Myelodysplastic syndromes (D46)

ICD-10 code D46 covers a group of disorders called myelodysplastic syndromes (MDS), which involve abnormal blood cell production in the bone marrow. These codes specify different types and features of MDS used to classify the condition precisely for diagnosis and treatment planning.

The detailed codes under D46 range from refractory anemia without ring sideroblasts (D46.0) to refractory anemia with ring sideroblasts (D46.1), which is often referred to by related terms like “X chromosome-linked sideroblastic anemia.” There are also codes for refractory anemia with excess blasts (D46.2 series) describing severity levels, and other subtypes such as refractory cytopenia with multilineage dysplasia (D46.A) and MDS associated with specific chromosomal abnormalities like isolated del(5q) (D46.C). The code D46.9 denotes unspecified myelodysplastic syndrome, encompassing therapy-related and congenital forms. This classification helps medical coders select the correct ICD-10 code for the patient’s precise myelodysplastic diagnosis, ensuring clinical clarity and appropriate healthcare management.

D46 - Myelodysplastic syndromes
D46.2 - Refractory anemia with excess of blasts [RAEB]

Filter diagnosis codes list:

Neoplasms (C00–D49)
- Neoplasms of uncertain behavior, polycythemia vera and myelodysplastic syndromes (D37-D48)
  - - D46 Myelodysplastic syndromes
    - D46.0 Refractory anemia without ring sideroblasts, so stated
    - D46.1 Refractory anemia with ring sideroblasts
    - D46.2 Refractory anemia with excess of blasts [RAEB]
    - D46.20 Refractory anemia with excess of blasts, unspecified
    - D46.21 Refractory anemia with excess of blasts 1
    - D46.22 Refractory anemia with excess of blasts 2
    - D46.4 Refractory anemia, unspecified
    - D46.9 Myelodysplastic syndrome, unspecified
    - D46.A Refractory cytopenia with multilineage dysplasia
    - D46.B Refractory cytopenia with multilineage dysplasia and ring sideroblasts
    - D46.C Myelodysplastic syndrome with isolated del(5q) chromosomal abnormality
    - D46.Z Other myelodysplastic syndromes

Instructional Notations

Use Additional Code

The “use additional code” indicates that a secondary code could be used to further specify the patient’s condition. This note is not mandatory and is only used if enough information is available to assign an additional code.

code for adverse effect, if applicable, to identify drug T36 T50

Type 2 Excludes

A type 2 excludes note represents "Not included here". An excludes2 note indicates that the condition excluded is not part of the condition represented by the code, but a patient may have both conditions at the same time. When an Excludes2 note appears under a code, it is acceptable to use both the code and the excluded code together, when appropriate.

drug-induced aplastic anemia D61.1

Clinical Terms

The following clinical terms provide additional context, helping users better understand the clinical background and common associations for each diagnosis listed in this section. Including related terms alongside ICD-10-CM codes supports coders, billers, and healthcare professionals in improving accuracy, enhancing documentation, and facilitating research or patient education.