2026 ICD-10-CM Diagnosis Code T50Poisoning by, adverse effect of and underdosing of diuretics and other and unspecified drugs, medicaments and biological substances

ICD-10-CM Codes›S00–T88›T36-T50›T50

ICD-10-CM T50
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

T50 is a non-billable ICD-10-CM category code for poisoning by, adverse effect of and underdosing of diuretics and other and unspecified drugs, medicaments and biological substances, so it cannot be submitted on claims. Use a more specific code from this category instead, such as T50.0X1A, T50.0X1D, T50.0X1S, and T50.0X2A.

Code Identity

ICD-10-CM Code
T50
Billable Status
No — Non-Billable Category
Code Describes
Poisoning by, adverse effect of and underdosing of diuretics and other and unspecified drugs, medicaments and biological substances
Chapter
T36-T50
Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances

Code Classification

ChapterS00–T88Injury, poisoning and certain other consequences of external causes
SectionT36-T50Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances
CategoryT50Poisoning by, adverse effect of and underdosing of diuretics and other and unspecified drugs, medicaments and biological substances
This CodeT50Poisoning by, adverse effect of and underdosing of diuretics and other and unspecified drugs, medicaments and biological substances

Specific Coding for Diuretics and oth and unsp drug/meds/biol substOverview

Non-specific codes like T50 require more characters. Use one of these billable codes instead:

  • T50.0 for Poisoning by, adverse effect of and underdosing of mineralocorticoids and their antagonists

  • T50.0X for Poisoning by, adverse effect of and underdosing of mineralocorticoids and their antagonists

  • T50.1 for Poisoning by, adverse effect of and underdosing of loop [high-ceiling] diuretics

  • T50.1X for Poisoning by, adverse effect of and underdosing of loop [high-ceiling] diuretics

  • T50.2 for Poisoning by, adverse effect of and underdosing of carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics

  • T50.2X for Poisoning by, adverse effect of and underdosing of carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics

  • T50.3 for Poisoning by, adverse effect of and underdosing of electrolytic, caloric and water-balance agents

  • T50.3X for Poisoning by, adverse effect of and underdosing of electrolytic, caloric and water-balance agents

  • T50.4 for Poisoning by, adverse effect of and underdosing of drugs affecting uric acid metabolism

  • T50.4X for Poisoning by, adverse effect of and underdosing of drugs affecting uric acid metabolism

  • T50.5 for Poisoning by, adverse effect of and underdosing of appetite depressants

  • T50.5X for Poisoning by, adverse effect of and underdosing of appetite depressants

  • T50.6 for Poisoning by, adverse effect of and underdosing of antidotes and chelating agents

  • T50.6X for Poisoning by, adverse effect of and underdosing of antidotes and chelating agents

  • T50.7 for Poisoning by, adverse effect of and underdosing of analeptics and opioid receptor antagonists

  • T50.7X for Poisoning by, adverse effect of and underdosing of analeptics and opioid receptor antagonists

  • T50.8 for Poisoning by, adverse effect of and underdosing of diagnostic agents

  • T50.8X for Poisoning by, adverse effect of and underdosing of diagnostic agents

  • T50.9 for Poisoning by, adverse effect of and underdosing of other and unspecified drugs, medicaments and biological substances

  • T50.90 for Poisoning by, adverse effect of and underdosing of unspecified drugs, medicaments and biological substances

  • T50.91 for Poisoning by, adverse effect of and underdosing of multiple unspecified drugs, medicaments and biological substances

  • T50.99 for Poisoning by, adverse effect of and underdosing of other drugs, medicaments and biological substances

  • T50.A for Poisoning by, adverse effect of and underdosing of bacterial vaccines

  • T50.A1 for Poisoning by, adverse effect of and underdosing of pertussis vaccine, including combinations with a pertussis component

  • T50.A2 for Poisoning by, adverse effect of and underdosing of mixed bacterial vaccines without a pertussis component

  • T50.A9 for Poisoning by, adverse effect of and underdosing of other bacterial vaccines

  • T50.B for Poisoning by, adverse effect of and underdosing of viral vaccines

  • T50.B1 for Poisoning by, adverse effect of and underdosing of smallpox vaccines

  • T50.B9 for Poisoning by, adverse effect of and underdosing of other viral vaccines

  • T50.Z for Poisoning by, adverse effect of and underdosing of other vaccines and biological substances

  • T50.Z1 for Poisoning by, adverse effect of and underdosing of immunoglobulin

  • T50.Z9 for Poisoning by, adverse effect of and underdosing of other vaccines and biological substances

Coding GuidelinesGuidance

When coding a poisoning or reaction to the improper use of a medication (e.g., overdose, wrong substance given or taken in error, wrong route of administration), first assign the appropriate code from categories T36-T50. The poisoning codes have an associated intent as their 5th or 6th character (accidental, intentional self-harm, assault and undetermined). If the intent of the poisoning is unknown or unspecified, code the intent as accidental intent. The undetermined intent is only for use if the documentation in the record specifies that the intent cannot be determined. Use additional code(s) for all manifestations of poisonings.

The appropriate 7th character is to be added to each code from block Poisoning by, adverse effect of and underdosing of diuretics and other and unspecified drugs, medicaments and biological substances (T50). Use the following options for the applicable episode of care:

  • A - initial encounter
  • D - subsequent encounter
  • S - sequela

Source: ICD-10-CM Official Guidelines for Coding and Reporting, FY 2026, published by CMS and the National Center for Health Statistics.

Tabular List NotesGuidance

Coding notes and annotation back-references applicable to this code.

7th Character Note

  • The appropriate 7th character is to be added to each code from category T50

7th Character

  • A - initial encounter
  • D - subsequent encounter
  • S - sequela

Patient EducationClinical

Drug Reactions

Most of the time, medicines make our lives better. They reduce aches and pains, fight infections, and control problems such as high blood pressure or diabetes. But medicines can also cause unwanted reactions, such as drug interactions, side effects, and allergies.

The full article covers:

  • What is a drug interaction?
  • What are side effects?
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  • How can I stay safe when taking medicines?

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About T50Overview

Is T50 a billable code?

No. This is a category header that groups the codes for poisoning by, adverse effect of and underdosing of diuretics and other and unspecified drugs, medicaments and biological substances, and headers cannot be submitted on claims. Claims for poisoning by, adverse effect of and underdosing of diuretics and other and unspecified drugs, medicaments and biological substances need a more specific code from this category, such as T50.0X1A, T50.0X1D, and T50.0X1S.