2027 ICD-10-CM Diagnosis Code E24Cushing's syndrome

ICD-10-CM Codes›E00–E89›E20-E35›E24

ICD-10-CM E24
CMSSource: CMS FY 2027 ICD-10-CM dataset · Effective Oct 1, 2026 – Sep 30, 2027

E24 is a non-billable ICD-10-CM category code for Cushing's syndrome, so it cannot be submitted on claims. Use a more specific code from this category instead, such as E24.0, E24.1, E24.2, and E24.3.

Code Identity

ICD-10-CM Code
E24
Billable Status
No — Non-Billable Category
Code Describes
Cushing's syndrome
Short Description
Cushing's syndrome
Same as the full description in the CMS dataset.
Chapter
E20-E35
Disorders of other endocrine glands

Code Classification

ChapterE00–E89Endocrine, nutritional and metabolic diseases
SectionE20-E35Disorders of other endocrine glands
CategoryE24Cushing's syndrome
This CodeE24Cushing's syndrome

Specific Coding for Cushing's syndromeOverview

Non-specific codes like E24 require more characters. Use one of these billable codes instead:

  • Use E24.0 for Pituitary-dependent Cushing's disease

  • Use E24.1 for Nelson's syndrome

  • Use E24.2 for Drug-induced Cushing's syndrome

  • Use E24.3 for Ectopic ACTH syndrome

  • Use E24.4 for Alcohol-induced pseudo-Cushing's syndrome

  • Use E24.8 for Other Cushing's syndrome

  • Use E24.9 for Cushing's syndrome, unspecified

Instructional NotesGuidance

Instructions from the official ICD-10-CM Tabular List that apply to E24: its own notes plus those printed at block E20-E35 and Chapter 4. A note printed at a category, block or chapter applies to every code under it.

Excludes1

Not coded here: the excluded code is never reported together with this one, unless the two conditions are unrelated.

On E24 itself
  • congenital adrenal hyperplasia (E25.0)
From Block E20-E35 Disorders of other endocrine glands applies to 99 codes
From Chapter 4 (E00-E89) Endocrine, nutritional and metabolic diseases applies to 973 codes
  • transitory endocrine and metabolic disorders specific to newborn (P70-P74)

Notes

General instructions on how these codes are used.

From Chapter 4 (E00-E89) Endocrine, nutritional and metabolic diseases applies to 973 codes
  • All neoplasms, whether functionally active or not, are classified in Chapter 2. Appropriate codes in this chapter (i.e. E05.8, E07.0, E16-E31, E34.-) may be used as additional codes to indicate either functional activity by neoplasms and ectopic endocrine tissue or hyperfunction and hypofunction of endocrine glands associated with neoplasms and other conditions classified elsewhere.

Source: CMS ICD-10-CM Tabular List. How to read instructional notes.

Referenced in Other NotesGuidance

Instructional notes printed at other codes that name E24, its category, or a range that includes it.

Excludes1 2

These codes carry an Excludes1 note naming E24: they are not reported together with it, unless the two conditions are unrelated.

  • E22 Hyperfunction of pituitary gland
    Cushing's syndrome (E24.-)
  • E27.0 Other adrenocortical overactivity
    Cushing's syndrome (E24.-)

Code First 2

These codes say to code first a condition named in the note, and E24 is one of the conditions named.

  • E08 Diabetes mellitus due to underlying condition
    Cushing's syndrome (E24.-)
  • G63 Polyneuropathy in diseases classified elsewhere
    endocrine disease, except diabetes (E00-E07, E15-E16, E20-E34) names E20-E34, which includes this code

Notes 1

These notes mention E24.

  • Chapter 4 (E00-E89) Endocrine, nutritional and metabolic diseases
    All neoplasms, whether functionally active or not, are classified in Chapter 2. Appropriate codes in this chapter (i.e. E05.8, E07.0, E16-E31, E34.-) may be used as additional codes to indicate either functional activity by neoplasms and ectopic endocrine tissue or hyperfunction and hypofunction of endocrine glands associated with neoplasms and other conditions classified elsewhere. names E16-E31, which includes this code

Clinical InformationClinical

  • Cushing Syndrome

    a condition caused by prolonged exposure to excess levels of cortisol (hydrocortisone) or other glucocorticoids from endogenous or exogenous sources. it is characterized by upper body obesity; osteoporosis; hypertension; diabetes mellitus; hirsutism; amenorrhea; and excess body fluid. endogenous cushing syndrome or spontaneous hypercortisolism is divided into two groups, those due to an excess of adrenocorticotropin and those that are acth-independent.

Patient EducationClinical

Cushing's Syndrome

Cushing's syndrome is a hormonal disorder. The cause is long-term exposure to too much cortisol, a hormone that your adrenal gland makes. Sometimes, taking synthetic hormone medicine to treat an inflammatory disease leads to Cushing's. Some kinds of tumors produce a hormone that can cause your body to make too much cortisol.

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2026No changes
FY 2027CurrentCurrent code set, no changesEffective October 1, 2026 through September 30, 2027.

Questions About E24Overview

What is the ICD-10 code for Cushing's syndrome?

E24 is the ICD-10-CM category for Cushing's syndrome, but it is a non-billable header: claims need a more specific code from this category, listed on this page.

Is E24 (Cushing's syndrome) a billable code?

No. This is a category header that groups the codes for Cushing's syndrome, and headers cannot be submitted on claims. Claims for Cushing's syndrome need a more specific code from this category, such as E24.0, E24.1, and E24.2.

Can E24 be reported with E25.0?

Not as a rule. The Excludes1 note on E24 lists "congenital adrenal hyperplasia (E25.0)". An Excludes1 note means the excluded code is never reported together with this one; the only exception is when the two conditions are unrelated to each other (Official Guidelines, Section I.A.12.a).