HCC 114: Common Variable and Combined Immunodeficiencies ICD-10-CM
CMS-HCC Category 114 (Common Variable and Combined Immunodeficiencies) is a payment HCC in the V28 Medicare Advantage risk adjustment model. For payment year 2026 it adds a risk adjustment factor between 0.691 and 2.789 to a beneficiary's RAF score depending on the payment segment (2.262 for a community, non-dual, aged enrollee). 18 ICD-10-CM diagnosis codes map to HCC 114. It sits at the top of its hierarchy: no other condition category supersedes it.
RAF Weight by Payment Segment 7 segments
| Payment Segment | Relative Factor |
|---|---|
| Community, non-dual, aged | 2.262 |
| Community, partial-benefit dual, aged | 2.137 |
| Community, full-benefit dual, aged | 2.016 |
| Community, non-dual, disabled | 2.598 |
| Community, partial-benefit dual, disabled | 2.789 |
| Community, full-benefit dual, disabled | 2.670 |
| Institutional | 0.691 |
A beneficiary is scored in exactly one segment, set by Medicaid (dual) status, aged or disabled entitlement, and residence. Factors are relative weights, not dollar amounts; new-enrollee segments score on demographics only. HCC 114 in turn supersedes HCC 115 (Specified Immunodeficiencies and White Blood Cell Disorders).
ICD-10-CM Codes That Map to HCC 114 18 codes
- D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis from V24 HCC 47
- D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers from V24 HCC 47
- D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers from V24 HCC 47
- D81.30 Adenosine deaminase deficiency, unspecified from V24 HCC 47
- D81.31 Severe combined immunodeficiency due to adenosine deaminase deficiency from V24 HCC 47
- D81.32 Adenosine deaminase 2 deficiency from V24 HCC 47
- D81.39 Other adenosine deaminase deficiency from V24 HCC 47
- D81.5 Purine nucleoside phosphorylase [PNP] deficiency from V24 HCC 47
- D81.6 Major histocompatibility complex class I deficiency from V24 HCC 47
- D81.7 Major histocompatibility complex class II deficiency from V24 HCC 47
- D81.82 Activated Phosphoinositide 3-kinase Delta Syndrome [APDS] from V24 HCC 47
- D81.89 Other combined immunodeficiencies from V24 HCC 47
- D81.9 Combined immunodeficiency, unspecified from V24 HCC 47
- D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function from V24 HCC 47
- D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders from V24 HCC 47
- D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells from V24 HCC 47
- D83.8 Other common variable immunodeficiencies from V24 HCC 47
- D83.9 Common variable immunodeficiency, unspecified from V24 HCC 47
Every code above carries the full HCC 114 weight when documented and reported on a Medicare Advantage encounter. The code link opens its full page with the complete risk adjustment card.
Questions About HCC 114
What is HCC 114 in the CMS-HCC model?
HCC 114 is CMS-HCC Category 114 (Common Variable and Combined Immunodeficiencies) in the V28 risk adjustment model. It covers 18 ICD-10-CM diagnosis codes that raise a Medicare Advantage beneficiary's risk score when documented.
What is the RAF weight for HCC 114?
For payment year 2026, HCC 114 adds 2.262 to the RAF score of a community, non-dual, aged beneficiary. The published weights range from 0.691 to 2.789 across the seven payment segments shown above.
Related References
Source: Centers for Medicare & Medicaid Services, Payment Year 2026 risk adjustment mapping and model software releases (CMS-HCC V28), applied to the FY 2026 ICD-10-CM code set. ICD List is not affiliated with CMS.
