2021 ICD-10-CM Code D81.9
Combined immunodeficiency, unspecified
Valid for Submission
D81.9 is a billable diagnosis code used to specify a medical diagnosis of combined immunodeficiency, unspecified. The code D81.9 is valid during the fiscal year 2021 from October 01, 2020 through September 30, 2021 for the submission of HIPAA-covered transactions.
The ICD-10-CM code D81.9 might also be used to specify conditions or terms like achondrogenesis, achondroplasia, autosomal recessive scid, autosomal recessive severe combined immunodeficiency, benign combined immunodeficiency , combined immunodeficiency disease, etc.
Unspecified diagnosis codes like D81.9 are acceptable when clinical information is unknown or not available about a particular condition. Although a more specific code is preferable, unspecified codes should be used when such codes most accurately reflect what is known about a patient's condition. Specific diagnosis codes should not be used if not supported by the patient's medical record.
| ICD-10: | D81.9 |
| Short Description: | Combined immunodeficiency, unspecified |
| Long Description: | Combined immunodeficiency, unspecified |
Code Classification
Tabular List of Diseases and Injuries
The Tabular List of Diseases and Injuries is a list of ICD-10 codes, organized "head to toe" into chapters and sections with guidance for inclusions, exclusions, descriptions and more. The following references are applicable to the code D81.9:
Inclusion Terms
Inclusion TermsThese terms are the conditions for which that code is to be used. The terms may be synonyms of the code title, or, in the case of "other specified" codes, the terms are a list of the various conditions assigned to that code. The inclusion terms are not necessarily exhaustive. Additional terms found only in the Alphabetic Index may also be assigned to a code.
- Severe combined immunodeficiency disorder SCID NOS
Index to Diseases and Injuries
The Index to Diseases and Injuries is an alphabetical listing of medical terms, with each term mapped to one or more ICD-10 code(s). The following references for the code D81.9 are found in the index:
- - Agammaglobulinemia (acquired (secondary)) (nonfamilial) - D80.1
- - with
- - lymphopenia - D81.9
- - lymphopenic - D81.9
- - with
- - Immunodeficiency - D84.9
- - combined - D81.9
- - severe (SCID) - D81.9
- - severe combined (SCID) - D81.9
- - combined - D81.9
- - Syndrome - See Also: Disease;
- - combined immunity deficiency - D81.9
- - immunity deficiency, combined - D81.9
- - immunodeficiency
- - combined - D81.9
Approximate Synonyms
The following clinical terms are approximate synonyms or lay terms that might be used to identify the correct diagnosis code:
- Achondrogenesis
- Achondroplasia
- Autosomal recessive SCID
- Autosomal recessive severe combined immunodeficiency
- Benign combined immunodeficiency
- Combined immunodeficiency disease
- Combined immunodeficiency with faciooculoskeletal anomalies syndrome
- Combined immunodeficiency with granulomatosis
- Defects of the tubular bones and/or axial skeleton
- Hepatic veno-occlusive disease with immunodeficiency syndrome
- Obstruction of visceral vein
- Severe combined immunodeficiency disease
- Severe combined immunodeficiency with low T- and B-cell numbers
- Severe combined immunodeficiency with low T- and B-cell numbers
- Severe combined immunodeficiency with maternofetal engraftment
- Severe combined immunodeficiency, microcephaly, growth retardation, sensitivity to ionizing radiation syndrome
- Short-limb skeletal dysplasia with severe combined immunodeficiency
- Veno-occlusive disease of the liver
Clinical Information
- SEVERE COMBINED IMMUNODEFICIENCY-. group of rare congenital disorders characterized by impairment of both humoral and cell mediated immunity leukopenia and low or absent antibody levels. it is inherited as an x linked or autosomal recessive defect. mutations occurring in many different genes cause human severe combined immunodeficiency scid.
- X LINKED COMBINED IMMUNODEFICIENCY DISEASES-. forms of combined immunodeficiency caused by mutations in the gene for interleukin receptor common gamma subunit. both severe and non severe subtypes of the disease have been identified.
Diagnostic Related Groups - MS-DRG Mapping
The ICD-10 code D81.9 is grouped in the following groups for version MS-DRG V38.0 What are Diagnostic Related Groups?
The Diagnostic Related Groups (DRGs) are a patient classification scheme which provides a means of relating the type of patients a hospital treats. The DRGs divides all possible principal diagnoses into mutually exclusive principal diagnosis areas referred to as Major Diagnostic Categories (MDC). applicable from 10/01/2020 through 09/30/2021.
- 808 - MAJOR HEMATOLOGICAL AND IMMUNOLOGICAL DIAGNOSES EXCEPT SICKLE CELL CRISIS AND COAGULATION DISORDERS WITH MCC - Relative Weight: 2.1779
- 809 - MAJOR HEMATOLOGICAL AND IMMUNOLOGICAL DIAGNOSES EXCEPT SICKLE CELL CRISIS AND COAGULATION DISORDERS WITH CC - Relative Weight: 1.2217
- 810 - MAJOR HEMATOLOGICAL AND IMMUNOLOGICAL DIAGNOSES EXCEPT SICKLE CELL CRISIS AND COAGULATION DISORDERS WITHOUT CC/MCC - Relative Weight: 0.9607
Convert D81.9 to ICD-9 Code
The General Equivalency Mapping (GEM) crosswalk indicates an approximate mapping between the ICD-10 code D81.9 its ICD-9 equivalent. The approximate mapping means there is not an exact match between the ICD-10 code and the ICD-9 code and the mapped code is not a precise representation of the original code.
- 279.2 - Combined immunity defic (Approximate Flag)
Information for Patients
Immune System and Disorders
Your immune system is a complex network of cells, tissues, and organs that work together to defend against germs. It helps your body to recognize these "foreign" invaders. Then its job is to keep them out, or if it can't, to find and destroy them.
If your immune system cannot do its job, the results can be serious. Disorders of the immune system include
- Allergy and asthma - immune responses to substances that are usually not harmful
- Immune deficiency diseases - disorders in which the immune system is missing one or more of its parts
- Autoimmune diseases - diseases causing your immune system to attack your own body's cells and tissues by mistake
NIH: National Institute of Allergy and Infectious Diseases
- Agammaglobulinemia (Medical Encyclopedia)
- Aging changes in immunity (Medical Encyclopedia)
- Chronic granulomatous disease (Medical Encyclopedia)
- Graft-versus-host disease (Medical Encyclopedia)
- Histiocytosis (Medical Encyclopedia)
- Hyperimmunoglobulin E syndrome (Medical Encyclopedia)
- Immune response (Medical Encyclopedia)
- Immunodeficiency disorders (Medical Encyclopedia)
- Selective deficiency of IgA (Medical Encyclopedia)
[Learn More]
Code History
- FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021
- FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020
- FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
- FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
- FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
- FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016 (First year ICD-10-CM implemented into the HIPAA code set)