DUCTS. It accounts for the majority of cancers derived from the PANCREAS.
Cholecystitis - Inflammation of the GALLBLADDER; generally caused by impairment of BILE flow, GALLSTONES in the BILIARY TRACT, infections, or other diseases.
Cleft Palate - Congenital fissure of the soft and/or hard palate, due to faulty fusion.
Colon - The segment of LARGE INTESTINE between the CECUM and the RECTUM. It includes the ASCENDING COLON; the TRANSVERSE COLON; the DESCENDING COLON; and the SIGMOID COLON.
Cystic Fibrosis - An autosomal recessive genetic disease of the EXOCRINE GLANDS. It is caused by mutations in the gene encoding the CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR expressed in several organs including the LUNG, the PANCREAS, the BILIARY SYSTEM, and the SWEAT GLANDS. Cystic fibrosis is characterized by epithelial secretory dysfunction associated with ductal obstruction resulting in AIRWAY OBSTRUCTION; chronic RESPIRATORY INFECTIONS; PANCREATIC INSUFFICIENCY; maldigestion; salt depletion; and HEAT PROSTRATION.
Diverticulosis, Stomach - A pathological condition characterized by the presence of a number of GASTRIC DIVERTICULA in the STOMACH.
Diverticulum, Stomach - Saccular, outward protrusion of all or a portion of the wall of the STOMACH.
Duodenal Neoplasms - Tumors or cancer of the DUODENUM.
Duodenum - The shortest and widest portion of the SMALL INTESTINE adjacent to the PYLORUS of the STOMACH. It is named for having the length equal to about the width of 12 fingers.
Electronic Nose - A device used to detect airborne odors, gases, flavors, volatile substances or vapors.
Esophageal Motility Disorders - Disorders affecting the motor function of the UPPER ESOPHAGEAL SPHINCTER; LOWER ESOPHAGEAL SPHINCTER; the ESOPHAGUS body, or a combination of these parts. The failure of the sphincters to maintain a tonic pressure may result in gastric reflux of food and acid into the esophagus (GASTROESOPHAGEAL REFLUX). Other disorders include hypermotility (spastic disorders) and markedly increased amplitude in contraction (nutcracker esophagus).
Esophageal Mucosa - Circular innermost layer of the ESOPHAGUS wall that mediates esophageal PERISTALSIS which pushes ingested food bolus toward the stomach.
Esophageal Neoplasms - Tumors or cancer of the ESOPHAGUS.
Esophagogastric Junction - The area covering the terminal portion of ESOPHAGUS and the beginning of STOMACH at the cardiac orifice.
Esophagus - The muscular membranous segment between the PHARYNX and the STOMACH in the UPPER GASTROINTESTINAL TRACT.
Fasciculation - Involuntary contraction of the muscle fibers innervated by a motor unit. Fasciculations may be visualized as a muscle twitch or dimpling under the skin, but usually do not generate sufficient force to move a limb. They may represent a benign condition or occur as a manifestation of MOTOR NEURON DISEASE or PERIPHERAL NERVOUS SYSTEM DISEASES. (Adams et al., Principles of Neurology, 6th ed, p1294)
Gallbladder - A storage reservoir for BILE secretion. Gallbladder allows the delivery of bile acids at a high concentration and in a controlled manner, via the CYSTIC DUCT to the DUODENUM, for degradation of dietary lipid.
Gallbladder Diseases - Diseases of the GALLBLADDER. They generally involve the impairment of BILE flow, GALLSTONES in the BILIARY TRACT, infections, neoplasms, or other diseases.
Gallbladder Emptying - A process whereby bile is delivered from the gallbladder into the duodenum. The emptying is caused by both contraction of the gallbladder and relaxation of the sphincter mechanism at the choledochal terminus.
Gallbladder Neoplasms - Tumors or cancer of the gallbladder.
Gastric Absorption - Uptake of substances via the stomach.
Gastric Antral Vascular Ectasia - A distinct vascular lesion in the PYLORIC ANTRUM that is characterized by tortuous dilated blood vessels (ectasia) radiating outward from the PYLORUS. The vessel pattern resembles the stripes on the surface of a watermelon. This lesion causes both acute and chronic GASTROINTESTINAL HEMORRHAGE.
Gastric Dilatation - Abnormal distention of the STOMACH due to accumulation of gastric contents that may reach 10 to 15 liters. Gastric dilatation may be the result of GASTRIC OUTLET OBSTRUCTION; ILEUS; GASTROPARESIS; or denervation.
Gastric Fistula - Abnormal passage communicating with the STOMACH.
Gastric Stump - That portion of the stomach remaining after gastric surgery, usually gastrectomy or gastroenterostomy for cancer of the stomach or peptic ulcer. It is a common site of cancer referred to as stump cancer or carcinoma of the gastric stump.
Gastrinoma - A GASTRIN-secreting neuroendocrine tumor of the non-beta ISLET CELLS, the GASTRIN-SECRETING CELLS. This type of tumor is primarily located in the PANCREAS or the DUODENUM. Majority of gastrinomas are malignant. They metastasize to the LIVER; LYMPH NODES; and BONE but rarely elsewhere. The presence of gastrinoma is one of three requirements to be met for identification of ZOLLINGER-ELLISON SYNDROME, which sometimes occurs in families with MULTIPLE ENDOCRINE NEOPLASIA TYPE 1; (MEN 1).
Gastrointestinal Contents - The contents included in all or any segment of the GASTROINTESTINAL TRACT.
Glossitis, Benign Migratory - An idiopathic disorder of the tongue characterized by the loss of filiform papillae leaving reddened areas of circinate macules bound by a white band. The lesions heal, then others erupt.
Hemangioendothelioma - A neoplasm derived from blood vessels, characterized by numerous prominent endothelial cells that occur singly, in aggregates, and as the lining of congeries of vascular tubes or channels. Hemangioendotheliomas are relatively rare and are of intermediate malignancy (between benign hemangiomas and conventional angiosarcomas). They affect men and women about equally and rarely develop in childhood. (From Stedman, 25th ed; Holland et al., Cancer Medicine, 3d ed, p1866)
Hemangioendothelioma, Epithelioid - A tumor of medium-to-large veins, composed of plump-to-spindled endothelial cells that bulge into vascular spaces in a tombstone-like fashion. These tumors are thought to have borderline aggression, where one-third develop local recurrences, but only rarely metastasize. It is unclear whether the epithelioid hemangioendothelioma is truly neoplastic or an exuberant tissue reaction, nor is it clear if this is equivalent to Kimura's disease (see ANGIOLYMPHOID HYPERPLASIA WITH EOSINOPHILIA). (Segen, Dictionary of Modern Medicine, 1992)
Hep G2 Cells - A human liver tumor cell line used to study a variety of liver-specific metabolic functions.
Hepatoblastoma - A malignant neoplasm occurring in young children, primarily in the liver, composed of tissue resembling embryonal or fetal hepatic epithelium, or mixed epithelial and mesenchymal tissues. (Stedman, 25th ed)
Insulin Infusion Systems - Portable or implantable devices for infusion of insulin. Includes open-loop systems which may be patient-operated or controlled by a pre-set program and are designed for constant delivery of small quantities of insulin, increased during food ingestion, and closed-loop systems which deliver quantities of insulin automatically based on an electronic glucose sensor.
Islets of Langerhans - Irregular microscopic structures consisting of cords of endocrine cells that are scattered throughout the PANCREAS among the exocrine acini. Each islet is surrounded by connective tissue fibers and penetrated by a network of capillaries. There are four major cell types. The most abundant beta cells (50-80%) secrete INSULIN. Alpha cells (5-20%) secrete GLUCAGON. PP cells (10-35%) secrete PANCREATIC POLYPEPTIDE. Delta cells (~5%) secrete SOMATOSTATIN.
Jejunal Neoplasms - Tumors or cancer in the JEJUNUM region of the small intestine (INTESTINE, SMALL).
Jejunum - The middle portion of the SMALL INTESTINE, between DUODENUM and ILEUM. It represents about 2/5 of the remaining portion of the small intestine below duodenum.
Medicine, Chinese Traditional - A system of traditional medicine which is based on the beliefs and practices of the Chinese culture.
Necrolytic Migratory Erythema - Recurrent cutaneous manifestation of GLUCAGONOMA characterized by necrolytic polycyclic migratory lesions with scaling borders. It is associated with elevated secretion of GLUCAGON by the tumor. Other conditions with elevated serum glucagon levels such as HEPATIC CIRRHOSIS may also result in similar skin lesions, which are referred to as pseudoglucagonoma syndrome.
Nesidioblastosis - An inherited autosomal recessive syndrome characterized by the disorganized formation of new islets in the PANCREAS and CONGENITAL HYPERINSULINISM. It is due to focal hyperplasia of pancreatic ISLET CELLS budding off from the ductal structures and forming new islets of Langerhans. Mutations in the islet cells involve the potassium channel gene KCNJ11 or the ATP-binding cassette transporter gene ABCC8, both on CHROMOSOME 11.
Oral Frenectomy - Surgical procedures to release or remove abnormally short or tightly attached frenum (e.g., LINGUAL FRENUM or LABIAL FRENUM) associated with a pathological condition (e.g., TONGUE TIE and lip tie).
Oropharyngeal Neoplasms - Tumors or cancer of the OROPHARYNX.
Oropharynx - The middle portion of the pharynx that lies posterior to the mouth, inferior to the SOFT PALATE, and superior to the base of the tongue and EPIGLOTTIS. It has a digestive function as food passes from the mouth into the oropharynx before entering ESOPHAGUS.
Palatal Obturators - Appliances that close a cleft or fissure of the palate.
Palate - The structure that forms the roof of the mouth. It consists of the anterior hard palate (PALATE, HARD) and the posterior soft palate (PALATE, SOFT).
Palate, Hard - The anteriorly located rigid section of the PALATE.
Palate, Soft - A movable fold suspended from the posterior border of the hard palate. The uvula hangs from the middle of the lower border.
Pancreas - A nodular organ in the ABDOMEN that contains a mixture of ENDOCRINE GLANDS and EXOCRINE GLANDS. The small endocrine portion consists of the ISLETS OF LANGERHANS secreting a number of hormones into the blood stream. The large exocrine portion (EXOCRINE PANCREAS) is a compound acinar gland that secretes several digestive enzymes into the pancreatic ductal system that empties into the DUODENUM.
Pancreas Divisum - Anatomic variants in PANCREATIC DUCTS characterized by failure of fusion of the ventral and dorsal endodermal buds. Pancreas divisum results in inadequate or no communication between dorsal and ventral ducts. While most cases are asymptomatic, it may be associated with recurrent PANCREATITIS.
Pancreas Transplantation - The transference of a pancreas from one human or animal to another.
Pancreas, Artificial - Devices for simulating the activity of the pancreas. They can be either electromechanical, consisting of a glucose sensor, computer, and insulin pump or bioartificial, consisting of isolated islets of Langerhans in an artificial membrane.
Pancreas, Exocrine - The major component (about 80%) of the PANCREAS composed of acinar functional units of tubular and spherical cells. The acinar cells synthesize and secrete several digestive enzymes such as TRYPSINOGEN; LIPASE; AMYLASE; and RIBONUCLEASE. Secretion from the exocrine pancreas drains into the pancreatic ductal system and empties into the DUODENUM.
Pancreatic Neoplasms - Tumors or cancer of the PANCREAS. Depending on the types of ISLET CELLS present in the tumors, various hormones can be secreted: GLUCAGON from PANCREATIC ALPHA CELLS; INSULIN from PANCREATIC BETA CELLS; and SOMATOSTATIN from the SOMATOSTATIN-SECRETING CELLS. Most are malignant except the insulin-producing tumors (INSULINOMA).
Pancrelipase - A preparation of hog pancreatic enzymes standardized for lipase content.
Pentastomida - A subclass of CRUSTACEA comprising the tongue worms which are obligatory parasites of reptiles, birds, and mammals including humans.
Pyloric Stenosis - Narrowing of the pyloric canal with varied etiology. A common form is due to muscle hypertrophy (PYLORIC STENOSIS, HYPERTROPHIC) seen in infants.
Pylorus - The region of the STOMACH at the junction with the DUODENUM. It is marked by the thickening of circular muscle layers forming the pyloric sphincter to control the opening and closure of the lumen.
Receptor-Like Protein Tyrosine Phosphatases, Class 3 - A subclass of receptor-like protein tryosine phosphatases that contain a single cytosolic protein tyrosine phosphate domain and multiple extracellular fibronectin III-like domains.
Shwachman-Diamond Syndrome - An inherited syndrome characterized by EXOCRINE PANCREATIC INSUFFICIENCY; hematologic abnormalities (e.g., bone marrow hypoplasia), and skeletal abnormalities (e.g., metaphyseal chondroplasia). GERMLINE MUTATIONS in the SBDS gene are associated with Shwachman-Diamond Syndrome.
Somatostatinoma - A SOMATOSTATIN-secreting tumor derived from the pancreatic delta cells (SOMATOSTATIN-SECRETING CELLS). It is also found in the INTESTINE. Somatostatinomas are associated with DIABETES MELLITUS; CHOLELITHIASIS; STEATORRHEA; and HYPOCHLORHYDRIA. The majority of somatostatinomas have the potential for METASTASIS.
Stomach - An organ of digestion situated in the left upper quadrant of the abdomen between the termination of the ESOPHAGUS and the beginning of the DUODENUM.
Stomach Diseases - Pathological processes involving the STOMACH.
Stomach Neoplasms - Tumors or cancer of the STOMACH.
Stomach Rupture - Bursting of the STOMACH.
Stomach Ulcer - Ulceration of the GASTRIC MUCOSA due to contact with GASTRIC JUICE. It is often associated with HELICOBACTER PYLORI infection or consumption of nonsteroidal anti-inflammatory drugs (NSAIDS).
Stomach Volvulus - Twisting of the STOMACH that may result in gastric ISCHEMIA and GASTRIC OUTLET OBSTRUCTION. It is often associated with DIAPHRAGMATIC HERNIA.
Stomach, Avian - A component of the digestive system of birds which consists of the GIZZARD and PROVENTRICULUS.
Stomach, Ruminant - A component of the DIGESTIVE SYSTEM of RUMINANTS which consists of the ABOMASUM; OMASUM; RETICULUM; and RUMEN.
Submandibular Gland - One of two salivary glands in the neck, located in the space bound by the two bellies of the digastric muscle and the angle of the mandible. It discharges through the submandibular duct. The secretory units are predominantly serous although a few mucous alveoli, some with serous demilunes, occur. (Stedman, 25th ed)
Submandibular Gland Diseases - Diseases involving the SUBMANDIBULAR GLAND.
Submandibular Gland Neoplasms - New abnormal growth of tissue in the SUBMANDIBULAR GLAND.
Tongue - A muscular organ in the mouth that is covered with pink tissue called mucosa, tiny bumps called papillae, and thousands of taste buds. The tongue is anchored to the mouth and is vital for chewing, swallowing, and for speech.
Tongue Diseases - Diseases involving the TONGUE.
Tongue Habits - Acquired responses regularly manifested by tongue movement or positioning.
Tongue Neoplasms - Tumors or cancer of the TONGUE.
Tongue, Fissured - The occurrence of of breaks or slits in the tissue of the dorsal surface of the TONGUE.
Tongue, Hairy - A benign condition of the tongue characterized by hypertrophy of the filiform papillae that give the dorsum of the tongue a furry appearance. The color of the elongated papillae varies from yellowish white to brown or black, depending upon staining by substances such as tobacco, food, or drugs. (Dorland, 27th ed)
Instructional Notations
Type 1 Excludes
A type 1 excludes note is a pure excludes note. It means "NOT CODED HERE!" An Excludes1 note indicates that the code excluded should never be used at the same time as the code above the Excludes1 note. An Excludes1 is used when two conditions cannot occur together, such as a congenital form versus an acquired form of the same condition.
- stromal tumors of uncertain behavior of digestive system D48.1
Neoplasms (C00–D49)
Neoplasms of uncertain behavior, polycythemia vera and myelodysplastic syndromes (D37-D48)
D37 Neoplasm of uncertain behavior of oral cavity and digestive organs
D37.0 Neoplasm of uncertain behavior of lip, oral cavity and pharynx
- D37.01 Neoplasm of uncertain behavior of lip
- D37.02 Neoplasm of uncertain behavior of tongue
D37.03 Neoplasm of uncertain behavior of the major salivary glands
- D37.030 Neoplasm of uncertain behavior of the parotid salivary glands
- D37.031 Neoplasm of uncertain behavior of the sublingual salivary glands
- D37.032 Neoplasm of uncertain behavior of the submandibular salivary glands
- D37.039 Neoplasm of uncertain behavior of the major salivary glands, unspecified
- D37.04 Neoplasm of uncertain behavior of the minor salivary glands
- D37.05 Neoplasm of uncertain behavior of pharynx
- D37.09 Neoplasm of uncertain behavior of other specified sites of the oral cavity
- D37.1 Neoplasm of uncertain behavior of stomach
- D37.2 Neoplasm of uncertain behavior of small intestine
- D37.3 Neoplasm of uncertain behavior of appendix
- D37.4 Neoplasm of uncertain behavior of colon
- D37.5 Neoplasm of uncertain behavior of rectum
- D37.6 Neoplasm of uncertain behavior of liver, gallbladder and bile ducts
- D37.8 Neoplasm of uncertain behavior of other specified digestive organs
- D37.9 Neoplasm of uncertain behavior of digestive organ, unspecified
Neoplasm of uncertain behavior of oral cavity and digestive organs (D37)