Immunodeficiency

Alphabetical Index

Use the alphabetical index for the main term immunodeficiency to review the available sub terms and properly select the ICD-10 code with the highest degree of specificity. Instructional notations will guide the coder with information such as "see", "see also", "with", "without", "due to", and "code by site".

  • Immunodeficiency - D84.9 Immunodeficiency, unspecified
    • antibody with
      • hyperimmunoglobulinemia - D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinemia
      • near-normal immunoglobulins - D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinemia
    • autosomal recessive, Swiss type - D80.0 Hereditary hypogammaglobulinemia
    • combined - D81.9 Combined immunodeficiency, unspecified
      • biotin-dependent carboxylase - D81.819 Biotin-dependent carboxylase deficiency, unspecified
        • biotinidase - D81.810 Biotinidase deficiency
        • holocarboxylase synthetase - D81.818 Other biotin-dependent carboxylase deficiency
        • specified type NEC - D81.818 Other biotin-dependent carboxylase deficiency
      • severe (SCID) - D81.9 Combined immunodeficiency, unspecified
        • with
          • low or normal B-cell numbers - D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers
          • low T- and B-cell numbers - D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers
          • reticular dysgenesis - D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis
      • specified type NEC - D81.89 Other combined immunodeficiencies
    • common variable - D83.9 Common variable immunodeficiency, unspecified
      • specified type NEC - D83.8 Other common variable immunodeficiencies
      • with
        • abnormalities of B-cell numbers and function - D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function
        • autoantibodies to B- or T-cells - D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells
        • immunoregulatory T-cell disorders - D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders
    • following hereditary defective response to Epstein-Barr virus (EBV) - D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus
    • selective, immunoglobulin
      • A (IgA) - D80.2 Selective deficiency of immunoglobulin A [IgA]
      • G (IgG) (subclasses) - D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses
      • M (IgM) - D80.4 Selective deficiency of immunoglobulin M [IgM]
    • severe combined (SCID) - D81.9 Combined immunodeficiency, unspecified
      • due to adenosine deaminase deficiency - D81.31 Severe combined immunodeficiency due to adenosine deaminase deficiency
    • specified type NEC - D84.8 Other specified immunodeficiencies
    • with
      • adenosine-deaminase deficiency - See Also: Deficiency, adenosine deaminase; - D81.30 Adenosine deaminase deficiency, unspecified
      • antibody defects - D80.9 Immunodeficiency with predominantly antibody defects, unspecified
        • specified type NEC - D80.8 Other immunodeficiencies with predominantly antibody defects
      • hyperimmunoglobulinemia - D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinemia
      • increased immunoglobulin M (IgM) - D80.5 Immunodeficiency with increased immunoglobulin M [IgM]
      • major defect - D82.9 Immunodeficiency associated with major defect, unspecified
        • specified type NEC - D82.8 Immunodeficiency associated with other specified major defects
      • partial albinism - D82.8 Immunodeficiency associated with other specified major defects
      • short-limbed stature - D82.2 Immunodeficiency with short-limbed stature
      • thrombocytopenia and eczema - D82.0 Wiskott-Aldrich syndrome
    • X-linked, with increased IgM - D80.5 Immunodeficiency with increased immunoglobulin M [IgM]

Clinical Terms

The following are some of the clinical term definitions related or applicable to immunodeficiency within the ICD-10 index for Diseases and Injuries.

Biotinidase: An enzyme which catalyzes the release of BIOTIN from biocytin. In human, defects in the enzyme are the cause of the organic acidemia MULTIPLE CARBOXYLASE DEFICIENCY or BIOTINIDASE DEFICIENCY.