2026 ICD-10-CM Diagnosis Code E25.8Other adrenogenital disorders

ICD-10-CM Codes›E00–E89›E20-E35›E25

ICD-10-CM E25.8
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

E25.8 is a billable ICD-10-CM diagnosis code for other adrenogenital disorders. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 643 through 645. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Other specified and unspecified endocrine disorders.

Code Identity

ICD-10-CM Code
E25.8
Billable Status
Yes — Valid for Submission
Code Describes
Other adrenogenital disorders
Short Description
Other adrenogenital disorders
Same as the full description in the CMS dataset.
Parent Code
E25
Adrenogenital disorders

Code Classification

ChapterE00–E89Endocrine, nutritional and metabolic diseases
SectionE20-E35Disorders of other endocrine glands
CategoryE25Adrenogenital disorders
This CodeE25.8Other adrenogenital disorders

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Achard-Thiers syndrome
  • Disorder of androgen receptor
  • Disorder of sexual differentiation
  • Drug-induced adrenogenital disorder
  • Female pseudopuberty
  • Female puberty disorder
  • Feminization-adrenogenital syndrome
  • Gonadotropin independent precocious puberty
  • Iatrogenic adrenogenital disorder
  • Idiopathic adrenogenital disorder
  • Isosexual precocious pseudopuberty
  • Masculinized female
  • Maternal virilization due to placental aromatase deficiency
  • Precocious female puberty
  • Pseudohermaphrodite, male with adrenocortical disorder
  • Pseudo-puberty - feminization
  • Pseudo-puberty - virilization
  • Undervirilization
  • Virilization of female due to SOX9 gene duplication
  • Virilization of female due to SRY gene translocation
  • Virilized female due to gestational hyperandrogenism
  • Virilizing syndrome of adrenal origin

Tabular List NotesGuidance

Coding notes and annotation back-references applicable to this code.

Inclusion Terms

  • Idiopathic adrenogenital disorder

Use Additional Code

  • code for adverse effect, if applicable, to identify drug T36 T50

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Adrenogenital syndrome
      • acquired
    • Disorder(of)
      • adrenogenital
        • drug-induced
    • Disorder(of)
      • adrenogenital
        • iatrogenic
    • Disorder(of)
      • adrenogenital
        • idiopathic
    • Pseudohermaphroditism
      • adrenal
    • Pseudohermaphroditism
      • female
        • with adrenocortical disorder
    • Pseudohermaphroditism
      • male
        • with
          • adrenocortical disorder
    • Pseudohermaphroditism
      • male
        • adrenal
    • Pseudopuberty, precocious
      • female heterosexual
    • Pseudopuberty, precocious
      • male isosexual
    • Puberty(development state)
      • premature
        • due to
          • adrenal cortical hyperfunction

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR END015
Other specified and unspecified endocrine disorders
Default principal diagnosis: inpatient Yes · outpatient Yes

Patient EducationClinical

Adrenal Gland Disorders

Your adrenal glands are two small organs that sit on top of each kidney. The adrenal glands make different types of hormones you need to stay alive and healthy. Hormones are chemicals that travel in your bloodstream and control how different parts of your body work.

The full article covers:

  • What are adrenal glands?
  • What are adrenal gland disorders?
  • What causes adrenal gland disorders?
  • How are adrenal gland disorders diagnosed?
  • What are the treatments for adrenal gland disorders?

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert E25.8 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
255.2 Adrenogenital disorders
Approximate The match is approximate rather than exact.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About E25.8Overview

Is E25.8 (Adrenogenital disorders) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report other adrenogenital disorders on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What MS-DRG does E25.8 group to?

When other adrenogenital disorders is the principal diagnosis on an inpatient stay, it groups to MS-DRG 643, 644, 645, with relative weights from 0.7683 to 1.6461 depending on complications. Higher weights mean higher Medicare reimbursement.

What is the ICD-9 equivalent of E25.8?

Under the General Equivalence Mappings, other adrenogenital disorders converts to ICD-9-CM 255.2 (adrenogenital disorders). The mapping is approximate, so confirm the match fits the documentation.

Footnotes

[1] Chronic - a chronic condition code indicates a condition lasting 12 months or longer and its effect on the patient based on one or both of the following criteria:

  • The condition results in the need for ongoing intervention with medical products,treatment, services, and special equipment
  • The condition places limitations on self-care, independent living, and social interactions.