MS-DRG · FY 2026 v43.0
MS-DRG 812 – Red Blood Cell Disorders without MCC
A Medical DRG in MDC 16 (Diseases & Disorders of Blood, Blood Forming Organs, Immunologic Disorders). Inpatient cases group to DRG 812 when the ICD-10-CM principal diagnosis is one of the 134 codes listed below and no secondary diagnosis on the MCC list is present. Its FY 2026 relative weight is 0.9182 with a geometric mean length of stay of 2.7 days.
Medical DRG – assigned by principal diagnosis✓ Official CMS v43.0 dataset
0.9182
Relative Weight
2.7
Geometric Mean LOS (days)
3.6
Arithmetic Mean LOS (days)
134
Principal Diagnosis Codes
Severity family
DRG 811with MCCWeight 1.4043 · GMLOS 3.7 daysDRG 812without MCCWeight 0.9182 · GMLOS 2.7 days
How a case is assigned to DRG 812
The grouper first assigns the case to MDC 16 from the principal diagnosis and finds no qualifying operating-room procedure (this is a Medical DRG; ICD-10-PCS codes do not drive assignment here), then applies the severity split from secondary diagnoses: with MCC → 811; without MCC → 812.
ICD-10-CM
Principal Diagnosis Codes 134 codes · 16 categories
134 of 134 shown
D46 Myelodysplastic syndromes11 codes
- D46.0 Refractory anemia without ring sideroblasts, so stated
- D46.1 Refractory anemia with ring sideroblasts
- D46.20 Refractory anemia with excess of blasts, unspecified
- D46.21 Refractory anemia with excess of blasts 1
- D46.22 Refractory anemia with excess of blasts 2
- D46.4 Refractory anemia, unspecified
- D46.9 Myelodysplastic syndrome, unspecified
- D46.A Refractory cytopenia with multilineage dysplasia
- D46.B Refractory cytopenia with multilineage dysplasia and ring sideroblasts
- D46.C Myelodysplastic syndrome with isolated del(5q) chromosomal abnormality
- D46.Z Other myelodysplastic syndromes
D50 Iron deficiency anemia4 codes
D51 Vitamin B12 deficiency anemia6 codes
- D51.0 Vitamin B12 deficiency anemia due to intrinsic factor deficiency
- D51.1 Vitamin B12 deficiency anemia due to selective vitamin B12 malabsorption with proteinuria
- D51.2 Transcobalamin II deficiency
- D51.3 Other dietary vitamin B12 deficiency anemia
- D51.8 Other vitamin B12 deficiency anemias
- D51.9 Vitamin B12 deficiency anemia, unspecified
D52 Folate deficiency anemia4 codes
D53 Other nutritional anemias5 codes
D55 Anemia due to enzyme disorders7 codes
- D55.0 Anemia due to glucose-6-phosphate dehydrogenase [G6PD] deficiency
- D55.1 Anemia due to other disorders of glutathione metabolism
- D55.21 Anemia due to pyruvate kinase deficiency
- D55.29 Anemia due to other disorders of glycolytic enzymes
- D55.3 Anemia due to disorders of nucleotide metabolism
- D55.8 Other anemias due to enzyme disorders
- D55.9 Anemia due to enzyme disorder, unspecified
D56 Thalassemia8 codes
D57 Sickle-cell disorders43 codes
- D57.00 Hb-SS disease with crisis, unspecified
- D57.01 Hb-SS disease with acute chest syndrome
- D57.02 Hb-SS disease with splenic sequestration
- D57.03 Hb-SS disease with cerebral vascular involvement
- D57.04 Hb-SS disease with dactylitis
- D57.09 Hb-SS disease with crisis with other specified complication
- D57.1 Sickle-cell disease without crisis
- D57.20 Sickle-cell/Hb-C disease without crisis
- D57.211 Sickle-cell/Hb-C disease with acute chest syndrome
- D57.212 Sickle-cell/Hb-C disease with splenic sequestration
- D57.213 Sickle-cell/Hb-C disease with cerebral vascular involvement
- D57.214 Sickle-cell/Hb-C disease with dactylitis
- D57.218 Sickle-cell/Hb-C disease with crisis with other specified complication
- D57.219 Sickle-cell/Hb-C disease with crisis, unspecified
- D57.3 Sickle-cell trait
- D57.40 Sickle-cell thalassemia without crisis
- D57.411 Sickle-cell thalassemia, unspecified, with acute chest syndrome
- D57.412 Sickle-cell thalassemia, unspecified, with splenic sequestration
- D57.413 Sickle-cell thalassemia, unspecified, with cerebral vascular involvement
- D57.414 Sickle-cell thalassemia, unspecified, with dactylitis
- D57.418 Sickle-cell thalassemia, unspecified, with crisis with other specified complication
- D57.419 Sickle-cell thalassemia, unspecified, with crisis
- D57.42 Sickle-cell thalassemia beta zero without crisis
- D57.431 Sickle-cell thalassemia beta zero with acute chest syndrome
- D57.432 Sickle-cell thalassemia beta zero with splenic sequestration
- D57.433 Sickle-cell thalassemia beta zero with cerebral vascular involvement
- D57.434 Sickle-cell thalassemia beta zero with dactylitis
- D57.438 Sickle-cell thalassemia beta zero with crisis with other specified complication
- D57.439 Sickle-cell thalassemia beta zero with crisis, unspecified
- D57.44 Sickle-cell thalassemia beta plus without crisis
- D57.451 Sickle-cell thalassemia beta plus with acute chest syndrome
- D57.452 Sickle-cell thalassemia beta plus with splenic sequestration
- D57.453 Sickle-cell thalassemia beta plus with cerebral vascular involvement
- D57.454 Sickle-cell thalassemia beta plus with dactylitis
- D57.458 Sickle-cell thalassemia beta plus with crisis with other specified complication
- D57.459 Sickle-cell thalassemia beta plus with crisis, unspecified
- D57.80 Other sickle-cell disorders without crisis
- D57.811 Other sickle-cell disorders with acute chest syndrome
- D57.812 Other sickle-cell disorders with splenic sequestration
- D57.813 Other sickle-cell disorders with cerebral vascular involvement
- D57.814 Other sickle-cell disorders with dactylitis
- D57.818 Other sickle-cell disorders with crisis with other specified complication
- D57.819 Other sickle-cell disorders with crisis, unspecified
D58 Other hereditary hemolytic anemias5 codes
D59 Acquired hemolytic anemia4 codes
D62 Acute posthemorrhagic anemia1 code
- D62 Acute posthemorrhagic anemia
D63 Anemia in chronic diseases classified elsewhere3 codes
D64 Other anemias8 codes
- D64.0 Hereditary sideroblastic anemia
- D64.1 Secondary sideroblastic anemia due to disease
- D64.2 Secondary sideroblastic anemia due to drugs and toxins
- D64.3 Other sideroblastic anemias
- D64.4 Congenital dyserythropoietic anemia
- D64.81 Anemia due to antineoplastic chemotherapy
- D64.89 Other specified anemias
- D64.9 Anemia, unspecified
D74 Methemoglobinemia3 codes
R71 Abnormality of red blood cells2 codes
T80 Complications following infusion, transfusion and therapeutic injection20 codes
- T80.30XA ABO incompatibility reaction due to transfusion of blood or blood products, unspecified, initial encounter
- T80.310A ABO incompatibility with acute hemolytic transfusion reaction, initial encounter
- T80.311A ABO incompatibility with delayed hemolytic transfusion reaction, initial encounter
- T80.319A ABO incompatibility with hemolytic transfusion reaction, unspecified, initial encounter
- T80.39XA Other ABO incompatibility reaction due to transfusion of blood or blood products, initial encounter
- T80.40XA Rh incompatibility reaction due to transfusion of blood or blood products, unspecified, initial encounter
- T80.410A Rh incompatibility with acute hemolytic transfusion reaction, initial encounter
- T80.411A Rh incompatibility with delayed hemolytic transfusion reaction, initial encounter
- T80.419A Rh incompatibility with hemolytic transfusion reaction, unspecified, initial encounter
- T80.49XA Other Rh incompatibility reaction due to transfusion of blood or blood products, initial encounter
- T80.89XA Other complications following infusion, transfusion and therapeutic injection, initial encounter
- T80.910A Acute hemolytic transfusion reaction, unspecified incompatibility, initial encounter
- T80.911A Delayed hemolytic transfusion reaction, unspecified incompatibility, initial encounter
- T80.919A Hemolytic transfusion reaction, unspecified incompatibility, unspecified as acute or delayed, initial encounter
- T80.92XA Unspecified transfusion reaction, initial encounter
- T80.A0XA Non-ABO incompatibility reaction due to transfusion of blood or blood products, unspecified, initial encounter
- T80.A10A Non-ABO incompatibility with acute hemolytic transfusion reaction, initial encounter
- T80.A11A Non-ABO incompatibility with delayed hemolytic transfusion reaction, initial encounter
- T80.A19A Non-ABO incompatibility with hemolytic transfusion reaction, unspecified, initial encounter
- T80.A9XA Other non-ABO incompatibility reaction due to transfusion of blood or blood products, initial encounter
ICD-10-PCS
Procedure Codes
Procedure codes do not drive assignment for this DRG. DRG 812 is a Medical DRG, assigned from the principal diagnosis above.
Frequently Asked Questions
What is MS-DRG 812?
MS-DRG 812 (Red Blood Cell Disorders without MCC) is a medical DRG in MDC 16 (Diseases & Disorders of Blood, Blood Forming Organs, Immunologic Disorders). Its FY 2026 relative weight is 0.9182 with a geometric mean length of stay of 2.7 days.
What is the difference between DRG 811, 812?
All 2 share the same base category; the severity of secondary diagnoses separates them: 811 (with MCC), 812 (without MCC). A major complication or comorbidity (MCC) places the case in the highest-weighted DRG of the family; a CC in the middle; neither in the lowest.
How many diagnosis codes group to DRG 812?
134 ICD-10-CM principal diagnosis codes group to this DRG, spanning 16 three-character categories.
What is the relative weight of DRG 812?
The FY 2026 relative weight of this DRG is 0.9182, meaning reimbursement of roughly 0.92 times the average Medicare inpatient case. Multiply by a hospital's blended base rate for the approximate payment.
Source: CMS ICD-10 MS-DRG v43.0 Definitions Manual and the FY 2026 IPPS Final Rule (Table 5), effective October 1, 2025 through September 30, 2026. We publish the DRG assignments as CMS defines them and add the navigation, search, and code links.
