Immunodeficiency associated with other major defects (D82)

The ICD-10 code D82 encompasses immunodeficiencies linked to significant underlying defects, including specific syndromes like Wiskott-Aldrich syndrome (D82.0) and Di George's syndrome (D82.1). These codes are used to classify immune system disorders that occur alongside developmental or genetic abnormalities.

This section covers a range of immune deficiencies associated with major developmental issues. For example, D82.0 is assigned to Wiskott-Aldrich syndrome, also known by synonyms such as "dense body defect" or "immunodeficiency with major anomalies." Similarly, D82.1 codes for Di George's syndrome, which relates to thymic aplasia or dysplasia causing immune problems. Other codes like D82.3 represent immunodeficiency from a hereditary defective response to Epstein-Barr virus, sometimes called "X-linked lymphoproliferative disease." Hyperimmunoglobulin E syndrome is identified under D82.4, also known as "chemotactic disorder." These ICD-10 codes provide precise categorization essential for healthcare providers and coders handling conditions where immune deficiency is linked to complex, major physiological defects.