2026 ICD-10-CM Diagnosis Code D83.0Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function
ICD-10-CM Codes›D50–D89›D80-D89›D83
- Billable — Valid for Submission
- CC — Complication or Comorbidity
- Risk Adjusts — HCC 114
- Chronic Condition
D83.0 is a billable ICD-10-CM diagnosis code for common variable immunodeficiency with predominant abnormalities of B-cell numbers and function. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 814 through 816. As a secondary diagnosis, it counts as a complication or comorbidity (CC) and moves an inpatient stay to a higher severity level within its MS-DRG family. It does not count, however, when the principal diagnosis is one of 44 closely related codes. Coders also document this condition as common variable immunodeficiency with predominant abnormalities of B-cell numbers and functions. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Immunity disorders.
For Medicare Advantage risk adjustment, D83.0 maps to CMS-HCC Category 114 (Common Variable and Combined Immunodeficiencies) under the V28 model, adding a risk factor of about 2.262 for a community, non-dual, aged beneficiary in payment year 2026.
Code Identity
Code Classification
Medicare Risk Adjustment (HCC)Billing
D83.0 maps to a payment category in the CMS-HCC model used to risk-adjust Medicare Advantage payments. Weights are the published community factors for payment year 2026.
Source: CMS Payment Year 2026 risk adjustment mappings and model software. Weights are relative factors, not dollar amounts; a beneficiary's total RAF also includes demographics and interactions. Browse all CMS-HCC categories.
Approximate SynonymsGuidance
Alternate terms and clinical phrases that map to this code.
- Common variable immunodeficiency with predominant abnormalities of B-cell numbers and functions
- Congenital sideroblastic anemia, B-cell immunodeficiency, periodic fever, developmental delay syndrome
Index to Diseases and InjuriesGuidance
Alphabetical index entries that point to this code.
Clinical ClassificationClinical
AHRQ’s CCSR groups this code into broader clinical categories.
Clinical InformationClinical
Common Variable Immunodeficiency
heterogeneous group of immunodeficiency syndromes characterized by hypogammaglobulinemia of most isotypes, variable b-cell defects, and the presence of recurrent bacterial infections.
Patient EducationClinical
Immune System and Disorders
Your immune system is a complex network of cells, tissues, and organs. Together they help the body fight infections and other diseases.
The full article covers:
- What is the immune system?
- What are the parts of the immune system?
- How does the immune system work?
- What are the types of immunity?
- What can go wrong with the immune system?
Read the full article at MedlinePlus
Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.
Convert D83.0 to ICD-9-CMHistory
The closest ICD-9-CM equivalents under the General Equivalence Mappings.
Code HistoryHistory
Questions About D83.0Overview
Is D83.0 (Common variable immunodeficiency) a billable code?
Yes. This is a billable ICD-10-CM code, specific enough to report common variable immunodeficiency with predominant abnormalities of B-cell numbers and function on HIPAA-covered claims from October 1, 2025 through September 30, 2026.
What MS-DRG does D83.0 group to?
When common variable immunodeficiency with predominant abnormalities of B-cell numbers and function is the principal diagnosis on an inpatient stay, it groups to MS-DRG 814, 815, 816, with relative weights from 0.6320 to 2.1267 depending on complications. Higher weights mean higher Medicare reimbursement.
Is D83.0 a CC or MCC?
CMS lists D83.0 as a CC (complication or comorbidity) for FY 2026. Reported as a secondary diagnosis, it moves the inpatient stay to a higher-weighted DRG within its severity family. It does not count when the principal diagnosis is one of the 44 closely related codes in its exclusion list.
What is the ICD-9 equivalent of D83.0?
Under the General Equivalence Mappings, common variable immunodeficiency with predominant abnormalities of B-cell numbers and function converts to ICD-9-CM 279.06 (common variabl immunodef). The mapping is approximate, so confirm the match fits the documentation.
What HCC is D83.0?
D83.0 (common variable immunodeficiency with predominant abnormalities of B-cell numbers and function) maps to CMS-HCC Category 114 (Common Variable and Combined Immunodeficiencies), commonly written as HCC 114, in the CMS-HCC V28 model used for Medicare Advantage risk adjustment in payment year 2026. It mapped to HCC 47 under the retired V24 model. It also maps in the PACE (CMS-HCC V22), ESRD (V21), and ESRD (V24) models. In the Part D prescription drug model it maps to RxHCC 99.
Does D83.0 risk-adjust for Medicare Advantage payment?
Yes. When documented and reported on a Medicare Advantage encounter, D83.0 adds a risk adjustment factor of about 2.262 to the beneficiary's RAF score for a community, non-dual, aged enrollee (published V28 weights range from 0.691 to 2.789 depending on the payment segment). HCC 114 sits at the top of its hierarchy, so no other condition category supersedes it. See the full factor table on the HCC 114 category page.
