Immunodeficiency associated with other major defects (D82) ICD-10-CM
The D82 code range covers immunodeficiency associated with other major defects with 8 ICD-10-CM diagnosis codes. 7 of them are billable and valid for claim submission in fiscal year 2026, and the category headers group them but cannot themselves be billed.
Type 1 Excludes
A type 1 excludes note is a pure excludes note. It means "NOT CODED HERE!" An Excludes1 note indicates that the code excluded should never be used at the same time as the code above the Excludes1 note. An Excludes1 is used when two conditions cannot occur together, such as a congenital form versus an acquired form of the same condition.
- ataxia telangiectasia [Louis-Bar] G11.3
Codes in the D82 Range 8 codes · 7 billable
- D82 Immunodeficiency associated with other major defectsNon-billable
- D82.0 Wiskott-Aldrich syndrome
- D82.1 Di George's syndrome
- D82.2 Immunodeficiency with short-limbed stature
- D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus
- D82.4 Hyperimmunoglobulin E [IgE] syndrome
- D82.8 Immunodeficiency associated with other specified major defects
- D82.9 Immunodeficiency associated with major defect, unspecified
About the D82 Code Range
The ICD-10 code D82 encompasses immunodeficiencies linked to significant underlying defects, including specific syndromes like Wiskott-Aldrich syndrome (D82.0) and Di George's syndrome (D82.1). These codes are used to classify immune system disorders that occur alongside developmental or genetic abnormalities.
This section covers a range of immune deficiencies associated with major developmental issues. For example, D82.0 is assigned to Wiskott-Aldrich syndrome, also known by synonyms such as "dense body defect" or "immunodeficiency with major anomalies." Similarly, D82.1 codes for Di George's syndrome, which relates to thymic aplasia or dysplasia causing immune problems. Other codes like D82.3 represent immunodeficiency from a hereditary defective response to Epstein-Barr virus, sometimes called "X-linked lymphoproliferative disease." Hyperimmunoglobulin E syndrome is identified under D82.4, also known as "chemotactic disorder." These ICD-10 codes provide precise categorization essential for healthcare providers and coders handling conditions where immune deficiency is linked to complex, major physiological defects.
Questions About This Page
How many billable codes are in the D82 range?
Of the 8 codes in this range, 7 are billable and valid for claim submission from October 1, 2025 through September 30, 2026. Category header codes group them but cannot be reported on claims.
What does the D82 range classify?
The range classifies immunodeficiency associated with other major defects. Each code links to its own reference page with billing status, MS-DRG grouping, coding notes, and clinical information.
Related References
Source: CMS FY 2026 ICD-10-CM Tabular List and order file, effective October 1, 2025 through September 30, 2026.
