2027 ICD-10-CM Diagnosis Code D64.9Anemia, unspecified

ICD-10-CM Codes›D50–D89›D60-D64›D64

ICD-10-CM D64.9
CMSSource: CMS FY 2027 ICD-10-CM dataset · Effective Oct 1, 2026 – Sep 30, 2027

D64.9 is a billable ICD-10-CM diagnosis code for anemia, unspecified. It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027) and groups to MS-DRG 811 through 812. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Aplastic anemia.

Code Identity

ICD-10-CM Code
D64.9
Billable Status
Yes — Valid for Submission
Code Describes
Anemia, unspecified
Short Description
Anemia, unspecified
Same as the full description in the CMS dataset.
Parent Code
D64
Other anemias

Code Classification

ChapterD50–D89Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
SectionD60-D64Aplastic and other anemias and other bone marrow failure syndromes
CategoryD64Other anemias
This CodeD64.9Anemia, unspecified

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Anemia
  • Anemia caused by zidovudine
  • Anemia co-occurrent and due to chronic kidney disease stage 3
  • Anemia co-occurrent with human immunodeficiency virus infection
  • Anemia due to multiple mechanisms
  • Anemia due to unknown mechanism
  • Anemia in chronic kidney disease
  • Anemia in mother complicating childbirth
  • Anemia in mother complicating pregnancy, childbirth AND/OR puerperium
  • Anemia of renal disease
  • Benign intracranial hypertension
  • Benign intracranial hypertension due to anemia
  • Central nervous system calcification, deafness, tubular acidosis, anemia syndrome
  • Chronic anemia
  • Disorder of cellular component of blood caused by antiretroviral drug
  • Hemoglobin below reference range
  • Normocytic anemia
  • Normocytic normochromic anemia
  • Pericarditis associated with severe chronic anemia
  • Relative anemia

Instructional NotesGuidance

Instructions from the official ICD-10-CM Tabular List that apply to D64.9: its own notes plus those printed at D64 and Chapter 3. A note printed at a category, block or chapter applies to every code under it.

Excludes1

Not coded here: the excluded code is never reported together with this one, unless the two conditions are unrelated.

From D64 Other anemias applies to 8 codes
  • refractory anemia (D46.-)
  • refractory anemia with excess blasts in transformation [RAEB T] (C92.0-)

Excludes2

Not included here: the excluded condition is not part of this code, but a patient may have both, so both codes may be reported.

From Chapter 3 (D50-D89) Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism applies to 324 codes
  • autoimmune disease (systemic) NOS (M35.9)
  • certain conditions originating in the perinatal period (P00-P96)
  • complications of pregnancy, childbirth and the puerperium (O00-O9A)
  • congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)
  • endocrine, nutritional and metabolic diseases (E00-E88)
  • human immunodeficiency virus [HIV] disease (B20)
  • injury, poisoning and certain other consequences of external causes (S00-T88)
  • neoplasms (C00-D49)
  • symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)

Source: CMS ICD-10-CM Tabular List. How to read instructional notes.

Referenced in Other NotesGuidance

Instructional notes printed at other codes that name D64.9, its category, or a range that includes it.

Excludes1 1

These codes carry an Excludes1 note naming D64.9: they are not reported together with it, unless the two conditions are unrelated.

  • D53.9 Nutritional anemia, unspecified
    anemia NOS (D64.9)

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR BLD003
Aplastic anemia
Default principal diagnosis: inpatient Yes · outpatient Yes

Clinical InformationClinical

  • Anemia

    a reduction in the number of circulating erythrocytes or in the quantity of hemoglobin.

Patient EducationClinical

Anemia

If you have anemia, your blood does not carry enough oxygen to the rest of your body. The most common cause of anemia is not having enough iron. Your body needs iron to make hemoglobin. Hemoglobin is an iron-rich protein that gives the red color to blood. It carries oxygen from the lungs to the rest of the body.

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert D64.9 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
285.9 Anemia NOS
Exact Match The mapping is direct, with no qualifiers.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2026No changes
FY 2027CurrentCurrent code set, no changesEffective October 1, 2026 through September 30, 2027.

Questions About D64.9Overview

What is the ICD-10 code for anemia, unspecified?

The ICD-10-CM code for anemia, unspecified is D64.9 (sometimes written as D649). It is billable on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

Is D64.9 (Other anemias) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report anemia, unspecified on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

What MS-DRG does D64.9 group to?

When anemia, unspecified is the principal diagnosis on an inpatient stay, it groups to MS-DRG 812, 811, with relative weights from 0.9237 to 1.3991 depending on complications. Higher weights mean higher Medicare reimbursement.

Can D64.9 be reported with a code from D46?

Not as a rule. The Excludes1 note at D64, which applies to D64.9, lists "refractory anemia (D46.-)". An Excludes1 note means the excluded code is never reported together with this one; the only exception is when the two conditions are unrelated to each other (Official Guidelines, Section I.A.12.a).

What is the ICD-9 equivalent of D64.9?

Under the General Equivalence Mappings, anemia, unspecified converts to ICD-9-CM 285.9 (anemia NOS). The mapping is a direct match.