Malignant neoplasms of mesothelial and soft tissue (C45-C49) ICD-10-CM
The C45–C49 section covers malignant neoplasms of mesothelial and soft tissue with 63 ICD-10-CM diagnosis codes, of which 52 are billable in fiscal year 2027. The section is organized into the 5 code ranges listed below.
Code Ranges in This Section 5 ranges · 63 codes
The info icon previews the code ranges inside each row and its instructional notations from the official Tabular List.
About the C45–C49 Code Range
These cancers include mesothelioma and Kaposi's sarcoma, plus tumors of nerves, the peritoneum or retroperitoneum, and connective or soft tissue.
C45 groups mesothelioma by site, including the pleura, peritoneum and pericardium. C46 groups Kaposi's sarcoma by site, including skin, soft tissue, lymph nodes and lung.
C47 covers cancers of peripheral nerves and the autonomic nervous system, with subdivisions by body area. C48 separates cancers of the retroperitoneum from those of the peritoneum. C49 groups other connective and soft tissue cancers by body area and includes C49.A for gastrointestinal stromal tumor.
Questions About This Page
How many codes are in the C45-C49 range?
The C45-C49 range contains 63 ICD-10-CM diagnosis codes in FY 2027. 52 of them are billable, and the rest are category headers that organize the section.
What conditions does C45-C49 cover?
The range covers malignant neoplasms of mesothelial and soft tissue. The code ranges listed above break it into groups of related conditions, and each one links to its own page with the full code list.
Related References
Source: CMS FY 2027 ICD-10-CM Tabular List and order file, effective October 1, 2026 through September 30, 2027.
