Malignant neoplasms of mesothelial and soft tissue (C45-C49)

ICD-10 codes C45-C49 cover malignant neoplasms arising from mesothelial tissue, soft tissues, peripheral nerves, and connective tissues. These codes specifically identify different types of cancers such as mesothelioma, Kaposi's sarcoma, malignant peripheral nerve tumors, retroperitoneal cancers, and various soft tissue sarcomas.

The range includes mesothelioma (C45), with detailed codes for pleura (C45.0), peritoneum (C45.1), pericardium (C45.2), and other less common sites, providing precise classification for tumors of the mesothelial lining. Kaposi's sarcoma (C46) is categorized by affected body regions like skin, soft tissue, lung, and gastrointestinal sites, helping in identifying this vascular tumor associated with immunodeficiency. Malignant neoplasms of peripheral nerves and the autonomic nervous system (C47) are further divided by anatomical location (head, limbs, thorax, abdomen, pelvis, and trunk) and specify right, left, or unspecified limbs for accuracy. The codes also include malignant retroperitoneal and peritoneal tumors (C48), distinguishing specific peritoneal sites and retroperitoneal regions. Additionally, malignant neoplasms of other connective and soft tissues (C49) focus on tumors involving soft tissue and connective tissue across body regions such as head, limbs, trunk, and pelvis. This section also includes gastrointestinal stromal tumors (C49.A), which are important in identifying primary tumors of the digestive tract's connective tissues. These codes assist coders and clinicians in precisely documenting distinct malignant soft tissue tumors for proper diagnosis, treatment planning, and research.

  • Neoplasms (C00–D49)

    • Malignant neoplasms of mesothelial and soft tissue (C45-C49)

        • Kaposi's sarcoma (C46)

        • C46 Kaposi's sarcoma
        • C46.0 Kaposi's sarcoma of skin
        • C46.1 Kaposi's sarcoma of soft tissue
        • C46.2 Kaposi's sarcoma of palate
        • C46.3 Kaposi's sarcoma of lymph nodes
        • C46.4 Kaposi's sarcoma of gastrointestinal sites
        • C46.5 Kaposi's sarcoma of lung
        • C46.50 Kaposi's sarcoma of unspecified lung
        • C46.51 Kaposi's sarcoma of right lung
        • C46.52 Kaposi's sarcoma of left lung
        • C46.7 Kaposi's sarcoma of other sites
        • C46.9 Kaposi's sarcoma, unspecified
        • Malignant neoplasm of peripheral nerves and autonomic nervous system (C47)

        • C47 Malignant neoplasm of peripheral nerves and autonomic nervous system
        • C47.0 Malignant neoplasm of peripheral nerves of head, face and neck
        • C47.1 Malignant neoplasm of peripheral nerves of upper limb, including shoulder
        • C47.10 Malignant neoplasm of peripheral nerves of unspecified upper limb, including shoulder
        • C47.11 Malignant neoplasm of peripheral nerves of right upper limb, including shoulder
        • C47.12 Malignant neoplasm of peripheral nerves of left upper limb, including shoulder
        • C47.2 Malignant neoplasm of peripheral nerves of lower limb, including hip
        • C47.20 Malignant neoplasm of peripheral nerves of unspecified lower limb, including hip
        • C47.21 Malignant neoplasm of peripheral nerves of right lower limb, including hip
        • C47.22 Malignant neoplasm of peripheral nerves of left lower limb, including hip
        • C47.3 Malignant neoplasm of peripheral nerves of thorax
        • C47.4 Malignant neoplasm of peripheral nerves of abdomen
        • C47.5 Malignant neoplasm of peripheral nerves of pelvis
        • C47.6 Malignant neoplasm of peripheral nerves of trunk, unspecified
        • C47.8 Malignant neoplasm of overlapping sites of peripheral nerves and autonomic nervous system
        • C47.9 Malignant neoplasm of peripheral nerves and autonomic nervous system, unspecified
        • Malignant neoplasm of other connective and soft tissue (C49)

        • C49 Malignant neoplasm of other connective and soft tissue
        • C49.0 Malignant neoplasm of connective and soft tissue of head, face and neck
        • C49.1 Malignant neoplasm of connective and soft tissue of upper limb, including shoulder
        • C49.10 Malignant neoplasm of connective and soft tissue of unspecified upper limb, including shoulder
        • C49.11 Malignant neoplasm of connective and soft tissue of right upper limb, including shoulder
        • C49.12 Malignant neoplasm of connective and soft tissue of left upper limb, including shoulder
        • C49.2 Malignant neoplasm of connective and soft tissue of lower limb, including hip
        • C49.20 Malignant neoplasm of connective and soft tissue of unspecified lower limb, including hip
        • C49.21 Malignant neoplasm of connective and soft tissue of right lower limb, including hip
        • C49.22 Malignant neoplasm of connective and soft tissue of left lower limb, including hip
        • C49.3 Malignant neoplasm of connective and soft tissue of thorax
        • C49.4 Malignant neoplasm of connective and soft tissue of abdomen
        • C49.5 Malignant neoplasm of connective and soft tissue of pelvis
        • C49.6 Malignant neoplasm of connective and soft tissue of trunk, unspecified
        • C49.8 Malignant neoplasm of overlapping sites of connective and soft tissue
        • C49.9 Malignant neoplasm of connective and soft tissue, unspecified
        • C49.A Gastrointestinal stromal tumor
        • C49.A0 Gastrointestinal stromal tumor, unspecified site
        • C49.A1 Gastrointestinal stromal tumor of esophagus
        • C49.A2 Gastrointestinal stromal tumor of stomach
        • C49.A3 Gastrointestinal stromal tumor of small intestine
        • C49.A4 Gastrointestinal stromal tumor of large intestine
        • C49.A5 Gastrointestinal stromal tumor of rectum
        • C49.A9 Gastrointestinal stromal tumor of other sites