HCC 114: Common Variable and Combined Immunodeficiencies ICD-10-CM
CMS-HCC Category 114 (Common Variable and Combined Immunodeficiencies) is a payment HCC in the V28 Medicare Advantage risk adjustment model. For payment year 2026 it adds a risk adjustment factor between 0.691 and 2.789 to a beneficiary's RAF score depending on the payment segment (2.262 for a community, non-dual, aged enrollee). 18 ICD-10-CM diagnosis codes map to HCC 114. It sits at the top of its hierarchy: no other condition category supersedes it.
RAF Weight by Payment Segment 7 segments
| Payment Segment | Relative Factor |
|---|---|
| Community, non-dual, aged | 2.262 |
| Community, partial-benefit dual, aged | 2.137 |
| Community, full-benefit dual, aged | 2.016 |
| Community, non-dual, disabled | 2.598 |
| Community, partial-benefit dual, disabled | 2.789 |
| Community, full-benefit dual, disabled | 2.670 |
| Institutional | 0.691 |
A beneficiary is scored in exactly one segment, set by Medicaid (dual) status, aged or disabled entitlement, and residence. Factors are relative weights, not dollar amounts; new-enrollee segments score on demographics only. HCC 114 in turn supersedes HCC 115 (Specified Immunodeficiencies and White Blood Cell Disorders).
ICD-10-CM Codes That Map to HCC 114 18 codes
- D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis from V24 HCC 47
- D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers from V24 HCC 47
- D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers from V24 HCC 47
- D81.30 Adenosine deaminase deficiency, unspecified from V24 HCC 47
- D81.31 Severe combined immunodeficiency due to adenosine deaminase deficiency from V24 HCC 47
- D81.32 Adenosine deaminase 2 deficiency from V24 HCC 47
- D81.39 Other adenosine deaminase deficiency from V24 HCC 47
- D81.5 Purine nucleoside phosphorylase [PNP] deficiency from V24 HCC 47
- D81.6 Major histocompatibility complex class I deficiency from V24 HCC 47
- D81.7 Major histocompatibility complex class II deficiency from V24 HCC 47
- D81.82 Activated Phosphoinositide 3-kinase Delta Syndrome [APDS] from V24 HCC 47
- D81.89 Other combined immunodeficiencies from V24 HCC 47
- D81.9 Combined immunodeficiency, unspecified from V24 HCC 47
- D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function from V24 HCC 47
- D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders from V24 HCC 47
- D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells from V24 HCC 47
- D83.8 Other common variable immunodeficiencies from V24 HCC 47
- D83.9 Common variable immunodeficiency, unspecified from V24 HCC 47
Every code above carries the full HCC 114 weight when documented and reported on a Medicare Advantage encounter. The code link opens its full page with the complete risk adjustment card.
Questions About HCC 114
What is HCC 114 in the CMS-HCC model?
HCC 114 is CMS-HCC Category 114 (Common Variable and Combined Immunodeficiencies) in the V28 risk adjustment model. It covers 18 ICD-10-CM diagnosis codes that raise a Medicare Advantage beneficiary's risk score when documented.
What is the RAF weight for HCC 114?
For payment year 2026, HCC 114 adds 2.262 to the RAF score of a community, non-dual, aged beneficiary (living at home, age 65 or over, not also enrolled in Medicaid). The published weights range from 0.691 to 2.789 across the seven payment segments shown above.
Related References
Source: Centers for Medicare & Medicaid Services, Payment Year 2026 risk adjustment mapping and model software releases (CMS-HCC V28), applied to the FY 2026 ICD-10-CM code set. ICD List is not affiliated with CMS.
