Hemolytic anemias (D55-D59)

ICD-10 codes D55-D59 classify various types of hemolytic anemias, which are conditions characterized by the destruction of red blood cells. This range includes anemia caused by enzyme deficiencies, inherited disorders like thalassemia, sickle-cell conditions, hereditary membrane defects, and acquired forms of hemolytic anemia.

The codes starting with D55 capture anemias due to enzyme disorders such as glucose-6-phosphate dehydrogenase (G6PD) deficiency, a well-known cause often referred to as favism or G-6-PD variant anemia. Thalassemia syndromes fall under D56, including alpha, beta, delta-beta, and other variants, often linked by synonyms like Hemoglobin H disease and Hemoglobin E-beta thalassemia. The D57 series details sickle-cell disorders, covering sickle-cell anemia with or without crisis and associated complications like acute chest syndrome and splenic sequestration. Codes beginning D58 address hereditary hemolytic anemias such as hereditary spherocytosis and elliptocytosis, conditions caused by defects in red blood cell membranes. Finally, D59 concerns acquired hemolytic anemias, including drug-induced autoimmune types, hemolytic-uremic syndrome, and paroxysmal nocturnal hemoglobinuria. These codes provide precise classifications for hemolytic anemias based on cause and clinical presentation, assisting accurate diagnosis and treatment coding.