ICD-10-CM Tabular Index · Chapter 2 · FY 2026 D01

Carcinoma in situ of other and unspecified digestive organs (D01) ICD-10-CM

The D01 code range covers carcinoma in situ of other and unspecified digestive organs with 11 ICD-10-CM diagnosis codes. 9 of them are billable and valid for claim submission in fiscal year 2026, and the category headers group them but cannot themselves be billed.

✓ Built from the official CMS FY 2026 datasetEffective Oct 1, 2025 – Sep 30, 2026
11
Diagnosis Codes
9
Billable Codes
D01
Code Range
D00–D09
Parent Section

Type 1 Excludes

A type 1 excludes note is a pure excludes note. It means "NOT CODED HERE!" An Excludes1 note indicates that the code excluded should never be used at the same time as the code above the Excludes1 note. An Excludes1 is used when two conditions cannot occur together, such as a congenital form versus an acquired form of the same condition.

ICD-10-CM

Codes in the D01 Range 11 codes · 9 billable

11 of 11 shown
  • D01 Carcinoma in situ of other and unspecified digestive organsNon-billable
  • D01.0 Carcinoma in situ of colon
  • D01.1 Carcinoma in situ of rectosigmoid junction
  • D01.2 Carcinoma in situ of rectum
  • D01.3 Carcinoma in situ of anus and anal canal
  • D01.4 Carcinoma in situ of other and unspecified parts of intestineNon-billable
  • D01.40 Carcinoma in situ of unspecified part of intestine
  • D01.49 Carcinoma in situ of other parts of intestine
  • D01.5 Carcinoma in situ of liver, gallbladder and bile ducts
  • D01.7 Carcinoma in situ of other specified digestive organs
  • D01.9 Carcinoma in situ of digestive organ, unspecified

Clinical Terms in This Code Range

Definitions from the National Library of Medicine for conditions coded in the D01 range.

Acalculous Cholecystitis

Inflammation of the GALLBLADDER wall in the absence of GALLSTONES.

Ampulla of Vater

A dilation of the duodenal papilla that is the opening of the juncture of the COMMON BILE DUCT and the MAIN PANCREATIC DUCT, also known as the hepatopancreatic ampulla.

Appendiceal Neoplasms

Tumors or cancer of the APPENDIX.

Appendix

A worm-like blind tube extension from the CECUM.

Biliary Dyskinesia

A motility disorder characterized by biliary COLIC, absence of GALLSTONES, and an abnormal GALLBLADDER ejection fraction. It is caused by gallbladder dyskinesia and/or SPHINCTER OF ODDI DYSFUNCTION.

Carcinoma, Pancreatic Ductal

Carcinoma that arises from the PANCREATIC DUCTS. It accounts for the majority of cancers derived from the PANCREAS.

Cholecystitis

Inflammation of the GALLBLADDER; generally caused by impairment of BILE flow, GALLSTONES in the BILIARY TRACT, infections, or other diseases.

Colon

The segment of LARGE INTESTINE between the CECUM and the RECTUM. It includes the ASCENDING COLON; the TRANSVERSE COLON; the DESCENDING COLON; and the SIGMOID COLON.

Cystic Fibrosis

An autosomal recessive genetic disease of the EXOCRINE GLANDS. It is caused by mutations in the gene encoding the CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR expressed in several organs including the LUNG, the PANCREAS, the BILIARY SYSTEM, and the SWEAT GLANDS. Cystic fibrosis is characterized by epithelial secretory dysfunction associated with ductal obstruction resulting in AIRWAY OBSTRUCTION; chronic RESPIRATORY INFECTIONS; PANCREATIC INSUFFICIENCY; maldigestion; salt depletion; and HEAT PROSTRATION.

Duodenal Neoplasms

Tumors or cancer of the DUODENUM.

Duodenum

The shortest and widest portion of the SMALL INTESTINE adjacent to the PYLORUS of the STOMACH. It is named for having the length equal to about the width of 12 fingers.

Gallbladder

A storage reservoir for BILE secretion. Gallbladder allows the delivery of bile acids at a high concentration and in a controlled manner, via the CYSTIC DUCT to the DUODENUM, for degradation of dietary lipid.

Gallbladder Diseases

Diseases of the GALLBLADDER. They generally involve the impairment of BILE flow, GALLSTONES in the BILIARY TRACT, infections, neoplasms, or other diseases.

Gallbladder Emptying

A process whereby bile is delivered from the gallbladder into the duodenum. The emptying is caused by both contraction of the gallbladder and relaxation of the sphincter mechanism at the choledochal terminus.

Gallbladder Neoplasms

Tumors or cancer of the gallbladder.

Hep G2 Cells

A human liver tumor cell line used to study a variety of liver-specific metabolic functions.

Hepatoblastoma

A malignant neoplasm occurring in young children, primarily in the liver, composed of tissue resembling embryonal or fetal hepatic epithelium, or mixed epithelial and mesenchymal tissues. (Stedman, 25th ed)

Insulin Infusion Systems

Portable or implantable devices for infusion of insulin. Includes open-loop systems which may be patient-operated or controlled by a pre-set program and are designed for constant delivery of small quantities of insulin, increased during food ingestion, and closed-loop systems which deliver quantities of insulin automatically based on an electronic glucose sensor.

Islets of Langerhans

Irregular microscopic structures consisting of cords of endocrine cells that are scattered throughout the PANCREAS among the exocrine acini. Each islet is surrounded by connective tissue fibers and penetrated by a network of capillaries. There are four major cell types. The most abundant beta cells (50-80%) secrete INSULIN. Alpha cells (5-20%) secrete GLUCAGON. PP cells (10-35%) secrete PANCREATIC POLYPEPTIDE. Delta cells (~5%) secrete SOMATOSTATIN.

Jejunal Neoplasms

Tumors or cancer in the JEJUNUM region of the small intestine (INTESTINE, SMALL).

Jejunum

The middle portion of the SMALL INTESTINE, between DUODENUM and ILEUM. It represents about 2/5 of the remaining portion of the small intestine below duodenum.

Nesidioblastosis

An inherited autosomal recessive syndrome characterized by the disorganized formation of new islets in the PANCREAS and CONGENITAL HYPERINSULINISM. It is due to focal hyperplasia of pancreatic ISLET CELLS budding off from the ductal structures and forming new islets of Langerhans. Mutations in the islet cells involve the potassium channel gene KCNJ11 or the ATP-binding cassette transporter gene ABCC8, both on CHROMOSOME 11.

Pancreas

A nodular organ in the ABDOMEN that contains a mixture of ENDOCRINE GLANDS and EXOCRINE GLANDS. The small endocrine portion consists of the ISLETS OF LANGERHANS secreting a number of hormones into the blood stream. The large exocrine portion (EXOCRINE PANCREAS) is a compound acinar gland that secretes several digestive enzymes into the pancreatic ductal system that empties into the DUODENUM.

Pancreas Divisum

Anatomic variants in PANCREATIC DUCTS characterized by failure of fusion of the ventral and dorsal endodermal buds. Pancreas divisum results in inadequate or no communication between dorsal and ventral ducts. While most cases are asymptomatic, it may be associated with recurrent PANCREATITIS.

Pancreas Transplantation

The transference of a pancreas from one human or animal to another.

Pancreas, Artificial

Devices for simulating the activity of the pancreas. They can be either electromechanical, consisting of a glucose sensor, computer, and insulin pump or bioartificial, consisting of isolated islets of Langerhans in an artificial membrane.

Pancreas, Exocrine

The major component (about 80%) of the PANCREAS composed of acinar functional units of tubular and spherical cells. The acinar cells synthesize and secrete several digestive enzymes such as TRYPSINOGEN; LIPASE; AMYLASE; and RIBONUCLEASE. Secretion from the exocrine pancreas drains into the pancreatic ductal system and empties into the DUODENUM.

Pancreatic Neoplasms

Tumors or cancer of the PANCREAS. Depending on the types of ISLET CELLS present in the tumors, various hormones can be secreted: GLUCAGON from PANCREATIC ALPHA CELLS; INSULIN from PANCREATIC BETA CELLS; and SOMATOSTATIN from the SOMATOSTATIN-SECRETING CELLS. Most are malignant except the insulin-producing tumors (INSULINOMA).

Pancrelipase

A preparation of hog pancreatic enzymes standardized for lipase content.

Shwachman-Diamond Syndrome

An inherited syndrome characterized by EXOCRINE PANCREATIC INSUFFICIENCY; hematologic abnormalities (e.g., bone marrow hypoplasia), and skeletal abnormalities (e.g., metaphyseal chondroplasia). GERMLINE MUTATIONS in the SBDS gene are associated with Shwachman-Diamond Syndrome.

About the D01 Code Range

ICD-10 code section D01 is used to classify carcinoma in situ found in various parts of the digestive organs before it has invaded deeper tissues. This includes specific locations such as the colon, rectum, anus, intestine, liver, gallbladder, bile ducts, pancreas, and other digestive sites.

This section helps accurately pinpoint and document early-stage, non-invasive cancers in the digestive tract. For example, D01.0 covers carcinoma in situ of the colon, which includes terms like "neoplasm of hepatic flexure of colon" or "carcinoma in situ of sigmoid colon." Codes like D01.3 correspond to carcinoma in situ of the anus and anal canal, capturing conditions also called "anal intraepithelial neoplasia (AIN III)" or "bowenoid papulosis." Similarly, D01.5 addresses carcinoma in situ of the liver, gallbladder, and bile ducts, encompassing high-grade intraepithelial neoplasia and carcinoma in situ of bile ducts or gallbladder. These specific ICD-10 codes allow healthcare providers and coders to identify and report these localized precancerous conditions precisely, which is essential for early diagnosis and treatment planning. Using these codes ensures clear communication about the cancer’s exact location and stage within the digestive system.

Questions About This Page

How many billable codes are in the D01 range?

Of the 11 codes in this range, 9 are billable and valid for claim submission from October 1, 2025 through September 30, 2026. Category header codes group them but cannot be reported on claims.

What does the D01 range classify?

The range classifies carcinoma in situ of other and unspecified digestive organs. Each code links to its own reference page with billing status, MS-DRG grouping, coding notes, and clinical information.

Related References

Source: CMS FY 2026 ICD-10-CM Tabular List and order file, effective October 1, 2025 through September 30, 2026.