Neoplasm of uncertain behavior of other and unspecified sites (D48) ICD-10-CM
The D48 code range covers neoplasm of uncertain behavior of other and unspecified sites with 25 ICD-10-CM diagnosis codes. 21 of them are billable and valid for claim submission in fiscal year 2027, and the category headers group them but cannot themselves be billed.
Type 1 Excludes
A type 1 excludes note is a pure excludes note. It means "NOT CODED HERE!" An Excludes1 note indicates that the code excluded should never be used at the same time as the code above the Excludes1 note. An Excludes1 is used when two conditions cannot occur together, such as a congenital form versus an acquired form of the same condition.
- neurofibromatosis nonmalignant Q85.0
Codes in the D48 Range 25 codes · 21 billable
- D48 Neoplasm of uncertain behavior of other and unspecified sitesNon-billable
- D48.0 Neoplasm of uncertain behavior of bone and articular cartilage
- D48.1 Neoplasm of uncertain behavior of connective and other soft tissueNon-billable
- D48.11 Desmoid tumorNon-billable
- D48.110 Desmoid tumor of head and neck
- D48.111 Desmoid tumor of chest wall
- D48.112 Desmoid tumor, intrathoracic
- D48.113 Desmoid tumor of abdominal wall
- D48.114 Desmoid tumor, intraabdominal
- D48.115 Desmoid tumor of upper extremity and shoulder girdle
- D48.116 Desmoid tumor of lower extremity and pelvic girdle
- D48.117 Desmoid tumor of back
- D48.118 Desmoid tumor of other site
- D48.119 Desmoid tumor of unspecified site
- D48.19 Other specified neoplasm of uncertain behavior of connective and other soft tissue
- D48.2 Neoplasm of uncertain behavior of peripheral nerves and autonomic nervous system
- D48.3 Neoplasm of uncertain behavior of retroperitoneum
- D48.4 Neoplasm of uncertain behavior of peritoneum
- D48.5 Neoplasm of uncertain behavior of skin
- D48.6 Neoplasm of uncertain behavior of breastNon-billable
- D48.60 Neoplasm of uncertain behavior of unspecified breast
- D48.61 Neoplasm of uncertain behavior of right breast
- D48.62 Neoplasm of uncertain behavior of left breast
- D48.7 Neoplasm of uncertain behavior of other specified sites
- D48.9 Neoplasm of uncertain behavior, unspecified
Clinical Terms in This Code Range
Definitions from the National Library of Medicine for conditions coded in the D48 range.
Chest Wall Fibromatosis
An extraabdominal fibromatosis arising from the soft tissue of the chest wall. It is characterized by the presence of elongated spindle-shaped fibroblasts, collagenous stroma formation, and an infiltrative growth pattern.
Desmoid Tumors
Locally aggressive tumors that form in the connective tissues of body with no known potential for metastasis. However, they are characterized by an infiltrative growth pattern, allowing invasion into nearby tissues and organs, particularly evident in patients with FAMILIAL ADENOMATOUS POLYPOSIS.
Myofibromatosis
A condition characterized by multiple formations of myofibromas (LEIOMYOMA).
Phyllodes Tumor
A type of connective tissue neoplasm typically arising from intralobular stroma of the breast. It is characterized by the rapid enlargement of an asymmetric firm mobile mass. Histologically, its leaf-like stromal clefts are lined by EPITHELIAL CELLS. Rare phyllodes tumor of the prostate is also known.
About the D48 Code Range
These growths have uncertain behavior and occur in sites such as bone, soft tissue, skin, and breast.
D48 is organized mainly by body site, with separate subdivisions for bone and joint cartilage, soft tissue, nerves, abdominal tissues, skin, and breast. Within soft tissue, D48.11 groups desmoid tumors by location, including the head and neck, chest, abdomen, limbs, and back. Breast subdivisions distinguish the right breast, left breast, and an unspecified breast. D48.7 identifies other specified sites, while D48.9 leaves the site unspecified.
Questions About This Page
How many billable codes are in the D48 range?
Of the 25 codes in this range, 21 are billable and valid for claim submission from October 1, 2026 through September 30, 2027. Category header codes group them but cannot be reported on claims.
What does the D48 range classify?
The range classifies neoplasm of uncertain behavior of other and unspecified sites. Each code links to its own reference page with billing status, MS-DRG grouping, coding notes, and clinical information.
Related References
Source: CMS FY 2027 ICD-10-CM Tabular List and order file, effective October 1, 2026 through September 30, 2027.
