ICD-10-CM Code E24

Cushing's syndrome

Version 2021 Non-Billable Code

Not Valid for Submission

E24 is a "header" nonspecific and non-billable code code, consider using a code with a higher level of specificity for a diagnosis of cushing's syndrome. The code is NOT valid for the year 2021 for the submission of HIPAA-covered transactions.

ICD-10:E24
Short Description:Cushing's syndrome
Long Description:Cushing's syndrome

Consider the following ICD-10 codes with a higher level of specificity:

  • E24.0 - Pituitary-dependent Cushing's disease
  • E24.1 - Nelson's syndrome
  • E24.2 - Drug-induced Cushing's syndrome
  • E24.3 - Ectopic ACTH syndrome
  • E24.4 - Alcohol-induced pseudo-Cushing's syndrome
  • E24.8 - Other Cushing's syndrome
  • E24.9 - ... unspecified

Tabular List of Diseases and Injuries

The Tabular List of Diseases and Injuries is a list of ICD-10 codes, organized "head to toe" into chapters and sections with guidance for inclusions, exclusions, descriptions and more. The following references are applicable to the code E24:

Type 1 Excludes

Type 1 Excludes
A type 1 excludes note is a pure excludes note. It means "NOT CODED HERE!" An Excludes1 note indicates that the code excluded should never be used at the same time as the code above the Excludes1 note. An Excludes1 is used when two conditions cannot occur together, such as a congenital form versus an acquired form of the same condition.
  • congenital adrenal hyperplasia E25.0

Clinical Information

  • CUSHING SYNDROME-. a condition caused by prolonged exposure to excess levels of cortisol hydrocortisone or other glucocorticoids from endogenous or exogenous sources. it is characterized by upper body obesity; osteoporosis; hypertension; diabetes mellitus; hirsutism; amenorrhea; and excess body fluid. endogenous cushing syndrome or spontaneous hypercortisolism is divided into two groups those due to an excess of adrenocorticotropin and those that are acth independent.

Code Classification

  • Endocrine, nutritional and metabolic diseases (E00–E90)
    • Disorders of other endocrine glands (E20-E35)
      • Cushing's syndrome (E24)

Code History

  • FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016
    (First year ICD-10-CM implemented into the HIPAA code set)
  • FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
  • FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
  • FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
  • FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020
  • FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021

Information for Patients


Cushing's Syndrome

Also called: Hypercortisolism

Cushing's syndrome is a hormonal disorder. The cause is long-term exposure to too much cortisol, a hormone that your adrenal gland makes. Sometimes, taking synthetic hormone medicine to treat an inflammatory disease leads to Cushing's. Some kinds of tumors produce a hormone that can cause your body to make too much cortisol.

Cushing's syndrome is rare. Some symptoms are

  • Upper body obesity
  • Thin arms and legs
  • Severe fatigue and muscle weakness
  • High blood pressure
  • High blood sugar
  • Easy bruising

Lab tests can show if you have it and find the cause. Your treatment will depend on why you have too much cortisol. If it is because you have been taking synthetic hormones, a lower dose may control your symptoms. If the cause is a tumor, surgery and other therapies may be needed.

NIH: National Institute of Diabetes and Digestive and Kidney Diseases

  • ACTH blood test (Medical Encyclopedia)
  • Cortisol - urine (Medical Encyclopedia)
  • Cushing disease (Medical Encyclopedia)
  • Cushing syndrome (Medical Encyclopedia)
  • Cushing syndrome - exogenous (Medical Encyclopedia)
  • Cushing syndrome due to adrenal tumor (Medical Encyclopedia)
  • Dexamethasone suppression test (Medical Encyclopedia)
  • Ectopic Cushing syndrome (Medical Encyclopedia)

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