T50 - Poisoning by, adverse effect of and underdosing of diuretics and other and unspecified drugs, medicaments and biological substances

Version 2023
ICD-10:T50
Short Description:Diuretics and oth and unsp drug/meds/biol subst
Long Description:Poisoning by, adverse effect of and underdosing of diuretics and other and unspecified drugs, medicaments and biological substances
Status: Not Valid for Submission
Version:ICD-10-CM 2023
Code Classification:
  • Injury, poisoning and certain other consequences of external causes (S00–T98)
    • Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances (T36-T50)
      • Diuretics and oth and unsp drug/meds/biol subst (T50)

T50 is a non-specific and non-billable ICD-10 code code, consider using a code with a higher level of specificity for a diagnosis of poisoning by, adverse effect of and underdosing of diuretics and other and unspecified drugs, medicaments and biological substances. The code is not specific and is NOT valid for the year 2023 for the submission of HIPAA-covered transactions. Category or Header define the heading of a category of codes that may be further subdivided by the use of 4th, 5th, 6th or 7th characters.

Unspecified diagnosis codes like T50 are acceptable when clinical information is unknown or not available about a particular condition. Although a more specific code is preferable, unspecified codes should be used when such codes most accurately reflect what is known about a patient's condition. Specific diagnosis codes should not be used if not supported by the patient's medical record.

Coding Guidelines

When coding a poisoning or reaction to the improper use of a medication (e.g., overdose, wrong substance given or taken in error, wrong route of administration), first assign the appropriate code from categories T36-T50. The poisoning codes have an associated intent as their 5th or 6th character (accidental, intentional self-harm, assault and undetermined. If the intent of the poisoning is unknown or unspecified, code the intent as accidental intent. The undetermined intent is only for use if the documentation in the record specifies that the intent cannot be determined. Use additional code(s) for all manifestations of poisonings.

The appropriate 7th character is to be added to each code from block Diuretics and oth and unsp drug/meds/biol subst (T50). Use the following options for the aplicable episode of care:

Specific Coding for Diuretics and oth and unsp drug/meds/biol subst

Non-specific codes like T50 require more digits to indicate the appropriate level of specificity. Consider using any of the following ICD-10 codes with a higher level of specificity when coding for diuretics and oth and unsp drug/meds/biol subst:

  • NON-BILLABLE CODE - T50.0 for Poisoning by, adverse effect of and underdosing of mineralocorticoids and their antagonists
  • NON-BILLABLE CODE - T50.0X for Poisoning by, adverse effect of and underdosing of mineralocorticoids and their antagonists
  • NON-BILLABLE CODE - T50.1 for Poisoning by, adverse effect of and underdosing of loop [high-ceiling] diuretics
  • NON-BILLABLE CODE - T50.1X for Poisoning by, adverse effect of and underdosing of loop [high-ceiling] diuretics
  • NON-BILLABLE CODE - T50.2 for Poisoning by, adverse effect of and underdosing of carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics
  • NON-BILLABLE CODE - T50.2X for Poisoning by, adverse effect of and underdosing of carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics
  • NON-BILLABLE CODE - T50.3 for Poisoning by, adverse effect of and underdosing of electrolytic, caloric and water-balance agents
  • NON-BILLABLE CODE - T50.3X for Poisoning by, adverse effect of and underdosing of electrolytic, caloric and water-balance agents
  • NON-BILLABLE CODE - T50.4 for Poisoning by, adverse effect of and underdosing of drugs affecting uric acid metabolism
  • NON-BILLABLE CODE - T50.4X for Poisoning by, adverse effect of and underdosing of drugs affecting uric acid metabolism
  • NON-BILLABLE CODE - T50.5 for Poisoning by, adverse effect of and underdosing of appetite depressants
  • NON-BILLABLE CODE - T50.5X for Poisoning by, adverse effect of and underdosing of appetite depressants
  • NON-BILLABLE CODE - T50.6 for Poisoning by, adverse effect of and underdosing of antidotes and chelating agents
  • NON-BILLABLE CODE - T50.6X for Poisoning by, adverse effect of and underdosing of antidotes and chelating agents
  • NON-BILLABLE CODE - T50.7 for Poisoning by, adverse effect of and underdosing of analeptics and opioid receptor antagonists
  • NON-BILLABLE CODE - T50.7X for Poisoning by, adverse effect of and underdosing of analeptics and opioid receptor antagonists
  • NON-BILLABLE CODE - T50.8 for Poisoning by, adverse effect of and underdosing of diagnostic agents
  • NON-BILLABLE CODE - T50.8X for Poisoning by, adverse effect of and underdosing of diagnostic agents
  • NON-BILLABLE CODE - T50.9 for Poisoning by, adverse effect of and underdosing of other and unspecified drugs, medicaments and biological substances
  • NON-BILLABLE CODE - T50.90 for Poisoning by, adverse effect of and underdosing of unspecified drugs, medicaments and biological substances
  • NON-BILLABLE CODE - T50.91 for Poisoning by, adverse effect of and underdosing of multiple unspecified drugs, medicaments and biological substances
  • NON-BILLABLE CODE - T50.99 for Poisoning by, adverse effect of and underdosing of other drugs, medicaments and biological substances
  • NON-BILLABLE CODE - T50.A for Poisoning by, adverse effect of and underdosing of bacterial vaccines
  • NON-BILLABLE CODE - T50.A1 for Poisoning by, adverse effect of and underdosing of pertussis vaccine, including combinations with a pertussis component
  • NON-BILLABLE CODE - T50.A2 for Poisoning by, adverse effect of and underdosing of mixed bacterial vaccines without a pertussis component
  • NON-BILLABLE CODE - T50.A9 for Poisoning by, adverse effect of and underdosing of other bacterial vaccines
  • NON-BILLABLE CODE - T50.B for Poisoning by, adverse effect of and underdosing of viral vaccines
  • NON-BILLABLE CODE - T50.B1 for Poisoning by, adverse effect of and underdosing of smallpox vaccines
  • NON-BILLABLE CODE - T50.B9 for Poisoning by, adverse effect of and underdosing of other viral vaccines
  • NON-BILLABLE CODE - T50.Z for Poisoning by, adverse effect of and underdosing of other vaccines and biological substances
  • NON-BILLABLE CODE - T50.Z1 for Poisoning by, adverse effect of and underdosing of immunoglobulin
  • NON-BILLABLE CODE - T50.Z9 for Poisoning by, adverse effect of and underdosing of other vaccines and biological substances

Tabular List of Diseases and Injuries

The Tabular List of Diseases and Injuries is a list of ICD-10 codes, organized "head to toe" into chapters and sections with coding notes and guidance for inclusions, exclusions, descriptions and more. The following references are applicable to this diagnosis code:


7th Character Note

7th Character Note
Certain ICD-10-CM categories have applicable 7th characters. The applicable 7th character is required for all codes within the category, or as the notes in the Tabular List instruct. The 7th character must always be the 7th character in the data field. If a code that requires a 7th character is not 6 characters, a placeholder X must be used to fill in the empty characters.

7th Character

7th Character
Indicates that a seventh character is to be assigned to codes in a subcategory.

Patient Education


Drug Reactions

Most of the time, medicines make our lives better. They reduce aches and pains, fight infections, and control problems such as high blood pressure or diabetes. But medicines can also cause unwanted reactions, such as drug interactions, side effects, and allergies.

What is a drug interaction?

A drug interaction is a change in the way a drug acts in the body when taken with certain other drugs, foods, or supplements or when taken while you have certain medical conditions. Examples include:

Interactions could cause a drug to be more or less effective, cause side effects, or change the way one or both drugs work.

What are side effects?

Side effects are unwanted, usually unpleasant, effects caused by medicines. Most are mild, such as a stomachache, dry mouth, or drowsiness, and go away after you stop taking the medicine. Others can be more serious. Sometimes a drug can interact with a disease that you have and cause a side effect. For example, if you have a heart condition, certain decongestants can cause you to have a rapid heartbeat.

What are drug allergies?

Drug allergies are another type of reaction. They can range from mild to life-threatening. Skin reactions, such as hives and rashes, are the most common type. Anaphylaxis, a serious allergic reaction, is less common.

How can I stay safe when taking medicines?

When you start a new prescription or over-the-counter medicine, make sure you understand how to take it correctly. Know which other medicines, foods, and supplements you need to avoid. Always talk to your health care provider or pharmacist if you have questions about your medicines.


[Learn More in MedlinePlus]

Code History