2021 ICD-10-CM Code D84.1
Defects in the complement system
Valid for Submission
D84.1 is a billable diagnosis code used to specify a medical diagnosis of defects in the complement system. The code D84.1 is valid during the fiscal year 2021 from October 01, 2020 through September 30, 2021 for the submission of HIPAA-covered transactions.
The ICD-10-CM code D84.1 might also be used to specify conditions or terms like acquired angioedema due to c1 inhibitor autoantibody, acquired c1 esterase inhibitor deficiency, alternative pathway deficiency, anaphylotoxin inactivator deficiency, angioedema due to disorder of kinin metabolism , angioedema due to disorder of kinin metabolism, etc.
ICD-10: | D84.1 |
Short Description: | Defects in the complement system |
Long Description: | Defects in the complement system |
Code Classification
Tabular List of Diseases and Injuries
The Tabular List of Diseases and Injuries is a list of ICD-10 codes, organized "head to toe" into chapters and sections with guidance for inclusions, exclusions, descriptions and more. The following references are applicable to the code D84.1:
Inclusion Terms
Inclusion TermsThese terms are the conditions for which that code is to be used. The terms may be synonyms of the code title, or, in the case of "other specified" codes, the terms are a list of the various conditions assigned to that code. The inclusion terms are not necessarily exhaustive. Additional terms found only in the Alphabetic Index may also be assigned to a code.
- C1 esterase inhibitor C1-INH deficiency
Index to Diseases and Injuries
The Index to Diseases and Injuries is an alphabetical listing of medical terms, with each term mapped to one or more ICD-10 code(s). The following references for the code D84.1 are found in the index:
- - Angioedema (allergic) (any site) (with urticaria) - T78.3
- - hereditary - D84.1
- - Bannister's disease - T78.3
- - hereditary - D84.1
- - Defect, defective - Q89.9
- - complement system - D84.1
- - Deficiency, deficient
- - C1 esterase inhibitor (C1-INH) - D84.1
- - Edema, edematous (infectious) (pitting) (toxic) - R60.9
- - angioneurotic (allergic) (any site) (with urticaria) - T78.3
- - hereditary - D84.1
- - circumscribed, acute - T78.3
- - hereditary - D84.1
- - essential, acute - T78.3
- - hereditary - D84.1
- - glottis, glottic, glottidis (obstructive) (passive) - J38.4
- - allergic - T78.3
- - hereditary - D84.1
- - allergic - T78.3
- - periodic - T78.3
- - hereditary - D84.1
- - Quincke's - T78.3
- - hereditary - D84.1
- - angioneurotic (allergic) (any site) (with urticaria) - T78.3
- - Giant
- - urticaria - T78.3
- - hereditary - D84.1
- - urticaria - T78.3
- - Quincke's disease or edema - T78.3
- - hereditary - D84.1
- - Urticaria - L50.9
- - with angioneurotic edema - T78.3
- - hereditary - D84.1
- - giant - T78.3
- - hereditary - D84.1
- - larynx - T78.3
- - hereditary - D84.1
- - with angioneurotic edema - T78.3
Approximate Synonyms
The following clinical terms are approximate synonyms or lay terms that might be used to identify the correct diagnosis code:
- Acquired angioedema due to C1 inhibitor autoantibody
- Acquired C1 esterase inhibitor deficiency
- Alternative pathway deficiency
- Anaphylotoxin inactivator deficiency
- Angioedema due to disorder of kinin metabolism
- Angioedema due to disorder of kinin metabolism
- Angioedema due to disorder of kinin metabolism
- Autoimmune angioedema
- Autoimmune urticaria and/or angioedema
- Classical complement pathway abnormality
- Combined complement 6 and 7 deficiencies
- Complement 1q beta chain deficiency
- Complement 1q deficiency
- Complement 1q dysfunction
- Complement 1r deficiency
- Complement 1s deficiency
- Complement 2 deficiency
- Complement 4 binding protein deficiency
- Complement 4 deficiency
- Complement 4A deficiency
- Complement 4B deficiency
- Complement 5 deficiency
- Complement 5 dysfunction
- Complement 5a inhibitor deficiency
- Complement 6 deficiency
- Complement 7 deficiency
- Complement 8 alpha-gamma deficiency
- Complement 8 beta chain deficiency
- Complement 8 beta chain dysfunction
- Complement 9 deficiency
- Complement abnormality
- Complement component 3 deficiency
- Complement component deficiency
- Complement deficiency disease
- Complement receptor 1 deficiency
- Complement receptor 3 deficiency
- Complement receptor deficiency
- Complement regulatory factor defect
- Coombs negative hemolytic anemia
- Cutis laxa with complement deficiency
- Cutis laxa, acquired type
- Decay accelerating factor deficiency
- Disorder of complement
- Factor B deficiency
- Factor D deficiency
- Factor H deficiency
- Familial C3B inhibitor deficiency syndrome
- Hereditary angioedema
- Hereditary C1 esterase inhibitor deficiency - deficient factor
- Hereditary C1 esterase inhibitor deficiency - dysfunctional factor
- Homologous restriction factor deficiency
- Immunodeficiency due to MASP-2 deficiency
- Panniculitis due to immunological disorder
- Panniculitis with complement deficiency
- Primary CD59 deficiency
- Properdin deficiency disease
- Recurrent Neisseria infection due to factor D deficiency
- Terminal component deficiency
Convert D84.1 to ICD-9 Code
The General Equivalency Mapping (GEM) crosswalk indicates an approximate mapping between the ICD-10 code D84.1 its ICD-9 equivalent. The approximate mapping means there is not an exact match between the ICD-10 code and the ICD-9 code and the mapped code is not a precise representation of the original code.
Information for Patients
Immune System and Disorders
Your immune system is a complex network of cells, tissues, and organs that work together to defend against germs. It helps your body to recognize these "foreign" invaders. Then its job is to keep them out, or if it can't, to find and destroy them.
If your immune system cannot do its job, the results can be serious. Disorders of the immune system include
- Allergy and asthma - immune responses to substances that are usually not harmful
- Immune deficiency diseases - disorders in which the immune system is missing one or more of its parts
- Autoimmune diseases - diseases causing your immune system to attack your own body's cells and tissues by mistake
NIH: National Institute of Allergy and Infectious Diseases
- Agammaglobulinemia (Medical Encyclopedia)
- Aging changes in immunity (Medical Encyclopedia)
- Chronic granulomatous disease (Medical Encyclopedia)
- Graft-versus-host disease (Medical Encyclopedia)
- Histiocytosis (Medical Encyclopedia)
- Hyperimmunoglobulin E syndrome (Medical Encyclopedia)
- Immune response (Medical Encyclopedia)
- Immunodeficiency disorders (Medical Encyclopedia)
- Selective deficiency of IgA (Medical Encyclopedia)
[Learn More]
Complement component 8 deficiency Complement component 8 deficiency is a disorder that causes the immune system to malfunction, resulting in a form of immunodeficiency. Immunodeficiencies are conditions in which the immune system is not able to protect the body effectively from foreign invaders such as bacteria. People with complement component 8 deficiency have a significantly increased risk of recurrent bacterial infections, particularly by a bacterium called Neisseria meningitidis. Infection by this bacterium causes inflammation of the membranes surrounding the brain and spinal cord (meningitis). Although meningitis can be life-threatening, individuals with complement component 8 deficiency are less likely to die from the infection than people in the general population who contract it.The severity of complement component 8 deficiency varies widely. While some people with this condition experience one or more infections, others do not have any health problems related to the disorder.There are two types of complement component 8 deficiency, types I and II, classified by their genetic cause. The two types have the same signs and symptoms.
[Learn More]
Code History
- FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021
- FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020
- FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
- FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
- FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
- FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016 (First year ICD-10-CM implemented into the HIPAA code set)