2026 ICD-10-CM Diagnosis Code D82Immunodeficiency associated with other major defects

ICD-10-CM Codes›D50–D89›D80-D89›D82

ICD-10-CM D82
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

D82 is a non-billable ICD-10-CM category code for immunodeficiency associated with other major defects, so it cannot be submitted on claims. Use a more specific code from this category instead, such as D82.0, D82.1, D82.2, and D82.3.

Code Identity

ICD-10-CM Code
D82
Billable Status
No — Non-Billable Category
Code Describes
Immunodeficiency associated with other major defects
Chapter
D80-D89
Certain disorders involving the immune mechanism

Code Classification

ChapterD50–D89Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
SectionD80-D89Certain disorders involving the immune mechanism
CategoryD82Immunodeficiency associated with other major defects
This CodeD82Immunodeficiency associated with other major defects

Specific Coding for Immunodeficiency associated with other major defectsOverview

Non-specific codes like D82 require more characters. Use one of these billable codes instead:

  • Use D82.0 for Wiskott-Aldrich syndrome

  • Use D82.1 for Di George's syndrome

  • Use D82.2 for Immunodeficiency with short-limbed stature

  • Use D82.3 for Immunodeficiency following hereditary defective response to Epstein-Barr virus

  • Use D82.4 for Hyperimmunoglobulin E [IgE] syndrome

  • Use D82.8 for Immunodeficiency associated with other specified major defects

  • Use D82.9 for Immunodeficiency associated with major defect, unspecified

Tabular List NotesGuidance

Coding notes and annotation back-references applicable to this code.

Type 1 Excludes

  • ataxia telangiectasia Louis-Bar G11.3

Patient EducationClinical

Immune System and Disorders

Your immune system is a complex network of cells, tissues, and organs. Together they help the body fight infections and other diseases.

The full article covers:

  • What is the immune system?
  • What are the parts of the immune system?
  • How does the immune system work?
  • What are the types of immunity?
  • What can go wrong with the immune system?

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About D82Overview

Is D82 (Immunodeficiency associated with other major defects) a billable code?

No. This is a category header that groups the codes for immunodeficiency associated with other major defects, and headers cannot be submitted on claims. Claims for immunodeficiency associated with other major defects need a more specific code from this category, such as D82.0, D82.1, and D82.2.